| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BMH1 | BMH2 | YER177W | YDR099W | 14-3-3 protein, major isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of exocytosis, vesicle transport, Ras/MAPK and rapamycin-sensitive signaling, aggresome formation, spindle position checkpoint; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress; antiapoptotic gene similar to human 14-3-3; BMH1 has a paralog, BMH2, that arose from whole genome duplication. | 14-3-3 protein, minor isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of many processes including exocytosis, vesicle transport, Ras/MAPK signaling, and rapamycin-sensitive signaling; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress; abundance relative to Bmh1p increases during sporulation. | 0.999 |
| BMH1 | DSF2 | YER177W | YBR007C | 14-3-3 protein, major isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of exocytosis, vesicle transport, Ras/MAPK and rapamycin-sensitive signaling, aggresome formation, spindle position checkpoint; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress; antiapoptotic gene similar to human 14-3-3; BMH1 has a paralog, BMH2, that arose from whole genome duplication. | Protein DSF2; Deletion suppressor of mpt5 mutation; relocalizes from bud neck to cytoplasm upon DNA replication stress. | 0.587 |
| BMH2 | BMH1 | YDR099W | YER177W | 14-3-3 protein, minor isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of many processes including exocytosis, vesicle transport, Ras/MAPK signaling, and rapamycin-sensitive signaling; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress; abundance relative to Bmh1p increases during sporulation. | 14-3-3 protein, major isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of exocytosis, vesicle transport, Ras/MAPK and rapamycin-sensitive signaling, aggresome formation, spindle position checkpoint; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress; antiapoptotic gene similar to human 14-3-3; BMH1 has a paralog, BMH2, that arose from whole genome duplication. | 0.999 |
| BMH2 | BOP3 | YDR099W | YNL042W | 14-3-3 protein, minor isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of many processes including exocytosis, vesicle transport, Ras/MAPK signaling, and rapamycin-sensitive signaling; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress; abundance relative to Bmh1p increases during sporulation. | Protein of unknown function; potential Cdc28p substrate; overproduction confers resistance to methylmercury. | 0.637 |
| BMH2 | DSF2 | YDR099W | YBR007C | 14-3-3 protein, minor isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of many processes including exocytosis, vesicle transport, Ras/MAPK signaling, and rapamycin-sensitive signaling; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress; abundance relative to Bmh1p increases during sporulation. | Protein DSF2; Deletion suppressor of mpt5 mutation; relocalizes from bud neck to cytoplasm upon DNA replication stress. | 0.507 |
| BOP3 | BMH2 | YNL042W | YDR099W | Protein of unknown function; potential Cdc28p substrate; overproduction confers resistance to methylmercury. | 14-3-3 protein, minor isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of many processes including exocytosis, vesicle transport, Ras/MAPK signaling, and rapamycin-sensitive signaling; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress; abundance relative to Bmh1p increases during sporulation. | 0.637 |
| BOP3 | DSF2 | YNL042W | YBR007C | Protein of unknown function; potential Cdc28p substrate; overproduction confers resistance to methylmercury. | Protein DSF2; Deletion suppressor of mpt5 mutation; relocalizes from bud neck to cytoplasm upon DNA replication stress. | 0.660 |
| BOP3 | FIR1 | YNL042W | YER032W | Protein of unknown function; potential Cdc28p substrate; overproduction confers resistance to methylmercury. | Factor interacting with REF2; Protein involved in 3' mRNA processing; interacts with Ref2p; APCC(Cdh1) substrate; potential Cdc28p substrate. | 0.581 |
| BOP3 | IRC8 | YNL042W | YJL051W | Protein of unknown function; potential Cdc28p substrate; overproduction confers resistance to methylmercury. | Uncharacterized protein IRC8; Bud tip localized protein of unknown function; mRNA is targeted to the bud by a She2p dependent transport system; mRNA is cell cycle regulated via Fkh2p, peaking in G2/M phase; null mutant displays increased levels of spontaneous Rad52p foc. | 0.414 |
| DSF2 | BMH1 | YBR007C | YER177W | Protein DSF2; Deletion suppressor of mpt5 mutation; relocalizes from bud neck to cytoplasm upon DNA replication stress. | 14-3-3 protein, major isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of exocytosis, vesicle transport, Ras/MAPK and rapamycin-sensitive signaling, aggresome formation, spindle position checkpoint; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress; antiapoptotic gene similar to human 14-3-3; BMH1 has a paralog, BMH2, that arose from whole genome duplication. | 0.587 |
| DSF2 | BMH2 | YBR007C | YDR099W | Protein DSF2; Deletion suppressor of mpt5 mutation; relocalizes from bud neck to cytoplasm upon DNA replication stress. | 14-3-3 protein, minor isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of many processes including exocytosis, vesicle transport, Ras/MAPK signaling, and rapamycin-sensitive signaling; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress; abundance relative to Bmh1p increases during sporulation. | 0.507 |
| DSF2 | BOP3 | YBR007C | YNL042W | Protein DSF2; Deletion suppressor of mpt5 mutation; relocalizes from bud neck to cytoplasm upon DNA replication stress. | Protein of unknown function; potential Cdc28p substrate; overproduction confers resistance to methylmercury. | 0.660 |
| DSF2 | FIR1 | YBR007C | YER032W | Protein DSF2; Deletion suppressor of mpt5 mutation; relocalizes from bud neck to cytoplasm upon DNA replication stress. | Factor interacting with REF2; Protein involved in 3' mRNA processing; interacts with Ref2p; APCC(Cdh1) substrate; potential Cdc28p substrate. | 0.487 |
| DSF2 | IRC8 | YBR007C | YJL051W | Protein DSF2; Deletion suppressor of mpt5 mutation; relocalizes from bud neck to cytoplasm upon DNA replication stress. | Uncharacterized protein IRC8; Bud tip localized protein of unknown function; mRNA is targeted to the bud by a She2p dependent transport system; mRNA is cell cycle regulated via Fkh2p, peaking in G2/M phase; null mutant displays increased levels of spontaneous Rad52p foc. | 0.540 |
| DSF2 | MPT5 | YBR007C | YGL178W | Protein DSF2; Deletion suppressor of mpt5 mutation; relocalizes from bud neck to cytoplasm upon DNA replication stress. | Suppressor protein MPT5; mRNA-binding protein of the PUF family; binds to specific mRNAs, often in the 3' UTR; has broad specificity and binds to more than 1000 mRNAs (16% of the transcriptome); recruits the CCR4-NOT deadenylase complex to mRNAs along with Dhh1p and Dcp1p to promote deadenylation, decapping, and decay; also interacts with the Caf20p translational initiation repressor, affecting its mRNA target specificity. | 0.533 |
| DSF2 | MSS1 | YBR007C | YMR023C | Protein DSF2; Deletion suppressor of mpt5 mutation; relocalizes from bud neck to cytoplasm upon DNA replication stress. | tRNA modification GTPase MSS1, mitochondrial; Mitochondrial protein; forms a heterodimer complex with Mto1p that performs the 5-carboxymethylaminomethyl modification of the wobble uridine base in mitochondrial tRNAs; similar to human GTPBP3; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.830 |
| DSF2 | NPT1 | YBR007C | YOR209C | Protein DSF2; Deletion suppressor of mpt5 mutation; relocalizes from bud neck to cytoplasm upon DNA replication stress. | Nicotinate phosphoribosyltransferase; acts in the salvage pathway of NAD+ biosynthesis; required for silencing at rDNA and telomeres and has a role in silencing at mating-type loci; localized to the nucleus. | 0.585 |
| DSF2 | SLM3 | YBR007C | YDL033C | Protein DSF2; Deletion suppressor of mpt5 mutation; relocalizes from bud neck to cytoplasm upon DNA replication stress. | tRNA-specific 2-thiouridylase; responsible for 2-thiolation of the wobble base of mitochondrial tRNAs; human homolog TRMU is implicated in myoclonus epilepsy associated with ragged red fibers (MERRF), and can complement yeast null mutant. | 0.533 |
| DSF2 | SSN2 | YBR007C | YDR443C | Protein DSF2; Deletion suppressor of mpt5 mutation; relocalizes from bud neck to cytoplasm upon DNA replication stress. | Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; required for stable association of Srb10p-Srb11p kinase; essential for transcriptional regulation. | 0.485 |
| FIR1 | BOP3 | YER032W | YNL042W | Factor interacting with REF2; Protein involved in 3' mRNA processing; interacts with Ref2p; APCC(Cdh1) substrate; potential Cdc28p substrate. | Protein of unknown function; potential Cdc28p substrate; overproduction confers resistance to methylmercury. | 0.581 |
