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TIP1 protein (Saccharomyces cerevisiae) - STRING interaction network
"TIP1" - Major cell wall mannoprotein with possible lipase activity in Saccharomyces cerevisiae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
TIP1Major cell wall mannoprotein with possible lipase activity; transcription is induced by heat- and cold-shock; member of the Srp1p/Tip1p family of serine-alanine-rich proteins; Seems to have esterase activity. Prefers ester of fatty acids from 4 to 16 carbon atoms (210 aa)    
Predicted Functional Partners:
DSL1
Peripheral membrane protein needed for Golgi-to-ER retrograde traffic; forms a complex with Sec39p and Tip20p that interacts with ER SNAREs Sec20p and Use1p; component of the ER target site that interacts with coatomer; interacts with Cin5p; Required for protein transport between the Golgi and the endoplasmic reticulum. May tether coatomer-coated retrograde transport vesicles to the ER membrane through interaction with coatomer as well as the SNARE complex. May contribute to the stabilization of the SNARE complex (754 aa)
       
      0.859
UFE1
t-SNARE required for retrograde vesicular traffic and homotypic ER membrane fusion; forms a complex with the SNAREs Sec22p, Sec20p and Use1p to mediate fusion of Golgi-derived vesicles at the ER; Syntaxin required for targeting and fusion of Golgi- derived retrograde transport vesicles with the ER (346 aa)
       
      0.778
USE1
Essential SNARE protein localized to the ER, involved in retrograde traffic from the Golgi to the ER; forms a complex with the SNAREs Sec22p, Sec20p and Ufe1p; SNARE required for targeting and fusion of Golgi-derived retrograde transport vesicles with the ER (245 aa)
       
      0.749
SEC39
Component of the Dsl1p tethering complex that interacts with ER SNAREs Sec20p and Use1p; proposed to be involved in protein secretion; localizes to the ER and nuclear envelope; Required for protein transport between the Golgi and the endoplasmic reticulum. May contribute to tethering of coatomer- coated retrograde transport vesicles to the ER membrane through interaction with and stabilization of the SNARE complex (709 aa)
       
      0.742
SEC22
R-SNARE protein; assembles into SNARE complex with Bet1p, Bos1p and Sed5p; cycles between the ER and Golgi complex; involved in anterograde and retrograde transport between the ER and Golgi; synaptobrevin homolog; Nonessential SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER (214 aa)
       
      0.742
TIP20
Peripheral membrane protein required for fusion of COPI vesicles with the ER; prohibits back-fusion of COPII vesicles with the ER; forms a tethering complex with Sec39p and Dsl1p that interacts with ER SNAREs Sec20p and Use1p; Required for protein transport between the Golgi and the endoplasmic reticulum. May contribute to tethering of coatomer- coated retrograde transport vesicles to the ER membrane through interaction with and stabilization of the SNARE complex (701 aa)
       
      0.695
SEC20
Membrane glycoprotein v-SNARE involved in retrograde transport from the Golgi to the ER; required for N- and O-glycosylation in the Golgi but not in the ER; interacts with the Dsl1p complex through Tip20p; SNARE required for targeting and fusion of Golgi-derived retrograde transport vesicles with the ER (383 aa)
       
      0.621
ECM19
Protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; May be involved in cell wall organization and biogenesis (112 aa)
           
  0.579
LDB16
Protein of unknown function; null mutants have decreased net negative cell surface charge; GFP-fusion protein expression is induced in response to the DNA-damaging agent MMS; native protein is detected in purified mitochondria; May be involved in protein-linked oligosaccharide phosphorylation since the deletion reduces the negative charge of the cell surface (256 aa)
           
  0.487
ECM27
Protein of unknown function; may play a role in cell wall biosynthesis, mutants are hypersensitive to anti fungal, Papulacandin B; null mutants have increased plasmid loss; interacts with Pdr5p (725 aa)
           
  0.480
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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