node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFI1 | PFF1 | YOR129C | YBR074W | ARF3-interacting protein 1; Arf3p polarization-specific docking factor; required for the polarized distribution of the ADP-ribosylation factor, Arf3p; participates in polarity development and maintenance of a normal haploid budding pattern; interacts with Cnm7p. | Multi-spanning vacuolar membrane protease; glycosylated transmembrane protein bearing homology to the M28 family of metalloproteases; has a lumenal-facing protease domain; proposed role in vacuole physiology. | 0.550 |
APE3 | CPS1 | YBR286W | YJL172W | Vacuolar aminopeptidase Y; processed to mature form by Prb1p. | Vacuolar carboxypeptidase S; expression is induced under low-nitrogen conditions. | 0.785 |
APE3 | DAP2 | YBR286W | YHR028C | Vacuolar aminopeptidase Y; processed to mature form by Prb1p. | Dipeptidyl aminopeptidase; synthesized as a glycosylated precursor; localizes to the vacuolar membrane; similar to Ste13p. | 0.797 |
APE3 | PFF1 | YBR286W | YBR074W | Vacuolar aminopeptidase Y; processed to mature form by Prb1p. | Multi-spanning vacuolar membrane protease; glycosylated transmembrane protein bearing homology to the M28 family of metalloproteases; has a lumenal-facing protease domain; proposed role in vacuole physiology. | 0.831 |
APE3 | YDR132C | YBR286W | YDR132C | Vacuolar aminopeptidase Y; processed to mature form by Prb1p. | Uncharacterized protein YDR132C; Protein of unknown function; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress; YDR132C has a paralog, YLR108C, that arose from the whole genome duplication. | 0.406 |
APE3 | YGL242C | YBR286W | YGL242C | Vacuolar aminopeptidase Y; processed to mature form by Prb1p. | Ankyrin repeat-containing protein YGL242C; Protein of unknown function; N-terminally propionylated in vivo; deletion mutant is viable. | 0.423 |
CPS1 | APE3 | YJL172W | YBR286W | Vacuolar carboxypeptidase S; expression is induced under low-nitrogen conditions. | Vacuolar aminopeptidase Y; processed to mature form by Prb1p. | 0.785 |
CPS1 | DAP2 | YJL172W | YHR028C | Vacuolar carboxypeptidase S; expression is induced under low-nitrogen conditions. | Dipeptidyl aminopeptidase; synthesized as a glycosylated precursor; localizes to the vacuolar membrane; similar to Ste13p. | 0.790 |
CPS1 | PFF1 | YJL172W | YBR074W | Vacuolar carboxypeptidase S; expression is induced under low-nitrogen conditions. | Multi-spanning vacuolar membrane protease; glycosylated transmembrane protein bearing homology to the M28 family of metalloproteases; has a lumenal-facing protease domain; proposed role in vacuole physiology. | 0.490 |
DAP2 | APE3 | YHR028C | YBR286W | Dipeptidyl aminopeptidase; synthesized as a glycosylated precursor; localizes to the vacuolar membrane; similar to Ste13p. | Vacuolar aminopeptidase Y; processed to mature form by Prb1p. | 0.797 |
DAP2 | CPS1 | YHR028C | YJL172W | Dipeptidyl aminopeptidase; synthesized as a glycosylated precursor; localizes to the vacuolar membrane; similar to Ste13p. | Vacuolar carboxypeptidase S; expression is induced under low-nitrogen conditions. | 0.790 |
DAP2 | PFF1 | YHR028C | YBR074W | Dipeptidyl aminopeptidase; synthesized as a glycosylated precursor; localizes to the vacuolar membrane; similar to Ste13p. | Multi-spanning vacuolar membrane protease; glycosylated transmembrane protein bearing homology to the M28 family of metalloproteases; has a lumenal-facing protease domain; proposed role in vacuole physiology. | 0.592 |
PFF1 | AFI1 | YBR074W | YOR129C | Multi-spanning vacuolar membrane protease; glycosylated transmembrane protein bearing homology to the M28 family of metalloproteases; has a lumenal-facing protease domain; proposed role in vacuole physiology. | ARF3-interacting protein 1; Arf3p polarization-specific docking factor; required for the polarized distribution of the ADP-ribosylation factor, Arf3p; participates in polarity development and maintenance of a normal haploid budding pattern; interacts with Cnm7p. | 0.550 |
PFF1 | APE3 | YBR074W | YBR286W | Multi-spanning vacuolar membrane protease; glycosylated transmembrane protein bearing homology to the M28 family of metalloproteases; has a lumenal-facing protease domain; proposed role in vacuole physiology. | Vacuolar aminopeptidase Y; processed to mature form by Prb1p. | 0.831 |
PFF1 | CPS1 | YBR074W | YJL172W | Multi-spanning vacuolar membrane protease; glycosylated transmembrane protein bearing homology to the M28 family of metalloproteases; has a lumenal-facing protease domain; proposed role in vacuole physiology. | Vacuolar carboxypeptidase S; expression is induced under low-nitrogen conditions. | 0.490 |
PFF1 | DAP2 | YBR074W | YHR028C | Multi-spanning vacuolar membrane protease; glycosylated transmembrane protein bearing homology to the M28 family of metalloproteases; has a lumenal-facing protease domain; proposed role in vacuole physiology. | Dipeptidyl aminopeptidase; synthesized as a glycosylated precursor; localizes to the vacuolar membrane; similar to Ste13p. | 0.592 |
PFF1 | PTK1 | YBR074W | YKL198C | Multi-spanning vacuolar membrane protease; glycosylated transmembrane protein bearing homology to the M28 family of metalloproteases; has a lumenal-facing protease domain; proposed role in vacuole physiology. | Serine/threonine-protein kinase PTK1/STK1; Putative serine/threonine protein kinase; regulates spermine uptake; involved in polyamine transport; possible mitochondrial protein; PTK1 has a paralog, PTK2, that arose from the whole genome duplication. | 0.566 |
PFF1 | SKG1 | YBR074W | YKR100C | Multi-spanning vacuolar membrane protease; glycosylated transmembrane protein bearing homology to the M28 family of metalloproteases; has a lumenal-facing protease domain; proposed role in vacuole physiology. | Suppressor of lethality of KEX2 GAS1 double null mutant protein 1; Transmembrane protein with a role in cell wall polymer composition; localizes on inner surface of plasma membrane at bud and in daughter cell; SKG1 has a paralog, AIM20, that arose from the whole genome duplication; Belongs to the SKG1 family. | 0.604 |
PFF1 | YDR132C | YBR074W | YDR132C | Multi-spanning vacuolar membrane protease; glycosylated transmembrane protein bearing homology to the M28 family of metalloproteases; has a lumenal-facing protease domain; proposed role in vacuole physiology. | Uncharacterized protein YDR132C; Protein of unknown function; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress; YDR132C has a paralog, YLR108C, that arose from the whole genome duplication. | 0.491 |
PFF1 | YGL242C | YBR074W | YGL242C | Multi-spanning vacuolar membrane protease; glycosylated transmembrane protein bearing homology to the M28 family of metalloproteases; has a lumenal-facing protease domain; proposed role in vacuole physiology. | Ankyrin repeat-containing protein YGL242C; Protein of unknown function; N-terminally propionylated in vivo; deletion mutant is viable. | 0.501 |