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ECM8 protein (Saccharomyces cerevisiae) - STRING interaction network
"ECM8" - Non-essential protein of unknown function in Saccharomyces cerevisiae
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECM8Non-essential protein of unknown function; May be involved in cell wall organization and biogenesis (354 aa)    
Predicted Functional Partners:
ECM27
Protein of unknown function; may play a role in cell wall biosynthesis, mutants are hypersensitive to anti fungal, Papulacandin B; null mutants have increased plasmid loss; interacts with Pdr5p (725 aa)
           
  0.540
ECM11
Non-essential protein apparently involved in meiosis, GFP fusion protein is present in discrete clusters in the nucleus throughout mitosis; may be involved in maintaining chromatin structure; May be involved in cell wall organization and biogenesis (302 aa)
     
   
  0.499
ECM19
Protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; May be involved in cell wall organization and biogenesis (112 aa)
           
  0.446
TIP1
Major cell wall mannoprotein with possible lipase activity; transcription is induced by heat- and cold-shock; member of the Srp1p/Tip1p family of serine-alanine-rich proteins; Seems to have esterase activity. Prefers ester of fatty acids from 4 to 16 carbon atoms (210 aa)
           
  0.418
YOL024W
Putative protein of unknown function; predicted to have thiol-disulfide oxidoreductase active site (172 aa)
           
  0.418
COA4
Twin Cx(9)C protein involved in cytochrome c oxidase assembly or stability; localizes to the mitochondrial intermembrane space via the Mia40p-Erv1p system; interacts genetically with CYC1 and with cytochrome c oxidase assembly factors; Involved in cytochrome c oxidase assembly or stability (150 aa)
           
  0.418
BER1
Protein involved in microtubule-related processes; GFP-fusion protein localizes to the cytoplasm and is induced in response to the DNA-damaging agent MMS; YLR412W is not an essential gene; similar to Arabidopsis SRR1 gene; Involved in microtubule stability and kinetochore function. May be involved in protein N-terminus acetylation and/or proteasome biogenesis (274 aa)
           
  0.416
YOR289W
Putative protein of unknown function; transcription induced by the unfolded protein response; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus (251 aa)
           
  0.414
YLR030W
Putative protein of unknown function (263 aa)
           
  0.410
YIL024C
Putative protein of unknown function; non-essential gene; expression directly regulated by the metabolic and meiotic transcriptional regulator Ume6p (189 aa)
           
  0.410
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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