node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DIA3 | FAD1 | YDL024C | YDL045C | Probable acid phosphatase DIA3; Protein of unknown function; involved in invasive and pseudohyphal growth. | FAD synthase; Flavin adenine dinucleotide (FAD) synthetase; performs the second step in synthesis of FAD from riboflavin; mutation is functionally complemented by human FLAD1. | 0.900 |
DIA3 | PHO11 | YDL024C | YAR071W | Probable acid phosphatase DIA3; Protein of unknown function; involved in invasive and pseudohyphal growth. | One of three repressible acid phosphatases; glycoprotein that is transported to the cell surface by the secretory pathway; induced by phosphate starvation and coordinately regulated by PHO4 and PHO2; PHO11 has a paralog, PHO12, that arose from a segmental duplication. | 0.902 |
DIA3 | PHO12 | YDL024C | YHR215W | Probable acid phosphatase DIA3; Protein of unknown function; involved in invasive and pseudohyphal growth. | One of three repressible acid phosphatases; glycoprotein that is transported to the cell surface by the secretory pathway; pregulated by phosphate starvation; PHO12 has a paralog, PHO11, that arose from a segmental duplication. | 0.902 |
DIA3 | PHO3 | YDL024C | YBR092C | Probable acid phosphatase DIA3; Protein of unknown function; involved in invasive and pseudohyphal growth. | Constitutively expressed acid phosphatase similar to Pho5p; brought to the cell surface by transport vesicles; hydrolyzes thiamin phosphates in the periplasmic space, increasing cellular thiamin uptake; expression is repressed by thiamin. | 0.903 |
DIA3 | PHO5 | YDL024C | YBR093C | Probable acid phosphatase DIA3; Protein of unknown function; involved in invasive and pseudohyphal growth. | Repressible acid phosphatase; 1 of 3 repressible acid phosphatases that also mediates extracellular nucleotide-derived phosphate hydrolysis; secretory pathway derived cell surface glycoprotein; induced by phosphate starvation and coordinately regulated by PHO4 and PHO2; Belongs to the histidine acid phosphatase family. | 0.901 |
DIA3 | PHO8 | YDL024C | YDR481C | Probable acid phosphatase DIA3; Protein of unknown function; involved in invasive and pseudohyphal growth. | Repressible vacuolar alkaline phosphatase; regulated by levels of Pi and by Pho4p, Pho9p, Pho80p, Pho81p and Pho85p; dephosphorylates phosphotyrosyl peptides; contributes to NAD+ metabolism by producing nicotinamide riboside from NMN. | 0.900 |
DIA3 | RIB5 | YDL024C | YBR256C | Probable acid phosphatase DIA3; Protein of unknown function; involved in invasive and pseudohyphal growth. | Riboflavin synthase; catalyzes the last step of the riboflavin biosynthesis pathway. | 0.900 |
DIA3 | THI6 | YDL024C | YPL214C | Probable acid phosphatase DIA3; Protein of unknown function; involved in invasive and pseudohyphal growth. | Thiamine biosynthetic bifunctional enzyme; Thiamine-phosphate diphosphorylase and hydroxyethylthiazole kinase; required for thiamine biosynthesis; GFP-fusion protein localizes to the cytoplasm in a punctate pattern. | 0.908 |
DIA3 | THI80 | YDL024C | YOR143C | Probable acid phosphatase DIA3; Protein of unknown function; involved in invasive and pseudohyphal growth. | Thiamine pyrophosphokinase; phosphorylates thiamine to produce the coenzyme thiamine pyrophosphate (thiamine diphosphate). | 0.907 |
FAD1 | DIA3 | YDL045C | YDL024C | FAD synthase; Flavin adenine dinucleotide (FAD) synthetase; performs the second step in synthesis of FAD from riboflavin; mutation is functionally complemented by human FLAD1. | Probable acid phosphatase DIA3; Protein of unknown function; involved in invasive and pseudohyphal growth. | 0.900 |
FAD1 | PHO11 | YDL045C | YAR071W | FAD synthase; Flavin adenine dinucleotide (FAD) synthetase; performs the second step in synthesis of FAD from riboflavin; mutation is functionally complemented by human FLAD1. | One of three repressible acid phosphatases; glycoprotein that is transported to the cell surface by the secretory pathway; induced by phosphate starvation and coordinately regulated by PHO4 and PHO2; PHO11 has a paralog, PHO12, that arose from a segmental duplication. | 0.900 |
FAD1 | PHO12 | YDL045C | YHR215W | FAD synthase; Flavin adenine dinucleotide (FAD) synthetase; performs the second step in synthesis of FAD from riboflavin; mutation is functionally complemented by human FLAD1. | One of three repressible acid phosphatases; glycoprotein that is transported to the cell surface by the secretory pathway; pregulated by phosphate starvation; PHO12 has a paralog, PHO11, that arose from a segmental duplication. | 0.900 |
FAD1 | PHO3 | YDL045C | YBR092C | FAD synthase; Flavin adenine dinucleotide (FAD) synthetase; performs the second step in synthesis of FAD from riboflavin; mutation is functionally complemented by human FLAD1. | Constitutively expressed acid phosphatase similar to Pho5p; brought to the cell surface by transport vesicles; hydrolyzes thiamin phosphates in the periplasmic space, increasing cellular thiamin uptake; expression is repressed by thiamin. | 0.900 |
FAD1 | PHO5 | YDL045C | YBR093C | FAD synthase; Flavin adenine dinucleotide (FAD) synthetase; performs the second step in synthesis of FAD from riboflavin; mutation is functionally complemented by human FLAD1. | Repressible acid phosphatase; 1 of 3 repressible acid phosphatases that also mediates extracellular nucleotide-derived phosphate hydrolysis; secretory pathway derived cell surface glycoprotein; induced by phosphate starvation and coordinately regulated by PHO4 and PHO2; Belongs to the histidine acid phosphatase family. | 0.900 |
FAD1 | RIB5 | YDL045C | YBR256C | FAD synthase; Flavin adenine dinucleotide (FAD) synthetase; performs the second step in synthesis of FAD from riboflavin; mutation is functionally complemented by human FLAD1. | Riboflavin synthase; catalyzes the last step of the riboflavin biosynthesis pathway. | 0.812 |
PHO11 | DIA3 | YAR071W | YDL024C | One of three repressible acid phosphatases; glycoprotein that is transported to the cell surface by the secretory pathway; induced by phosphate starvation and coordinately regulated by PHO4 and PHO2; PHO11 has a paralog, PHO12, that arose from a segmental duplication. | Probable acid phosphatase DIA3; Protein of unknown function; involved in invasive and pseudohyphal growth. | 0.902 |
PHO11 | FAD1 | YAR071W | YDL045C | One of three repressible acid phosphatases; glycoprotein that is transported to the cell surface by the secretory pathway; induced by phosphate starvation and coordinately regulated by PHO4 and PHO2; PHO11 has a paralog, PHO12, that arose from a segmental duplication. | FAD synthase; Flavin adenine dinucleotide (FAD) synthetase; performs the second step in synthesis of FAD from riboflavin; mutation is functionally complemented by human FLAD1. | 0.900 |
PHO11 | PHO12 | YAR071W | YHR215W | One of three repressible acid phosphatases; glycoprotein that is transported to the cell surface by the secretory pathway; induced by phosphate starvation and coordinately regulated by PHO4 and PHO2; PHO11 has a paralog, PHO12, that arose from a segmental duplication. | One of three repressible acid phosphatases; glycoprotein that is transported to the cell surface by the secretory pathway; pregulated by phosphate starvation; PHO12 has a paralog, PHO11, that arose from a segmental duplication. | 0.978 |
PHO11 | PHO3 | YAR071W | YBR092C | One of three repressible acid phosphatases; glycoprotein that is transported to the cell surface by the secretory pathway; induced by phosphate starvation and coordinately regulated by PHO4 and PHO2; PHO11 has a paralog, PHO12, that arose from a segmental duplication. | Constitutively expressed acid phosphatase similar to Pho5p; brought to the cell surface by transport vesicles; hydrolyzes thiamin phosphates in the periplasmic space, increasing cellular thiamin uptake; expression is repressed by thiamin. | 0.922 |
PHO11 | PHO5 | YAR071W | YBR093C | One of three repressible acid phosphatases; glycoprotein that is transported to the cell surface by the secretory pathway; induced by phosphate starvation and coordinately regulated by PHO4 and PHO2; PHO11 has a paralog, PHO12, that arose from a segmental duplication. | Repressible acid phosphatase; 1 of 3 repressible acid phosphatases that also mediates extracellular nucleotide-derived phosphate hydrolysis; secretory pathway derived cell surface glycoprotein; induced by phosphate starvation and coordinately regulated by PHO4 and PHO2; Belongs to the histidine acid phosphatase family. | 0.984 |