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TYR1 protein (Saccharomyces cerevisiae) - STRING interaction network
"TYR1" - Prephenate dehydrogenase involved in tyrosine biosynthesis, expression is dependent on phenylalanine levels in Saccharomyces cerevisiae
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Predicted Interactions
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textmining
co-expression
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TYR1Prephenate dehydrogenase involved in tyrosine biosynthesis, expression is dependent on phenylalanine levels (452 aa)    
Predicted Functional Partners:
ARO7
Chorismate mutase, catalyzes the conversion of chorismate to prephenate to initiate the tyrosine/phenylalanine-specific branch of aromatic amino acid biosynthesis (256 aa)
   
  0.989
PHA2
Prephenate dehydratase, catalyzes the conversion of prephanate to phenylpyruvate, which is a step in the phenylalanine biosynthesis pathway (334 aa)
   
 
  0.982
HIS5
Histidinol-phosphate aminotransferase, catalyzes the seventh step in histidine biosynthesis; responsive to general control of amino acid biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts (385 aa)
   
 
  0.980
ARO8
Aromatic aminotransferase I, expression is regulated by general control of amino acid biosynthesis; General aromatic amino acid transaminase involved in several otherwise unrelated metabolic pathways. Responsible for phenylalanine and tyrosine biosynthesis. Active with glutamate, phenylalanine, tyrosine and tryptophan as amino donors and with phenylpyruvate, hydroxyphenylpyruvate, 2-oxoglutarate and pyruvate as amino acceptors. Also active with methionine, alpha- aminoadipate and leucine as amino donors when phenylpyruvate is the amino acceptor and in the reverse reactions with the cor [...] (500 aa)
       
  0.971
AAT1
Mitochondrial aspartate aminotransferase, catalyzes the conversion of oxaloacetate to aspartate in aspartate and asparagine biosynthesis; Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol (By similarity) (451 aa)
       
  0.970
AAT2
Cytosolic aspartate aminotransferase involved in nitrogen metabolism; localizes to peroxisomes in oleate-grown cells; Plays a key role in amino acid metabolism (418 aa)
       
  0.963
ARO9
Aromatic aminotransferase II, catalyzes the first step of tryptophan, phenylalanine, and tyrosine catabolism; General aromatic amino acid transaminase involved in several otherwise unrelated metabolic pathways. Mainly involved in tryptophan degradation. Active with phenylalanine, tyrosine and tryptophan as amino donors and with phenylpyruvate, hydroxyphenylpyruvate and pyruvate as amino acceptors. Does not accept glutamate or 2-oxoglutarate as substrates. Also active with methionine, leucine, glutamine and kynurenine. Catalyzes the formation of methionine from 2-keto-4-methylthiobutyra [...] (513 aa)
       
  0.961
ARO1
Pentafunctional arom protein, catalyzes steps 2 through 6 in the biosynthesis of chorismate, which is a precursor to aromatic amino acids; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis (1588 aa)
   
 
  0.908
THR4
Threonine synthase, conserved protein that catalyzes formation of threonine from O-phosphohomoserine; expression is regulated by the GCN4-mediated general amino acid control pathway; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (514 aa)
           
  0.903
ARO2
Bifunctional chorismate synthase and flavin reductase, catalyzes the conversion of 5-enolpyruvylshikimate 3-phosphate (EPSP) to form chorismate, which is a precursor to aromatic amino acids (376 aa)
     
  0.865
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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