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MTC4 protein (Saccharomyces cerevisiae) - STRING interaction network
"MTC4" - Protein of unknown function, required for normal growth rate at 15 degrees C in Saccharomyces cerevisiae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
MTC4Protein of unknown function, required for normal growth rate at 15 degrees C; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; mtc4 is synthetically sick with cdc13-1 (694 aa)    
Predicted Functional Partners:
ERG5
C-22 sterol desaturase, a cytochrome P450 enzyme that catalyzes the formation of the C-22(23) double bond in the sterol side chain in ergosterol biosynthesis; may be a target of azole antifungal drugs; Required to form the C-22(23) double bond in the sterol side chain (538 aa)
       
      0.687
YAL065C
Putative protein of unknown function; has homology to FLO1; possible pseudogene (128 aa)
           
  0.641
YBR259W
Putative protein of unknown function; YBR259W is not an essential gene (688 aa)
           
  0.637
SLM6
Protein with a potential role in actin cytoskeleton organization; gene exhibits synthetic genetic interaction with MSS4 encoding phosphatidylinositol 4-phosphate kinase (150 aa)
           
  0.627
LEM3
Membrane protein of the plasma membrane and ER, interacts specifically in vivo with the phospholipid translocase (flippase) Dnf1p; involved in translocation of phospholipids and alkylphosphocholine drugs across the plasma membrane; Involved in the asymmetrical organization of phosphatidylethanolamine in the plasma membrane (414 aa)
       
      0.507
VRP1
Proline-rich actin-associated protein involved in cytoskeletal organization and cytokinesis; related to mammalian Wiskott-Aldrich syndrome protein (WASP)-interacting protein (WIP); Involved in cytoskeletal organization and cellular growth. May exert its effects on the cytoskeleton directly, or indirectly via proline-binding proteins (e.g. profilin) or proteins possessing SH3 domains (817 aa)
       
      0.507
MTC6
Protein of unknown function; mtc6 is synthetically sick with cdc13-1; May be involved in telomere capping (526 aa)
       
      0.507
GEP5
Protein of unknown function, required for mitochondrial genome maintenance; detected in highly purified mitochondria in high-throughput studies; null mutant has decreased levels of cardiolipin and phosphatidylethanolamine; Essential for respiratory growth and required for maintenance of mtDNA. Required for cell survival in the absence of prohibitins (293 aa)
           
  0.487
SRL4
Protein of unknown function; involved in regulation of dNTP production; null mutant suppresses the lethality of lcd1 and rad53 mutations; expression is induced by Kar4p; May be involved in the regulation of dNTP production. Induces the SOS system when expressed in E.coli, therefore, it may play a role in DNA metabolism and/or in genome stability (281 aa)
           
  0.485
YER158C
Protein of unknown function, has similarity to Afr1p; potentially phosphorylated by Cdc28p (573 aa)
           
  0.457
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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