STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YCL042WPutative protein of unknown function; epitope-tagged protein localizes to the cytoplasm. (119 aa)    
Predicted Functional Partners:
YCR024C-B
Uncharacterized protein YCR024C-B; Putative protein of unknown function; identified by expression profiling and mass spectrometry.
   
  
 0.950
YCL001W-A
Putative protein of unknown function; YCL001W-A gene has similarity to DOM34 and is present in a region duplicated between chromosomes XIV and III; Belongs to the eukaryotic release factor 1 family. Pelota subfamily. Highly divergent.
      
 0.877
OCA4
Cytoplasmic protein required for replication of Brome mosaic virus; S. cerevisiae is a model system for studying replication of positive-strand RNA viruses in their natural hosts.
      
 0.835
YCL068C
Putative protein of unknown function.
   
  
 0.710
VBA3
Permease of basic amino acids in the vacuolar membrane; VBA3 has a paralog, VBA5, that arose from a segmental duplication; Belongs to the major facilitator superfamily.
      
 0.697
GLK1
Glucokinase-1; Glucokinase; catalyzes the phosphorylation of glucose at C6 in the first irreversible step of glucose metabolism; one of three glucose phosphorylating enzymes; expression regulated by non-fermentable carbon sources; GLK1 has a paralog, EMI2, that arose from the whole genome duplication; Belongs to the hexokinase family.
   
  
 0.672
FIG2
Factor-induced gene 2 protein; Cell wall adhesin, expressed specifically during mating; may be involved in maintenance of cell wall integrity during mating; FIG2 has a paralog, AGA1, that arose from the whole genome duplication.
      
 0.602
YCL001W-B
Putative protein of unknown function; present in a region duplicated between chromosomes XIV and III; YCL001W-B has a paralog, DOM34, that arose from the whole genome duplication; Belongs to the eukaryotic release factor 1 family. Pelota subfamily. Highly divergent.
      
 0.584
YCL049C
Uncharacterized protein YCL049C; Protein of unknown function; localizes to membrane fraction; YCL049C is not an essential gene.
   
  
 0.523
CTO1
Protein required for cold tolerance; involved in phosphate uptake; YCR015C is not an essential gene.
      
 0.518
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: ATCC 18824, Candida robusta, Mycoderma cerevisiae, NRRL Y-12632, S. cerevisiae, Saccharomyces capensis, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, yeast
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