STRINGSTRING
YCL049C protein (Saccharomyces cerevisiae) - STRING interaction network
"YCL049C" - Protein of unknown function in Saccharomyces cerevisiae
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
YCL049CProtein of unknown function; localizes to membrane fraction; YCL049C is not an essential gene (312 aa)    
Predicted Functional Partners:
YDR524C-B
Putative protein of unknown function (66 aa)
           
  0.697
TMN2
Protein with a role in cellular adhesion and filamentous growth; similar to Emp70p and Tmn3p; member of the evolutionarily conserved Transmembrane Nine family of proteins with nine membrane-spanning segments; With EMP70 and TMN3, plays a critical role in the late stages of a nutrient-controlled pathway notably regulating FLO11 gene expression. Acts downstream of RAS2 and TOR. Essential for cell adhesion and filamentous growth. May play a role as effector of cellular copper homeostasis (672 aa)
           
  0.579
MHF2
Putative protein of unknown function; mutant in a srs2 mutant background displays MMS hypersensitivity; ortholog of human MHF2, a component of the Fanconi anemia (FA) complex that is involved in maintaining genome stability; DNA-binding component of a FANCM-MHF complex involved in DNA damage repair and genome maintenance (PubMed-20347428). FANCM- MHF promotes gene conversion at blocked replication forks (By similarity) (80 aa)
           
  0.520
YCL048W-A
Putative protein of unknown function (79 aa)
           
  0.519
IRC10
Protein of unknown function; null mutant displays increased levels of spontaneous Rad52p foci (586 aa)
           
  0.514
YDR089W
Protein of unknown function; deletion confers resistance to Nickel (869 aa)
           
  0.513
TFB5
Component of the RNA polymerase II general transcription and DNA repair factor TFIIH; involved in transcription initiation and in nucleotide-excision repair; homolog of Chlamydomonas reinhardtii REX1-S protein involved in DNA repair; Acts as component of the general transcription and DNA repair factor IIH (TFIIH) core, which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA. TFIIH has CTD kinase and DNA-dependent ATPase activity, and is essential for polymerase II transcription in vitro. TFB5 is required for stab [...] (72 aa)
           
  0.483
LDB17
Protein involved in the regulation of endocytosis; transiently recruited to actin cortical patches in a SLA1-dependent manner after late coat component assembly; GFP-fusion protein localizes to the periphery, cytoplasm, bud, and bud neck; May be involved in protein-linked oligosaccharide phosphorylation since the deletion reduces the negative charge of the cell surface (491 aa)
           
  0.470
SNA4
Protein of unknown function, localized to the vacuolar outer membrane; predicted to be palmitoylated (140 aa)
           
  0.469
SPS22
Protein of unknown function, redundant with Sps2p for the organization of the beta-glucan layer of the spore wall; Redundant with SPS2 for the organization of the beta- glucan layer of the spore wall (463 aa)
           
  0.469
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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