Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
YCL076WPutative uncharacterized protein YCL076W; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. (247 aa)    
Predicted Functional Partners:
YNL337W
Putative UPF0320 protein YNL337W; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data.
   
  
 0.951
YCL065W
Putative uncharacterized protein YCL065W; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps HMLALPHA1.
   
  
 0.949
YFL063W
Putative UPF0320 protein YFL063W; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data.
   
  
 0.932
YCL068C
Putative protein of unknown function.
   
  
 0.921
YAR075W
Putative inosine-5'-monophosphate dehydrogenase-like protein YAR075W; Non-functional protein with homology IMP dehydrogenase; YAR073W/IMD1 and YAR075W comprise a continuous reading frame in most strains of S. cerevisiae; YAR073W/YAR075W together have a paralog, IMD2, that arose from a segmental duplication; Belongs to the IMPDH/GMPR family.
   
  
 0.919
CHA1
Catabolic L-serine/threonine dehydratase; Catabolic L-serine (L-threonine) deaminase; catalyzes the degradation of both L-serine and L-threonine; required to use serine or threonine as the sole nitrogen source, transcriptionally induced by serine and threonine; Belongs to the serine/threonine dehydratase family.
      
 0.513
YBR121C-A
Uncharacterized protein YBR121C-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; completely contained within the verified gene GRS1; identified by expression profiling and mass spectrometry.
   
    0.448
YBR141W-A
Putative uncharacterized protein YBR141W-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps the uncharacterized ORF YBR141C; identified by gene-trapping, microarray analysis, and genome-wide homology searching.
   
    0.447
YHR073W-A
Uncharacterized protein YHR073W-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps verified ORF YHR073W; identified by expression profiling and mass spectrometry.
   
    0.426
YOL166W-A
UPF0320 protein YOL166W-A; Protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching; Belongs to the UPF0320 family.
   
    0.414
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: ATCC 18824, Candida robusta, Mycoderma cerevisiae, NRRL Y-12632, S. cerevisiae, Saccharomyces capensis, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, yeast
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