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ERS1 protein (Saccharomyces cerevisiae) - STRING interaction network
"ERS1" - Protein with similarity to human cystinosin, which is a H(+)-driven transporter involved in L-cystine export from lysosomes and implicated in the disease cystinosis in Saccharomyces cerevisiae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ERS1Protein with similarity to human cystinosin, which is a H(+)-driven transporter involved in L-cystine export from lysosomes and implicated in the disease cystinosis; contains seven transmembrane domains; Transport cystine out of vacuoles/endodomes (260 aa)    
Predicted Functional Partners:
MEH1
Component of the EGO and GSE complexes; EGO is involved in the regulation of microautophagy and GSE is required for proper sorting of amino acid permease Gap1p; loss results in a defect in vacuolar acidification; Component of the GSE complex, a GTPase complex required for intracellular sorting of GAP1 out of the endosome. Component of the EGO complex, a complex involved in the regulation of microautophagy (184 aa)
       
 
  0.947
ERD1
Predicted membrane protein required for lumenal ER protein retention; mutants secrete the endogenous ER protein, BiP (Kar2p); Required for the retention of luminal endoplasmic reticulum proteins, affects glycoprotein processing in the Golgi apparatus (362 aa)
       
 
  0.908
RBD2
Possible rhomboid protease, has similarity to eukaryotic rhomboid proteases including Pcp1p; Probable serine protease (262 aa)
       
      0.806
YPQ2
Putative protein of unknown function; May function as an amino acid transporter mediating the export of cationic amino acids from the vacuole (317 aa)
     
   
  0.767
YPQ1
Putative protein of unknown function; predicted to contain six transmembrane domains and is 58% similar to the uncharacterized ORF YBR147W; May function as an amino acid transporter mediating the export of cationic amino acids from the vacuole (308 aa)
     
   
  0.735
YCL002C
Putative protein of unknown function; YCL002C is not an essential gene (263 aa)
           
  0.698
RTC2
Protein of unknown function; mutant produces large lipid droplets, is resistant to fluconazole, has decreased levels of rDNA transcription, growth defects on minimal media, and suppresses cdc13-1; detected in highly purified mitochondria; similar to /.../rotein coupled receptor from S. pombe; May function as an amino acid transporter mediating the export of cationic amino acids from the vacuole. Required for optimal growth in synthetic medium (296 aa)
     
   
  0.696
YDR090C
Putative protein of unknown function (310 aa)
     
   
  0.665
VBA3
Permease of basic amino acids in the vacuolar membrane; Transporter required for vacuolar uptake of histidine and lysine (458 aa)
       
 
  0.615
YMR010W
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YMR010W is not an essential gene; YMR010W mRNA is transcribed with ADI1 (405 aa)
     
   
  0.611
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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