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OCA4 protein (Saccharomyces cerevisiae) - STRING interaction network
"OCA4" - Cytoplasmic protein required for replication of Brome mosaic virus in Saccharomyces cerevisiae
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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OCA4Cytoplasmic protein required for replication of Brome mosaic virus; S. cerevisiae is a model system for studying replication of positive-strand RNA viruses in their natural hosts; Required for replication of Brome mosaic virus (BMV) (362 aa)    
Predicted Functional Partners:
OCA2
Putative protein with similarity to predicted tyrosine phosphatases Oca1p and Siw14p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YNL056W is not an essential gene; Required for normal growth in the presence of linoleic acid hydroperoxide (LoaOOH) (197 aa)
       
 
  0.962
SIW14
Tyrosine phosphatase involved in actin organization and endocytosis; localized to the cytoplasm; Plays a role in actin filament organization and endocytosis (281 aa)
       
 
  0.958
OCA5
Cytoplasmic protein required for replication of Brome mosaic virus; S. cerevisiae is a model system for studying replication of positive-strand RNA viruses in their natural hosts; Required for replication of brome mosaic virus (BMV), a positive-strand RNA virus (679 aa)
       
 
  0.942
OCA1
Putative protein tyrosine phosphatase, required for cell cycle arrest in response to oxidative damage of DNA; Putative tyrosine-protein phosphatase required for protection against superoxide stress. Involved in cell-cycle delay in response to linoleic acid hydroperoxide (LoaOOH) (238 aa)
       
 
0.899
SSN8
Cyclin-like component of the RNA polymerase II holoenzyme, involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression and telomere maintenance; Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II- dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to fo [...] (323 aa)
       
      0.480
YKL050C
Protein of unknown function; the YKL050W protein is a target of the SCFCdc4 ubiquitin ligase complex and YKL050W transcription is regulated by Azf1p (922 aa)
           
  0.470
OCA6
Cytoplasmic protein required for replication of Brome mosaic virus; S. cerevisiae is a model system for studying positive-strand RNA virus replication; null mutation confers sensitivity to tunicamycin and DTT; Required for replication of Brome mosaic virus (BMV) (224 aa)
     
   
  0.469
YML009C-A
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data (108 aa)
           
  0.457
YGL042C
Dubious open reading frame, not conserved in closely related Saccharomyces species; deletion mutation blocks replication of Brome mosaic virus in S. cerevisiae, but this is likely due to effects on the overlapping gene DST1 (101 aa)
           
  0.441
YER119C-A
Dubious open reading frame, not conserved in closely related Saccharomyces species; deletion mutation blocks replication of Brome mosaic virus in S. cerevisiae, but this is likely due to effects on the overlapping gene SCS2 (123 aa)
           
  0.441
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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