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NHP10 protein (Saccharomyces cerevisiae) - STRING interaction network
"NHP10" - Non-essential INO80 chromatin remodeling complex subunit in Saccharomyces cerevisiae
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Predicted Interactions
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NHP10Non-essential INO80 chromatin remodeling complex subunit; preferentially binds DNA ends, protecting them from exonucleatic cleavage; deletion affects telomere maintenance via recombination; related to mammalian high mobility group proteins; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex (203 aa)    
Predicted Functional Partners:
INO80
ATPase and nucleosome spacing factor, subunit of complex containing actin and actin-related proteins that has chromatin remodeling activity and 3’ to 5’ DNA helicase activity in vitro; has a role in modulating stress gene transcription; Putative DNA helicase component of the INO80 complex which remodels chromatin by shifting nucleosomes. Its ability to induce transcription of some phosphate-responsive genes is modulated by inositol polyphosphates. The INO80 complex is involved in DNA repair by associating to ’Ser-129’ phosphorylated H2A histones as a response to DNA damage (1489 aa)
     
  0.996
IES3
Subunit of the INO80 chromatin remodeling complex; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin-remodeling complex (250 aa)
       
  0.996
RVB1
Essential protein involved in transcription regulation; component of chromatin remodeling complexes; required for assembly and function of the INO80 complex; also referred to as pontin; member of the RUVB-like protein family; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes. Its ability [...] (463 aa)
     
  0.995
RVB2
Essential protein involved in transcription regulation; component of chromatin remodeling complexes; required for assembly and function of the INO80 complex; also referred to as reptin; member of the RUVB-like protein family; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes. Its ability [...] (471 aa)
     
  0.994
IES1
Subunit of the INO80 chromatin remodeling complex; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin-remodeling complex (692 aa)
       
  0.993
ARP4
Nuclear actin-related protein involved in chromatin remodeling, component of chromatin-remodeling enzyme complexes; Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. ARP4 recognizes H2AS128ph (gamma-H2A) and is required for NuA4 complex integrity. Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional [...] (489 aa)
     
  0.993
ACT1
Actin, structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells (375 aa)
       
  0.991
ARP5
Nuclear actin-related protein involved in chromatin remodeling, component of chromatin-remodeling enzyme complexes; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex (755 aa)
       
  0.990
TAF14
Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes, involved in RNA polymerase II transcription initiation and in chromatin modification; contains a YEATS domain; Functions as a component of the DNA-binding general transcription factor complex TFIID, the RNA polymerase II associated general transcription factor complex TFIIF, and the chromatin-remodeling complex SWI/SNF. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II thro [...] (244 aa)
       
  0.990
IES5
Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions (125 aa)
       
  0.983
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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