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DIA3 protein (Saccharomyces cerevisiae) - STRING interaction network
"DIA3" - Protein of unknown function, involved in invasive and pseudohyphal growth in Saccharomyces cerevisiae
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
DIA3Protein of unknown function, involved in invasive and pseudohyphal growth (468 aa)    
Predicted Functional Partners:
THI80
Thiamine pyrophosphokinase, phosphorylates thiamine to produce the coenzyme thiamine pyrophosphate (thiamine diphosphate); Essential protein, it is the only enzyme in yeast capable of synthesizing thiamine pyrophosphate (TPP) (319 aa)
         
  0.904
THI6
Thiamine-phosphate diphosphorylase and hydroxyethylthiazole kinase; required for thiamine biosynthesis; GFP-fusion protein localizes to the cytoplasm in a punctate pattern; Essential for thiamine biosynthesis. The kinase activity is involved in the salvage synthesis of TH-P from the thiazole (540 aa)
         
    0.900
SER3
3-phosphoglycerate dehydrogenase, catalyzes the first step in serine and glycine biosynthesis; isozyme of Ser33p (469 aa)
       
 
  0.734
HSF1
Trimeric heat shock transcription factor, activates multiple genes in response to stresses that include hyperthermia; recognizes variable heat shock elements (HSEs) consisting of inverted NGAAN repeats; posttranslationally regulated; DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. Also required for growth at normal temperatures (833 aa)
       
      0.577
YPR071W
Putative membrane protein; YPR071W is not an essential gene (211 aa)
           
  0.572
PAU17
Protein of unknown function, member of the seripauperin multigene family encoded mainly in subtelomeric regions; YLL025W is not an essential gene (124 aa)
           
  0.544
SPO24
Protein of unknown function; transcription is regulated by Pdr1p (67 aa)
           
  0.519
DIA1
Protein of unknown function, involved in invasive and pseudohyphal growth; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; Involved in regulation of invasive growth (336 aa)
           
  0.519
YSC83
Non-essential mitochondrial protein of unknown function; mRNA induced during meiosis, peaking between mid to late prophase of meiosis I; similar to S. douglasii YSD83 (385 aa)
           
  0.511
CNE1
Calnexin; integral membrane ER chaperone involved in folding and quality control of glycoproteins; chaperone activity is inhibited by Mpd1p, with which Cne1p interacts; 24% identical to mammalian calnexin; Ca+ binding not yet shown in yeast; Interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins (502 aa)
       
 
  0.471
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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