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MRX9 protein (Saccharomyces cerevisiae) - STRING interaction network
"MRX9" - Putative protein of unknown function in Saccharomyces cerevisiae
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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MRX9Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YDL027C is not an essential gene; Component of MIOREX complexes, large expressome-like assemblies of ribosomes with factors involved in all the steps of post-transcriptional gene expression (420 aa)    
Predicted Functional Partners:
TRM732
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YMR259C is not an essential gene; Required together with TRM7 for the methylation of the 2’-O-ribose of cytidine at position 32 of the tRNA anticodon loop of tRNA(Phe) and tRNA(Leu(UAA)) (1420 aa)
           
  0.642
YJR030C
Putative protein of unknown function; expression repressed in carbon limited vs carbon replete chemostat cultures; YJR030C is a non-essential gene (745 aa)
           
  0.625
UBX3
UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p, green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; Involved in CDC48-dependent protein degradation through the ubiquitin/proteasome pathway. Involved in delivery of substrates to the 26S proteasome. Also required for membrane fusion (By similarity) (455 aa)
     
        0.623
SHE10
Putative glycosylphosphatidylinositol (GPI)-anchored protein of unknown function; overexpression causes growth arrest; Involved in spore wall assembly (PubMed-23966878). May be a component of the mitochondrial RNase MRP (MtMRP), a ribonucleoprotein endoribonuclease involved in the cleaving RNA transcripts to generate primers for DNA replication in mitochondria (PubMed-20086051). Causes growth arrest when highly overexpressed (PubMed-7762298) (577 aa)
           
  0.621
YFR006W
Putative X-Pro aminopeptidase; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YFR006W is not an essential gene (535 aa)
           
  0.579
YHR127W
Protein of unknown function; localizes to the nucleus; required for asymmetric localization of Kar9p during mitosis (243 aa)
           
  0.487
ETP1
Protein of unknown function required for growth on ethanol; contains a zinc finger region and has homology to human BRAP2, which is a cytoplasmic protein that binds nuclear localization sequences; May act as a cytoplasmic retention protein with a role in regulating nuclear transport. Binds nuclear localization sequences in vitro. Needed to adapt efficiently to ethanol, either as sole carbon source or as cell stressor. Involved in ethanol- dependent transcriptional activation of several genes and ethanol- induced protein turnover of some proteins (585 aa)
           
  0.485
TYW3
tRNA methyltransferase required for synthesis of wybutosine, a modified guanosine found at the 3’-position adjacent to the anticodon of phenylalanine tRNA which supports reading frame maintenance by stabilizing codon-anticodon interactions; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3’-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72 (273 aa)
           
  0.483
SNT2
DNA binding protein with similarity to the S. pombe Snt2 protein; computational analysis suggests a role in regulation of expression of genes encoding amine transporters; Transcriptional regulator that, together with ECM5, recruits histone deacetylase RPD3 to a small number of promoters of stress-response genes in response to oxidative stress (PubMed-23878396). Probable ubiquitin-protein ligase involved in the degradation-related ubiquitination of histones. Contributes to the post-translational regulation of histone protein levels by polyubiquitination of excess histones for subsequent [...] (1403 aa)
           
  0.483
CIR2
Putative ortholog of human electron transfer flavoprotein dehydrogenase (ETF-dH); found in a large supramolecular complex with other mitochondrial dehydrogenases; may have a role in oxidative stress response; Accepts electrons from ETF and reduces ubiquinone (631 aa)
           
  0.480
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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