Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
YDL172CPutative uncharacterized protein YDL172C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. (159 aa)    
Predicted Functional Partners:
YDL011C
Putative uncharacterized protein YDL011C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps the uncharacterized ORF YDL010W.
   
  
 0.871
YNL043C
Putative uncharacterized protein YNL043C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YIP3/YNL044W.
   
  
 0.869
YPR170C
Putative uncharacterized membrane protein YPR170C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps ORFs YPR169W-A and YPR170W-B.
   
  
 0.850
YMR007W
Uncharacterized protein YMR007W; Putative protein of unknown function; conserved among S. cerevisiae strains; YMR007W is not an essential gene.
   
  
 0.836
YGL165C
Putative uncharacterized protein YGL165C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF CUP2/YGL166W.
   
  
 0.830
MTC6
Protein of unknown function; mtc6 is synthetically sick with cdc13-1; SWAT-GFP and mCherry fusion proteins localize to the vacuole while SWAT-GFP fusion also localizes to the endoplasmic reticulum.
      
 0.810
PAR32
Protein of unknown function; hyperphosphorylated upon rapamycin treatment in a Tap42p-dependent manner; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; PAR32 is not an essential gene.
   
  
 0.766
YMR304C-A
Putative uncharacterized membrane protein YMR304C-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps 3' end of verified ORF SCW10/YMR305C.
   
  
 0.753
DLT1
Defect at low temperature protein 1; Protein of unknown function; mutant sensitive to 6-azauracil (6AU) and mycophenolic acid (MPA); Belongs to the DLT1 family.
      
 0.746
MTC2
Protein of unknown function; mtc2 is synthetically sick with cdc13-1; Belongs to the MTC2 family.
      
 0.734
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: ATCC 18824, Candida robusta, Mycoderma cerevisiae, NRRL Y-12632, S. cerevisiae, Saccharomyces capensis, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, yeast
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