STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ASF2Anti-silencing protein 2; Anti-silencing protein; causes derepression of silent loci when overexpressed (525 aa)    
Predicted Functional Partners:
YER039C-A
Putative protein of unknown function; YER039C-A is not an essential gene; Belongs to the TPT transporter family. SLC35D subfamily
      
 0.710
PAU11
Seripauperin-11; Putative protein of unknown function; member of the seripauperin multigene family encoded mainly in subtelomeric regions; mRNA expression appears to be regulated by SUT1 and UPC2; Belongs to the SRP1/TIP1 family. Seripauperin subfamily
      
 0.654
YGL081W
Uncharacterized protein YGL081W; Putative protein of unknown function; non-essential gene; interacts genetically with CHS5, a gene involved in chitin biosynthesis
      
 0.651
DDI3
Cyanamide hydratase that detoxifies cyanamide; member of the HD domain metalloprotein superfamily; expression is induced over 100-fold by cyanamide and by SN2-type DNA alkylating agents such as MMS and DMA; induction decreased in rad6 and rad18 mutants; gene and protein are identical to DDI2 and Ddi2p
      
 0.651
HVG1
Probable GDP-mannose transporter 2; Protein of unknown function; HVG1 has a paralog, VRG4, that arose from the whole genome duplication
      
 0.650
YIL165C
Putative protein of unknown function; mutant exhibits mitophagy defects; in closely related species and other S. cerevisiae strain backgrounds YIL165C and adjacent ORF, YIL164C, likely constitute a single ORF encoding a nitrilase gene; Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family
      
 0.650
YOL162W
Putative uncharacterized transporter YOL162W; Putative protein of unknown function; member of the Dal5p subfamily of the major facilitator family
      
 0.616
ECM31
3-methyl-2-oxobutanoate hydroxymethyltransferase; Ketopantoate hydroxymethyltransferase; required for pantothenic acid biosynthesis, converts 2-oxoisovalerate into 2-dehydropantoate
      
 0.615
KTR7
Probable mannosyltransferase KTR7; Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family; KTR7 has a paralog, KTR5, that arose from the whole genome duplication
      
 0.615
YOL163W
Putative uncharacterized transporter YOL163W; Putative protein of unknown function; member of the Dal5p subfamily of the major facilitator family
      
 0.614
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: ATCC 18824, Candida robusta, NRRL Y-12632, S. cerevisiae, Saccharomyces capensis, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.