| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CAP1 | YDL211C | YKL007W | YDL211C | Alpha subunit of the capping protein heterodimer (Cap1p and Cap2p); capping protein (CP) binds to the barbed ends of actin filaments preventing further polymerization; localized predominantly to cortical actin patches; protein increases in abundance and relocalizes from bud neck to plasma membrane upon DNA replication stress. | Uncharacterized protein YDL211C; Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; YDL211C has a paralog, TDA7, that arose from the whole genome duplication. | 0.755 |
| EHD3 | MRPL28 | YDR036C | YDR462W | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; 3-hydroxyisobutyryl-CoA hydrolase; member of a family of enoyl-CoA hydratase/isomerases; non-tagged protein is detected in highly purified mitochondria in high-throughput studies; phosphorylated; mutation affects fluid-phase endocytosis. | Mitochondrial ribosomal protein of the large subunit; protein abundance increases in response to DNA replication stress. | 0.939 |
| EHD3 | MRPL39 | YDR036C | YML009C | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; 3-hydroxyisobutyryl-CoA hydrolase; member of a family of enoyl-CoA hydratase/isomerases; non-tagged protein is detected in highly purified mitochondria in high-throughput studies; phosphorylated; mutation affects fluid-phase endocytosis. | Mitochondrial ribosomal protein of the large subunit. | 0.989 |
| EHD3 | TTI2 | YDR036C | YJR136C | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; 3-hydroxyisobutyryl-CoA hydrolase; member of a family of enoyl-CoA hydratase/isomerases; non-tagged protein is detected in highly purified mitochondria in high-throughput studies; phosphorylated; mutation affects fluid-phase endocytosis. | TEL2-interacting protein 2; Subunit of the ASTRA complex, involved in chromatin remodeling; telomere length regulator involved in the stability or biogenesis of PIKKs such as TORC1; involved in the cellular stress response; similar to S. pombe Tti2p; may interact with Rsm23p; GFP-fusion protein localizes to the cytoplasm. | 0.452 |
| EHD3 | YDL211C | YDR036C | YDL211C | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; 3-hydroxyisobutyryl-CoA hydrolase; member of a family of enoyl-CoA hydratase/isomerases; non-tagged protein is detected in highly purified mitochondria in high-throughput studies; phosphorylated; mutation affects fluid-phase endocytosis. | Uncharacterized protein YDL211C; Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; YDL211C has a paralog, TDA7, that arose from the whole genome duplication. | 0.630 |
| EHD3 | YDL218W | YDR036C | YDL218W | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; 3-hydroxyisobutyryl-CoA hydrolase; member of a family of enoyl-CoA hydratase/isomerases; non-tagged protein is detected in highly purified mitochondria in high-throughput studies; phosphorylated; mutation affects fluid-phase endocytosis. | Putative protein of unknown function; YDL218W transcription is regulated by Azf1p and induced by starvation and aerobic conditions; expression also induced in cells treated with the mycotoxin patulin. | 0.500 |
| EHD3 | YDR476C | YDR036C | YDR476C | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; 3-hydroxyisobutyryl-CoA hydrolase; member of a family of enoyl-CoA hydratase/isomerases; non-tagged protein is detected in highly purified mitochondria in high-throughput studies; phosphorylated; mutation affects fluid-phase endocytosis. | Uncharacterized protein YDR476C; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YDR476C is not an essential gene. | 0.572 |
| EHD3 | YNL320W | YDR036C | YNL320W | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; 3-hydroxyisobutyryl-CoA hydrolase; member of a family of enoyl-CoA hydratase/isomerases; non-tagged protein is detected in highly purified mitochondria in high-throughput studies; phosphorylated; mutation affects fluid-phase endocytosis. | Uncharacterized membrane protein YNL320W; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; To S.pombe bem46 and M.tuberculosis Rv2307c. | 0.559 |
| MRPL28 | EHD3 | YDR462W | YDR036C | Mitochondrial ribosomal protein of the large subunit; protein abundance increases in response to DNA replication stress. | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; 3-hydroxyisobutyryl-CoA hydrolase; member of a family of enoyl-CoA hydratase/isomerases; non-tagged protein is detected in highly purified mitochondria in high-throughput studies; phosphorylated; mutation affects fluid-phase endocytosis. | 0.939 |
| MRPL28 | MRPL39 | YDR462W | YML009C | Mitochondrial ribosomal protein of the large subunit; protein abundance increases in response to DNA replication stress. | Mitochondrial ribosomal protein of the large subunit. | 0.995 |
| MRPL28 | YDL211C | YDR462W | YDL211C | Mitochondrial ribosomal protein of the large subunit; protein abundance increases in response to DNA replication stress. | Uncharacterized protein YDL211C; Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; YDL211C has a paralog, TDA7, that arose from the whole genome duplication. | 0.536 |
| MRPL28 | YDR476C | YDR462W | YDR476C | Mitochondrial ribosomal protein of the large subunit; protein abundance increases in response to DNA replication stress. | Uncharacterized protein YDR476C; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YDR476C is not an essential gene. | 0.476 |
| MRPL39 | EHD3 | YML009C | YDR036C | Mitochondrial ribosomal protein of the large subunit. | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; 3-hydroxyisobutyryl-CoA hydrolase; member of a family of enoyl-CoA hydratase/isomerases; non-tagged protein is detected in highly purified mitochondria in high-throughput studies; phosphorylated; mutation affects fluid-phase endocytosis. | 0.989 |
| MRPL39 | MRPL28 | YML009C | YDR462W | Mitochondrial ribosomal protein of the large subunit. | Mitochondrial ribosomal protein of the large subunit; protein abundance increases in response to DNA replication stress. | 0.995 |
| MRPL39 | SUV3 | YML009C | YPL029W | Mitochondrial ribosomal protein of the large subunit. | ATP-dependent RNA helicase; component of the mitochondrial degradosome along with the RNase Dss1p; the degradosome associates with the ribosome and mediates RNA turnover; also required during splicing of the COX1 AI5_beta intron; expression of a processed form of human homolog SUPV3L1 carrying an N-terminal deletion of 46 amino acids rescues yeast suv3 null mutant. | 0.481 |
| MRPL39 | TTI2 | YML009C | YJR136C | Mitochondrial ribosomal protein of the large subunit. | TEL2-interacting protein 2; Subunit of the ASTRA complex, involved in chromatin remodeling; telomere length regulator involved in the stability or biogenesis of PIKKs such as TORC1; involved in the cellular stress response; similar to S. pombe Tti2p; may interact with Rsm23p; GFP-fusion protein localizes to the cytoplasm. | 0.448 |
| MRPL39 | YDL211C | YML009C | YDL211C | Mitochondrial ribosomal protein of the large subunit. | Uncharacterized protein YDL211C; Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; YDL211C has a paralog, TDA7, that arose from the whole genome duplication. | 0.605 |
| MRPL39 | YDL218W | YML009C | YDL218W | Mitochondrial ribosomal protein of the large subunit. | Putative protein of unknown function; YDL218W transcription is regulated by Azf1p and induced by starvation and aerobic conditions; expression also induced in cells treated with the mycotoxin patulin. | 0.418 |
| MRPL39 | YDR476C | YML009C | YDR476C | Mitochondrial ribosomal protein of the large subunit. | Uncharacterized protein YDR476C; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YDR476C is not an essential gene. | 0.538 |
| MRPL39 | YNL320W | YML009C | YNL320W | Mitochondrial ribosomal protein of the large subunit. | Uncharacterized membrane protein YNL320W; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; To S.pombe bem46 and M.tuberculosis Rv2307c. | 0.445 |