node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AIM19 | AIM6 | YIL087C | YDL237W | Protein of unknown function; mitochondrial protein that physically interacts with Tim23p; null mutant displays reduced respiratory growth; Belongs to the AIM19 family. | Altered inheritance of mitochondria protein 6; Protein of unknown function; required for respiratory growth; YDL237W is not an essential gene. | 0.549 |
AIM2 | AIM3 | YAL049C | YBR108W | Cytoplasmic protein involved in mitochondrial function or organization; null mutant displays reduced frequency of mitochondrial genome loss; potential Hsp82p interactor; Belongs to the AIM2 family. | Altered inheritance of mitochondria protein 3; Protein that inhibits barbed-end actin filament elongation; interacts with Rvs167p; null mutant is viable and displays elevated frequency of mitochondrial genome loss; Belongs to the AIM3 family. | 0.776 |
AIM2 | AIM4 | YAL049C | YBR194W | Cytoplasmic protein involved in mitochondrial function or organization; null mutant displays reduced frequency of mitochondrial genome loss; potential Hsp82p interactor; Belongs to the AIM2 family. | Altered inheritance of mitochondria protein 4; Protein proposed to be associated with the nuclear pore complex; null mutant is viable, displays elevated frequency of mitochondrial genome loss and is sensitive to freeze-thaw stress; Belongs to the AIM4 family. | 0.536 |
AIM2 | AIM6 | YAL049C | YDL237W | Cytoplasmic protein involved in mitochondrial function or organization; null mutant displays reduced frequency of mitochondrial genome loss; potential Hsp82p interactor; Belongs to the AIM2 family. | Altered inheritance of mitochondria protein 6; Protein of unknown function; required for respiratory growth; YDL237W is not an essential gene. | 0.616 |
AIM2 | AIM7 | YAL049C | YDR063W | Cytoplasmic protein involved in mitochondrial function or organization; null mutant displays reduced frequency of mitochondrial genome loss; potential Hsp82p interactor; Belongs to the AIM2 family. | Protein that interacts with Arp2/3 complex; interacts with Arp2/3 complex to stimulate actin filament debranching and inhibit actin nucleation; has similarity to Cof1p and also to human glia maturation factor (GMF); null mutant displays elevated mitochondrial genome loss; Belongs to the actin-binding proteins ADF family. GMF subfamily. | 0.487 |
AIM2 | AIM9 | YAL049C | YER080W | Cytoplasmic protein involved in mitochondrial function or organization; null mutant displays reduced frequency of mitochondrial genome loss; potential Hsp82p interactor; Belongs to the AIM2 family. | Altered inheritance of mitochondria protein 9, mitochondrial; Protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays elevated frequency of mitochondrial genome loss. | 0.708 |
AIM3 | AIM2 | YBR108W | YAL049C | Altered inheritance of mitochondria protein 3; Protein that inhibits barbed-end actin filament elongation; interacts with Rvs167p; null mutant is viable and displays elevated frequency of mitochondrial genome loss; Belongs to the AIM3 family. | Cytoplasmic protein involved in mitochondrial function or organization; null mutant displays reduced frequency of mitochondrial genome loss; potential Hsp82p interactor; Belongs to the AIM2 family. | 0.776 |
AIM3 | AIM4 | YBR108W | YBR194W | Altered inheritance of mitochondria protein 3; Protein that inhibits barbed-end actin filament elongation; interacts with Rvs167p; null mutant is viable and displays elevated frequency of mitochondrial genome loss; Belongs to the AIM3 family. | Altered inheritance of mitochondria protein 4; Protein proposed to be associated with the nuclear pore complex; null mutant is viable, displays elevated frequency of mitochondrial genome loss and is sensitive to freeze-thaw stress; Belongs to the AIM4 family. | 0.791 |
AIM3 | AIM6 | YBR108W | YDL237W | Altered inheritance of mitochondria protein 3; Protein that inhibits barbed-end actin filament elongation; interacts with Rvs167p; null mutant is viable and displays elevated frequency of mitochondrial genome loss; Belongs to the AIM3 family. | Altered inheritance of mitochondria protein 6; Protein of unknown function; required for respiratory growth; YDL237W is not an essential gene. | 0.729 |
AIM3 | AIM7 | YBR108W | YDR063W | Altered inheritance of mitochondria protein 3; Protein that inhibits barbed-end actin filament elongation; interacts with Rvs167p; null mutant is viable and displays elevated frequency of mitochondrial genome loss; Belongs to the AIM3 family. | Protein that interacts with Arp2/3 complex; interacts with Arp2/3 complex to stimulate actin filament debranching and inhibit actin nucleation; has similarity to Cof1p and also to human glia maturation factor (GMF); null mutant displays elevated mitochondrial genome loss; Belongs to the actin-binding proteins ADF family. GMF subfamily. | 0.697 |
AIM3 | AIM9 | YBR108W | YER080W | Altered inheritance of mitochondria protein 3; Protein that inhibits barbed-end actin filament elongation; interacts with Rvs167p; null mutant is viable and displays elevated frequency of mitochondrial genome loss; Belongs to the AIM3 family. | Altered inheritance of mitochondria protein 9, mitochondrial; Protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays elevated frequency of mitochondrial genome loss. | 0.564 |
AIM3 | MIC12 | YBR108W | YBR262C | Altered inheritance of mitochondria protein 3; Protein that inhibits barbed-end actin filament elongation; interacts with Rvs167p; null mutant is viable and displays elevated frequency of mitochondrial genome loss; Belongs to the AIM3 family. | Component of the MICOS complex; MICOS (formerly MINOS or MitOS) is a mitochondrial inner membrane complex that extends into the intermembrane space and has a role in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane; forms a subcomplex with Mic10p and Mic27p whose assembly and stability requires cardiolipin. | 0.471 |
AIM4 | AIM2 | YBR194W | YAL049C | Altered inheritance of mitochondria protein 4; Protein proposed to be associated with the nuclear pore complex; null mutant is viable, displays elevated frequency of mitochondrial genome loss and is sensitive to freeze-thaw stress; Belongs to the AIM4 family. | Cytoplasmic protein involved in mitochondrial function or organization; null mutant displays reduced frequency of mitochondrial genome loss; potential Hsp82p interactor; Belongs to the AIM2 family. | 0.536 |
AIM4 | AIM3 | YBR194W | YBR108W | Altered inheritance of mitochondria protein 4; Protein proposed to be associated with the nuclear pore complex; null mutant is viable, displays elevated frequency of mitochondrial genome loss and is sensitive to freeze-thaw stress; Belongs to the AIM4 family. | Altered inheritance of mitochondria protein 3; Protein that inhibits barbed-end actin filament elongation; interacts with Rvs167p; null mutant is viable and displays elevated frequency of mitochondrial genome loss; Belongs to the AIM3 family. | 0.791 |
AIM4 | AIM6 | YBR194W | YDL237W | Altered inheritance of mitochondria protein 4; Protein proposed to be associated with the nuclear pore complex; null mutant is viable, displays elevated frequency of mitochondrial genome loss and is sensitive to freeze-thaw stress; Belongs to the AIM4 family. | Altered inheritance of mitochondria protein 6; Protein of unknown function; required for respiratory growth; YDL237W is not an essential gene. | 0.604 |
AIM4 | AIM7 | YBR194W | YDR063W | Altered inheritance of mitochondria protein 4; Protein proposed to be associated with the nuclear pore complex; null mutant is viable, displays elevated frequency of mitochondrial genome loss and is sensitive to freeze-thaw stress; Belongs to the AIM4 family. | Protein that interacts with Arp2/3 complex; interacts with Arp2/3 complex to stimulate actin filament debranching and inhibit actin nucleation; has similarity to Cof1p and also to human glia maturation factor (GMF); null mutant displays elevated mitochondrial genome loss; Belongs to the actin-binding proteins ADF family. GMF subfamily. | 0.532 |
AIM4 | AIM9 | YBR194W | YER080W | Altered inheritance of mitochondria protein 4; Protein proposed to be associated with the nuclear pore complex; null mutant is viable, displays elevated frequency of mitochondrial genome loss and is sensitive to freeze-thaw stress; Belongs to the AIM4 family. | Altered inheritance of mitochondria protein 9, mitochondrial; Protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays elevated frequency of mitochondrial genome loss. | 0.697 |
AIM4 | MIC12 | YBR194W | YBR262C | Altered inheritance of mitochondria protein 4; Protein proposed to be associated with the nuclear pore complex; null mutant is viable, displays elevated frequency of mitochondrial genome loss and is sensitive to freeze-thaw stress; Belongs to the AIM4 family. | Component of the MICOS complex; MICOS (formerly MINOS or MitOS) is a mitochondrial inner membrane complex that extends into the intermembrane space and has a role in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane; forms a subcomplex with Mic10p and Mic27p whose assembly and stability requires cardiolipin. | 0.618 |
AIM6 | AIM19 | YDL237W | YIL087C | Altered inheritance of mitochondria protein 6; Protein of unknown function; required for respiratory growth; YDL237W is not an essential gene. | Protein of unknown function; mitochondrial protein that physically interacts with Tim23p; null mutant displays reduced respiratory growth; Belongs to the AIM19 family. | 0.549 |
AIM6 | AIM2 | YDL237W | YAL049C | Altered inheritance of mitochondria protein 6; Protein of unknown function; required for respiratory growth; YDL237W is not an essential gene. | Cytoplasmic protein involved in mitochondrial function or organization; null mutant displays reduced frequency of mitochondrial genome loss; potential Hsp82p interactor; Belongs to the AIM2 family. | 0.616 |