node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AIM34 | MRX9 | YMR003W | YDL027C | Altered inheritance of mitochondria protein 34, mitochondrial; Protein of unknown function; GFP-fusion protein localizes to the mitochondria; null mutant is viable and displays reduced frequency of mitochondrial genome loss. | MIOREX complex component 9; Protein that associates with mitochondrial ribosome; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YDL027C is not an essential gene. | 0.699 |
AIM34 | YDL242W | YMR003W | YDL242W | Altered inheritance of mitochondria protein 34, mitochondrial; Protein of unknown function; GFP-fusion protein localizes to the mitochondria; null mutant is viable and displays reduced frequency of mitochondrial genome loss. | Uncharacterized protein YDL242W; Putative protein of unknown function; conserved across S. cerevisiae strains. | 0.609 |
AIM34 | YDR286C | YMR003W | YDR286C | Altered inheritance of mitochondria protein 34, mitochondrial; Protein of unknown function; GFP-fusion protein localizes to the mitochondria; null mutant is viable and displays reduced frequency of mitochondrial genome loss. | Glutaredoxin-like protein YDR286C; Putative protein of unknown function; predicted to have thiol-disulfide oxidoreductase active site; Belongs to the glutaredoxin family. YDR286C subfamily. | 0.487 |
MRX9 | AIM34 | YDL027C | YMR003W | MIOREX complex component 9; Protein that associates with mitochondrial ribosome; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YDL027C is not an essential gene. | Altered inheritance of mitochondria protein 34, mitochondrial; Protein of unknown function; GFP-fusion protein localizes to the mitochondria; null mutant is viable and displays reduced frequency of mitochondrial genome loss. | 0.699 |
MRX9 | YDL242W | YDL027C | YDL242W | MIOREX complex component 9; Protein that associates with mitochondrial ribosome; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YDL027C is not an essential gene. | Uncharacterized protein YDL242W; Putative protein of unknown function; conserved across S. cerevisiae strains. | 0.692 |
MRX9 | YDR286C | YDL027C | YDR286C | MIOREX complex component 9; Protein that associates with mitochondrial ribosome; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YDL027C is not an essential gene. | Glutaredoxin-like protein YDR286C; Putative protein of unknown function; predicted to have thiol-disulfide oxidoreductase active site; Belongs to the glutaredoxin family. YDR286C subfamily. | 0.837 |
MXR1 | MXR2 | YER042W | YCL033C | Methionine-S-sulfoxide reductase; involved in the response to oxidative stress; protects iron-sulfur clusters from oxidative inactivation along with MXR2; involved in the regulation of lifespan; reduced activity of human homolog implicated in Alzheimer disease. | Methionine-R-sulfoxide reductase; involved in the response to oxidative stress; protects iron-sulfur clusters from oxidative inactivation along with MXR1; involved in the regulation of lifespan. | 0.999 |
MXR1 | YDL242W | YER042W | YDL242W | Methionine-S-sulfoxide reductase; involved in the response to oxidative stress; protects iron-sulfur clusters from oxidative inactivation along with MXR2; involved in the regulation of lifespan; reduced activity of human homolog implicated in Alzheimer disease. | Uncharacterized protein YDL242W; Putative protein of unknown function; conserved across S. cerevisiae strains. | 0.478 |
MXR1 | YKL069W | YER042W | YKL069W | Methionine-S-sulfoxide reductase; involved in the response to oxidative stress; protects iron-sulfur clusters from oxidative inactivation along with MXR2; involved in the regulation of lifespan; reduced activity of human homolog implicated in Alzheimer disease. | Methionine-R-sulfoxide reductase; reduces the R enantiomer of free Met-SO, in contrast to Ycl033Cp which reduces Met-R-SO in a peptide linkage; has a role in protection against oxidative stress; relative distribution to the nucleus increases upon DNA replication stress. | 0.964 |
MXR1 | YOL118C | YER042W | YOL118C | Methionine-S-sulfoxide reductase; involved in the response to oxidative stress; protects iron-sulfur clusters from oxidative inactivation along with MXR2; involved in the regulation of lifespan; reduced activity of human homolog implicated in Alzheimer disease. | Uncharacterized protein YOL118C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | 0.540 |
MXR2 | MXR1 | YCL033C | YER042W | Methionine-R-sulfoxide reductase; involved in the response to oxidative stress; protects iron-sulfur clusters from oxidative inactivation along with MXR1; involved in the regulation of lifespan. | Methionine-S-sulfoxide reductase; involved in the response to oxidative stress; protects iron-sulfur clusters from oxidative inactivation along with MXR2; involved in the regulation of lifespan; reduced activity of human homolog implicated in Alzheimer disease. | 0.999 |
MXR2 | YDL242W | YCL033C | YDL242W | Methionine-R-sulfoxide reductase; involved in the response to oxidative stress; protects iron-sulfur clusters from oxidative inactivation along with MXR1; involved in the regulation of lifespan. | Uncharacterized protein YDL242W; Putative protein of unknown function; conserved across S. cerevisiae strains. | 0.597 |
MXR2 | YKL069W | YCL033C | YKL069W | Methionine-R-sulfoxide reductase; involved in the response to oxidative stress; protects iron-sulfur clusters from oxidative inactivation along with MXR1; involved in the regulation of lifespan. | Methionine-R-sulfoxide reductase; reduces the R enantiomer of free Met-SO, in contrast to Ycl033Cp which reduces Met-R-SO in a peptide linkage; has a role in protection against oxidative stress; relative distribution to the nucleus increases upon DNA replication stress. | 0.944 |
MXR2 | YOL118C | YCL033C | YOL118C | Methionine-R-sulfoxide reductase; involved in the response to oxidative stress; protects iron-sulfur clusters from oxidative inactivation along with MXR1; involved in the regulation of lifespan. | Uncharacterized protein YOL118C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | 0.692 |
YBR032W | YBR144C | YBR032W | YBR144C | Uncharacterized protein YBR032W; Putative protein of unknown function; conserved among S. cerevisiae strains; YBR032W is not an essential gene. | Uncharacterized protein YBR144C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; YBR144C is not an essential gene. | 0.768 |
YBR032W | YDL242W | YBR032W | YDL242W | Uncharacterized protein YBR032W; Putative protein of unknown function; conserved among S. cerevisiae strains; YBR032W is not an essential gene. | Uncharacterized protein YDL242W; Putative protein of unknown function; conserved across S. cerevisiae strains. | 0.872 |
YBR144C | YBR032W | YBR144C | YBR032W | Uncharacterized protein YBR144C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; YBR144C is not an essential gene. | Uncharacterized protein YBR032W; Putative protein of unknown function; conserved among S. cerevisiae strains; YBR032W is not an essential gene. | 0.768 |
YBR144C | YDL242W | YBR144C | YDL242W | Uncharacterized protein YBR144C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; YBR144C is not an essential gene. | Uncharacterized protein YDL242W; Putative protein of unknown function; conserved across S. cerevisiae strains. | 0.806 |
YDL242W | AIM34 | YDL242W | YMR003W | Uncharacterized protein YDL242W; Putative protein of unknown function; conserved across S. cerevisiae strains. | Altered inheritance of mitochondria protein 34, mitochondrial; Protein of unknown function; GFP-fusion protein localizes to the mitochondria; null mutant is viable and displays reduced frequency of mitochondrial genome loss. | 0.609 |
YDL242W | MRX9 | YDL242W | YDL027C | Uncharacterized protein YDL242W; Putative protein of unknown function; conserved across S. cerevisiae strains. | MIOREX complex component 9; Protein that associates with mitochondrial ribosome; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YDL027C is not an essential gene. | 0.692 |