| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARP1 | ARP4 | YHR129C | YJL081C | Centractin; Actin-related protein of the dynactin complex; required for spindle orientation and nuclear migration; forms actin-like short filament composed of 9 or 10 Arp1p monomers; putative ortholog of mammalian centractin. | Nuclear actin-related protein involved in chromatin remodeling; component of chromatin-remodeling enzyme complexes. | 0.936 |
| ARP1 | FYV1 | YHR129C | YDR024W | Centractin; Actin-related protein of the dynactin complex; required for spindle orientation and nuclear migration; forms actin-like short filament composed of 9 or 10 Arp1p monomers; putative ortholog of mammalian centractin. | Putative uncharacterized protein FYV1; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; not conserved in closely related Saccharomyces species; mutation decreases survival upon exposure to K1 killer toxin. | 0.471 |
| ARP4 | ARP1 | YJL081C | YHR129C | Nuclear actin-related protein involved in chromatin remodeling; component of chromatin-remodeling enzyme complexes. | Centractin; Actin-related protein of the dynactin complex; required for spindle orientation and nuclear migration; forms actin-like short filament composed of 9 or 10 Arp1p monomers; putative ortholog of mammalian centractin. | 0.936 |
| ARP4 | FYV1 | YJL081C | YDR024W | Nuclear actin-related protein involved in chromatin remodeling; component of chromatin-remodeling enzyme complexes. | Putative uncharacterized protein FYV1; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; not conserved in closely related Saccharomyces species; mutation decreases survival upon exposure to K1 killer toxin. | 0.410 |
| CAF120 | FYV1 | YNL278W | YDR024W | Part of the CCR4-NOT transcriptional regulatory complex; involved in controlling mRNA initiation, elongation, and degradation; contains a PH-like domain; CAF120 has a paralog, SKG3, that arose from the whole genome duplication. | Putative uncharacterized protein FYV1; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; not conserved in closely related Saccharomyces species; mutation decreases survival upon exposure to K1 killer toxin. | 0.540 |
| FYV1 | ARP1 | YDR024W | YHR129C | Putative uncharacterized protein FYV1; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; not conserved in closely related Saccharomyces species; mutation decreases survival upon exposure to K1 killer toxin. | Centractin; Actin-related protein of the dynactin complex; required for spindle orientation and nuclear migration; forms actin-like short filament composed of 9 or 10 Arp1p monomers; putative ortholog of mammalian centractin. | 0.471 |
| FYV1 | ARP4 | YDR024W | YJL081C | Putative uncharacterized protein FYV1; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; not conserved in closely related Saccharomyces species; mutation decreases survival upon exposure to K1 killer toxin. | Nuclear actin-related protein involved in chromatin remodeling; component of chromatin-remodeling enzyme complexes. | 0.410 |
| FYV1 | CAF120 | YDR024W | YNL278W | Putative uncharacterized protein FYV1; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; not conserved in closely related Saccharomyces species; mutation decreases survival upon exposure to K1 killer toxin. | Part of the CCR4-NOT transcriptional regulatory complex; involved in controlling mRNA initiation, elongation, and degradation; contains a PH-like domain; CAF120 has a paralog, SKG3, that arose from the whole genome duplication. | 0.540 |
| FYV1 | FYV5 | YDR024W | YCL058C | Putative uncharacterized protein FYV1; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; not conserved in closely related Saccharomyces species; mutation decreases survival upon exposure to K1 killer toxin. | Protein involved in regulation of the mating pathway; binds with Matalpha2p to promoters of haploid-specific genes; required for survival upon exposure to K1 killer toxin; involved in ion homeostasis. | 0.412 |
| FYV1 | ISY1 | YDR024W | YJR050W | Putative uncharacterized protein FYV1; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; not conserved in closely related Saccharomyces species; mutation decreases survival upon exposure to K1 killer toxin. | Pre-mRNA-splicing factor ISY1; Member of the NineTeen Complex (NTC); NTC contains Prp19p and stabilizes U6 snRNA in catalytic forms of spliceosome containing U2, U5, and U6 snRNAs; interacts with Prp16p to modulate splicing fidelity; isy1 syf2 cells have defective spindles. | 0.470 |
| FYV5 | FYV1 | YCL058C | YDR024W | Protein involved in regulation of the mating pathway; binds with Matalpha2p to promoters of haploid-specific genes; required for survival upon exposure to K1 killer toxin; involved in ion homeostasis. | Putative uncharacterized protein FYV1; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; not conserved in closely related Saccharomyces species; mutation decreases survival upon exposure to K1 killer toxin. | 0.412 |
| ISY1 | FYV1 | YJR050W | YDR024W | Pre-mRNA-splicing factor ISY1; Member of the NineTeen Complex (NTC); NTC contains Prp19p and stabilizes U6 snRNA in catalytic forms of spliceosome containing U2, U5, and U6 snRNAs; interacts with Prp16p to modulate splicing fidelity; isy1 syf2 cells have defective spindles. | Putative uncharacterized protein FYV1; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; not conserved in closely related Saccharomyces species; mutation decreases survival upon exposure to K1 killer toxin. | 0.470 |