node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RPB5 | RPC10 | YBR154C | YHR143W-A | RNA polymerase subunit ABC27; common to RNA polymerases I, II, and III; contacts DNA and affects transactivation; Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. | RNA polymerase subunit ABC10-alpha, found in RNA pol I, II, and III; relocalizes from nucleolus to cytoplasm upon DNA replication stress. | 0.999 |
RPB5 | RPC11 | YBR154C | YDR045C | RNA polymerase subunit ABC27; common to RNA polymerases I, II, and III; contacts DNA and affects transactivation; Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. | RNA polymerase III subunit C11; mediates pol III RNA cleavage activity and is important for termination of transcription; homologous to TFIIS. | 0.999 |
RPB5 | RPC17 | YBR154C | YJL011C | RNA polymerase subunit ABC27; common to RNA polymerases I, II, and III; contacts DNA and affects transactivation; Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. | RNA polymerase III subunit C17; physically interacts with C31, C11, and TFIIIB70; may be involved in the recruitment of pol III by the preinitiation complex; protein abundance increases in response to DNA replication stress; relocalizes to the cytosol in response to hypoxia. | 0.999 |
RPB5 | RPC19 | YBR154C | YNL113W | RNA polymerase subunit ABC27; common to RNA polymerases I, II, and III; contacts DNA and affects transactivation; Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. | RNA polymerase subunit AC19; common to RNA polymerases I and III. | 0.999 |
RPB5 | RPC25 | YBR154C | YKL144C | RNA polymerase subunit ABC27; common to RNA polymerases I, II, and III; contacts DNA and affects transactivation; Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. | RNA polymerase III subunit C25; required for transcription initiation; forms a heterodimer with Rpc17p; paralog of Rpb7p. | 0.999 |
RPB5 | RPC31 | YBR154C | YNL151C | RNA polymerase subunit ABC27; common to RNA polymerases I, II, and III; contacts DNA and affects transactivation; Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. | RNA polymerase III subunit C31; Belongs to the eukaryotic RPC7 RNA polymerase subunit family. | 0.999 |
RPB5 | RPC34 | YBR154C | YNR003C | RNA polymerase subunit ABC27; common to RNA polymerases I, II, and III; contacts DNA and affects transactivation; Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. | RNA polymerase III subunit C34; interacts with TFIIIB70 and is a key determinant in pol III recruitment by the preinitiation complex; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. | 0.999 |
RPB5 | RPC37 | YBR154C | YKR025W | RNA polymerase subunit ABC27; common to RNA polymerases I, II, and III; contacts DNA and affects transactivation; Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. | RNA polymerase III subunit C37. | 0.999 |
RPB5 | RPC53 | YBR154C | YDL150W | RNA polymerase subunit ABC27; common to RNA polymerases I, II, and III; contacts DNA and affects transactivation; Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. | RNA polymerase III subunit C53; Belongs to the eukaryotic RPC4/POLR3D RNA polymerase subunit family. | 0.999 |
RPB5 | RPO31 | YBR154C | YOR116C | RNA polymerase subunit ABC27; common to RNA polymerases I, II, and III; contacts DNA and affects transactivation; Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. | RNA polymerase III largest subunit C160; part of core enzyme; similar to bacterial beta-prime subunit and to RPA190 and RPO21; Belongs to the RNA polymerase beta' chain family. | 0.999 |
RPC10 | RPB5 | YHR143W-A | YBR154C | RNA polymerase subunit ABC10-alpha, found in RNA pol I, II, and III; relocalizes from nucleolus to cytoplasm upon DNA replication stress. | RNA polymerase subunit ABC27; common to RNA polymerases I, II, and III; contacts DNA and affects transactivation; Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. | 0.999 |
RPC10 | RPC11 | YHR143W-A | YDR045C | RNA polymerase subunit ABC10-alpha, found in RNA pol I, II, and III; relocalizes from nucleolus to cytoplasm upon DNA replication stress. | RNA polymerase III subunit C11; mediates pol III RNA cleavage activity and is important for termination of transcription; homologous to TFIIS. | 0.999 |
RPC10 | RPC17 | YHR143W-A | YJL011C | RNA polymerase subunit ABC10-alpha, found in RNA pol I, II, and III; relocalizes from nucleolus to cytoplasm upon DNA replication stress. | RNA polymerase III subunit C17; physically interacts with C31, C11, and TFIIIB70; may be involved in the recruitment of pol III by the preinitiation complex; protein abundance increases in response to DNA replication stress; relocalizes to the cytosol in response to hypoxia. | 0.999 |
RPC10 | RPC19 | YHR143W-A | YNL113W | RNA polymerase subunit ABC10-alpha, found in RNA pol I, II, and III; relocalizes from nucleolus to cytoplasm upon DNA replication stress. | RNA polymerase subunit AC19; common to RNA polymerases I and III. | 0.999 |
RPC10 | RPC25 | YHR143W-A | YKL144C | RNA polymerase subunit ABC10-alpha, found in RNA pol I, II, and III; relocalizes from nucleolus to cytoplasm upon DNA replication stress. | RNA polymerase III subunit C25; required for transcription initiation; forms a heterodimer with Rpc17p; paralog of Rpb7p. | 0.999 |
RPC10 | RPC31 | YHR143W-A | YNL151C | RNA polymerase subunit ABC10-alpha, found in RNA pol I, II, and III; relocalizes from nucleolus to cytoplasm upon DNA replication stress. | RNA polymerase III subunit C31; Belongs to the eukaryotic RPC7 RNA polymerase subunit family. | 0.996 |
RPC10 | RPC34 | YHR143W-A | YNR003C | RNA polymerase subunit ABC10-alpha, found in RNA pol I, II, and III; relocalizes from nucleolus to cytoplasm upon DNA replication stress. | RNA polymerase III subunit C34; interacts with TFIIIB70 and is a key determinant in pol III recruitment by the preinitiation complex; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. | 0.998 |
RPC10 | RPC37 | YHR143W-A | YKR025W | RNA polymerase subunit ABC10-alpha, found in RNA pol I, II, and III; relocalizes from nucleolus to cytoplasm upon DNA replication stress. | RNA polymerase III subunit C37. | 0.999 |
RPC10 | RPC53 | YHR143W-A | YDL150W | RNA polymerase subunit ABC10-alpha, found in RNA pol I, II, and III; relocalizes from nucleolus to cytoplasm upon DNA replication stress. | RNA polymerase III subunit C53; Belongs to the eukaryotic RPC4/POLR3D RNA polymerase subunit family. | 0.999 |
RPC10 | RPO31 | YHR143W-A | YOR116C | RNA polymerase subunit ABC10-alpha, found in RNA pol I, II, and III; relocalizes from nucleolus to cytoplasm upon DNA replication stress. | RNA polymerase III largest subunit C160; part of core enzyme; similar to bacterial beta-prime subunit and to RPA190 and RPO21; Belongs to the RNA polymerase beta' chain family. | 0.999 |