| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADP1 | CAF16 | YCR011C | YFL028C | Putative ATP-dependent permease of the ABC transporter family; Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily. | CCR4-associated factor 16; Part of evolutionarily-conserved CCR4-NOT regulatory complex; contains single ABC-type ATPase domain but no transmembrane domain; interacts with several subunits of Mediator; Belongs to the ABC transporter superfamily. | 0.646 |
| ADP1 | RLI1 | YCR011C | YDR091C | Putative ATP-dependent permease of the ABC transporter family; Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily. | Translation initiation factor RLI1; Essential Fe-S protein; required for ribosome biogenesis, translation initiation/termination; facilitates binding of multifactor complex (MFC) of initiation factors to small ribosomal subunit; Dom34-Hbs1 complex and Rli1p work in dissociating inactive ribosomes, thereby facilitating translation restart; forms complex with Lto1p and Yae1p; dependency on ROS-labile FeS clusters, activity in nuclear ribosomal-subunit export impaired by mild oxidative stress. | 0.568 |
| ADP1 | YDR061W | YCR011C | YDR061W | Putative ATP-dependent permease of the ABC transporter family; Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily. | Protein with similarity to ABC transporter family members; lacks predicted membrane-spanning regions; transcriptionally activated by Yrm1p along with genes involved in multidrug resistance. | 0.722 |
| CAF16 | ADP1 | YFL028C | YCR011C | CCR4-associated factor 16; Part of evolutionarily-conserved CCR4-NOT regulatory complex; contains single ABC-type ATPase domain but no transmembrane domain; interacts with several subunits of Mediator; Belongs to the ABC transporter superfamily. | Putative ATP-dependent permease of the ABC transporter family; Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily. | 0.646 |
| CAF16 | YDR061W | YFL028C | YDR061W | CCR4-associated factor 16; Part of evolutionarily-conserved CCR4-NOT regulatory complex; contains single ABC-type ATPase domain but no transmembrane domain; interacts with several subunits of Mediator; Belongs to the ABC transporter superfamily. | Protein with similarity to ABC transporter family members; lacks predicted membrane-spanning regions; transcriptionally activated by Yrm1p along with genes involved in multidrug resistance. | 0.900 |
| MRPL39 | PUF3 | YML009C | YLL013C | Mitochondrial ribosomal protein of the large subunit. | mRNA-binding protein PUF3; Protein of the mitochondrial outer surface; links the Arp2/3 complex with the mitochore during anterograde mitochondrial movement; also binds to and promotes degradation of mRNAs for select nuclear-encoded mitochondrial proteins. | 0.976 |
| MRPL39 | YDR061W | YML009C | YDR061W | Mitochondrial ribosomal protein of the large subunit. | Protein with similarity to ABC transporter family members; lacks predicted membrane-spanning regions; transcriptionally activated by Yrm1p along with genes involved in multidrug resistance. | 0.676 |
| PET112 | PUF3 | YBL080C | YLL013C | Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex; involved in the formation of Q-tRNAQ; mutation is functionally complemented by the bacterial GatB ortholog; Belongs to the GatB/GatE family. GatB subfamily. | mRNA-binding protein PUF3; Protein of the mitochondrial outer surface; links the Arp2/3 complex with the mitochore during anterograde mitochondrial movement; also binds to and promotes degradation of mRNAs for select nuclear-encoded mitochondrial proteins. | 0.457 |
| PET112 | YDR061W | YBL080C | YDR061W | Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex; involved in the formation of Q-tRNAQ; mutation is functionally complemented by the bacterial GatB ortholog; Belongs to the GatB/GatE family. GatB subfamily. | Protein with similarity to ABC transporter family members; lacks predicted membrane-spanning regions; transcriptionally activated by Yrm1p along with genes involved in multidrug resistance. | 0.741 |
| PUF3 | MRPL39 | YLL013C | YML009C | mRNA-binding protein PUF3; Protein of the mitochondrial outer surface; links the Arp2/3 complex with the mitochore during anterograde mitochondrial movement; also binds to and promotes degradation of mRNAs for select nuclear-encoded mitochondrial proteins. | Mitochondrial ribosomal protein of the large subunit. | 0.976 |
| PUF3 | PET112 | YLL013C | YBL080C | mRNA-binding protein PUF3; Protein of the mitochondrial outer surface; links the Arp2/3 complex with the mitochore during anterograde mitochondrial movement; also binds to and promotes degradation of mRNAs for select nuclear-encoded mitochondrial proteins. | Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex; involved in the formation of Q-tRNAQ; mutation is functionally complemented by the bacterial GatB ortholog; Belongs to the GatB/GatE family. GatB subfamily. | 0.457 |
| PUF3 | YDR061W | YLL013C | YDR061W | mRNA-binding protein PUF3; Protein of the mitochondrial outer surface; links the Arp2/3 complex with the mitochore during anterograde mitochondrial movement; also binds to and promotes degradation of mRNAs for select nuclear-encoded mitochondrial proteins. | Protein with similarity to ABC transporter family members; lacks predicted membrane-spanning regions; transcriptionally activated by Yrm1p along with genes involved in multidrug resistance. | 0.918 |
| RLI1 | ADP1 | YDR091C | YCR011C | Translation initiation factor RLI1; Essential Fe-S protein; required for ribosome biogenesis, translation initiation/termination; facilitates binding of multifactor complex (MFC) of initiation factors to small ribosomal subunit; Dom34-Hbs1 complex and Rli1p work in dissociating inactive ribosomes, thereby facilitating translation restart; forms complex with Lto1p and Yae1p; dependency on ROS-labile FeS clusters, activity in nuclear ribosomal-subunit export impaired by mild oxidative stress. | Putative ATP-dependent permease of the ABC transporter family; Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily. | 0.568 |
| RLI1 | YDR061W | YDR091C | YDR061W | Translation initiation factor RLI1; Essential Fe-S protein; required for ribosome biogenesis, translation initiation/termination; facilitates binding of multifactor complex (MFC) of initiation factors to small ribosomal subunit; Dom34-Hbs1 complex and Rli1p work in dissociating inactive ribosomes, thereby facilitating translation restart; forms complex with Lto1p and Yae1p; dependency on ROS-labile FeS clusters, activity in nuclear ribosomal-subunit export impaired by mild oxidative stress. | Protein with similarity to ABC transporter family members; lacks predicted membrane-spanning regions; transcriptionally activated by Yrm1p along with genes involved in multidrug resistance. | 0.844 |
| YBR053C | YDR061W | YBR053C | YDR061W | Uncharacterized protein YBR053C; Putative protein of unknown function; induced by cell wall perturbation. | Protein with similarity to ABC transporter family members; lacks predicted membrane-spanning regions; transcriptionally activated by Yrm1p along with genes involved in multidrug resistance. | 0.755 |
| YBR053C | YMR027W | YBR053C | YMR027W | Uncharacterized protein YBR053C; Putative protein of unknown function; induced by cell wall perturbation. | Damage-control phosphatase YMR027W; A metal-dependent phosphatase, part of the DUF89 protein family; dephosphorylates fructose-1-phosphate; human ortholog, C6orf211 is involved in response to DNA damage; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and cytoplasm; YMR027W is not an essential gene; Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily. | 0.765 |
| YBR053C | YMR090W | YBR053C | YMR090W | Uncharacterized protein YBR053C; Putative protein of unknown function; induced by cell wall perturbation. | UPF0659 protein YMR090W; Putative protein of unknown function; similar to DTDP-glucose 4,6-dehydratases; GFP-fusion protein localizes to the cytoplasm; up-regulated in response to the fungicide mancozeb; not essential for viability; Belongs to the UPF0659 family. | 0.742 |
| YBR053C | YOR289W | YBR053C | YOR289W | Uncharacterized protein YBR053C; Putative protein of unknown function; induced by cell wall perturbation. | Uncharacterized protein YOR289W; Putative protein of unknown function; transcription induced by the unfolded protein response; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus. | 0.799 |
| YDR061W | ADP1 | YDR061W | YCR011C | Protein with similarity to ABC transporter family members; lacks predicted membrane-spanning regions; transcriptionally activated by Yrm1p along with genes involved in multidrug resistance. | Putative ATP-dependent permease of the ABC transporter family; Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily. | 0.722 |
| YDR061W | CAF16 | YDR061W | YFL028C | Protein with similarity to ABC transporter family members; lacks predicted membrane-spanning regions; transcriptionally activated by Yrm1p along with genes involved in multidrug resistance. | CCR4-associated factor 16; Part of evolutionarily-conserved CCR4-NOT regulatory complex; contains single ABC-type ATPase domain but no transmembrane domain; interacts with several subunits of Mediator; Belongs to the ABC transporter superfamily. | 0.900 |
