node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DOS2 | KRE2 | YDR068W | YDR483W | Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm. | Glycolipid 2-alpha-mannosyltransferase; Alpha1,2-mannosyltransferase of the Golgi; involved in protein mannosylation; KRE2 has a paralog, KTR6, that arose from the whole genome duplication. | 0.624 |
DOS2 | OCA6 | YDR068W | YDR067C | Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm. | Putative tyrosine-protein phosphatase OCA6; Cytoplasmic protein required for replication of Brome mosaic virus; S. cerevisiae is a model system for studying positive-strand RNA virus replication; null mutation confers sensitivity to tunicamycin and DTT. | 0.667 |
DOS2 | ROX1 | YDR068W | YPR065W | Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm. | Heme-dependent repressor of hypoxic genes; mediates aerobic transcriptional repression of hypoxia induced genes such as COX5b and CYC7; repressor function regulated through decreased promoter occupancy in response to oxidative stress; contains an HMG domain that is responsible for DNA bending activity; involved in the hyperosmotic stress resistance. | 0.634 |
DOS2 | VBA5 | YDR068W | YKR105C | Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm. | Vacuolar basic amino acid transporter 5; Plasma membrane protein of the Major Facilitator Superfamily (MFS); involved in amino acid uptake and drug sensitivity; VBA5 has a paralog, VBA3, that arose from a segmental duplication. | 0.758 |
DOS2 | YER134C | YDR068W | YER134C | Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm. | Magnesium-dependent acid phosphatase; member of the haloacid dehalogenase superfamily; non-essential gene; Belongs to the HAD-like hydrolase superfamily. | 0.905 |
DOS2 | YGR259C | YDR068W | YGR259C | Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm. | Putative uncharacterized protein YGR259C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps almost completely with the verified ORF TNA1/YGR260W. | 0.909 |
DOS2 | YJL064W | YDR068W | YJL064W | Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm. | Putative uncharacterized protein YJL064W; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; completely overlaps the verified gene YJL065C/DLS1. | 0.793 |
DOS2 | YNR063W | YDR068W | YNR063W | Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm. | Uncharacterized transcriptional regulatory protein YNR063W; Putative zinc-cluster protein of unknown function. | 0.903 |
DOS2 | YOR292C | YDR068W | YOR292C | Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm. | Vacuolar membrane protein YOR292C; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; YOR292C is not an essential gene; Belongs to the peroxisomal membrane protein PXMP2/4 family. | 0.692 |
DOS2 | YPL062W | YDR068W | YPL062W | Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm. | Uncharacterized protein YPL062W; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; YPL062W is not an essential gene; homozygous diploid mutant shows a decrease in glycogen accumulation. | 0.699 |
KRE2 | DOS2 | YDR483W | YDR068W | Glycolipid 2-alpha-mannosyltransferase; Alpha1,2-mannosyltransferase of the Golgi; involved in protein mannosylation; KRE2 has a paralog, KTR6, that arose from the whole genome duplication. | Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm. | 0.624 |
OCA6 | DOS2 | YDR067C | YDR068W | Putative tyrosine-protein phosphatase OCA6; Cytoplasmic protein required for replication of Brome mosaic virus; S. cerevisiae is a model system for studying positive-strand RNA virus replication; null mutation confers sensitivity to tunicamycin and DTT. | Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm. | 0.667 |
ROX1 | DOS2 | YPR065W | YDR068W | Heme-dependent repressor of hypoxic genes; mediates aerobic transcriptional repression of hypoxia induced genes such as COX5b and CYC7; repressor function regulated through decreased promoter occupancy in response to oxidative stress; contains an HMG domain that is responsible for DNA bending activity; involved in the hyperosmotic stress resistance. | Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm. | 0.634 |
ROX1 | YER134C | YPR065W | YER134C | Heme-dependent repressor of hypoxic genes; mediates aerobic transcriptional repression of hypoxia induced genes such as COX5b and CYC7; repressor function regulated through decreased promoter occupancy in response to oxidative stress; contains an HMG domain that is responsible for DNA bending activity; involved in the hyperosmotic stress resistance. | Magnesium-dependent acid phosphatase; member of the haloacid dehalogenase superfamily; non-essential gene; Belongs to the HAD-like hydrolase superfamily. | 0.604 |
ROX1 | YGR259C | YPR065W | YGR259C | Heme-dependent repressor of hypoxic genes; mediates aerobic transcriptional repression of hypoxia induced genes such as COX5b and CYC7; repressor function regulated through decreased promoter occupancy in response to oxidative stress; contains an HMG domain that is responsible for DNA bending activity; involved in the hyperosmotic stress resistance. | Putative uncharacterized protein YGR259C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps almost completely with the verified ORF TNA1/YGR260W. | 0.630 |
ROX1 | YJL064W | YPR065W | YJL064W | Heme-dependent repressor of hypoxic genes; mediates aerobic transcriptional repression of hypoxia induced genes such as COX5b and CYC7; repressor function regulated through decreased promoter occupancy in response to oxidative stress; contains an HMG domain that is responsible for DNA bending activity; involved in the hyperosmotic stress resistance. | Putative uncharacterized protein YJL064W; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; completely overlaps the verified gene YJL065C/DLS1. | 0.831 |
ROX1 | YNR063W | YPR065W | YNR063W | Heme-dependent repressor of hypoxic genes; mediates aerobic transcriptional repression of hypoxia induced genes such as COX5b and CYC7; repressor function regulated through decreased promoter occupancy in response to oxidative stress; contains an HMG domain that is responsible for DNA bending activity; involved in the hyperosmotic stress resistance. | Uncharacterized transcriptional regulatory protein YNR063W; Putative zinc-cluster protein of unknown function. | 0.548 |
ROX1 | YPL062W | YPR065W | YPL062W | Heme-dependent repressor of hypoxic genes; mediates aerobic transcriptional repression of hypoxia induced genes such as COX5b and CYC7; repressor function regulated through decreased promoter occupancy in response to oxidative stress; contains an HMG domain that is responsible for DNA bending activity; involved in the hyperosmotic stress resistance. | Uncharacterized protein YPL062W; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; YPL062W is not an essential gene; homozygous diploid mutant shows a decrease in glycogen accumulation. | 0.792 |
VBA5 | DOS2 | YKR105C | YDR068W | Vacuolar basic amino acid transporter 5; Plasma membrane protein of the Major Facilitator Superfamily (MFS); involved in amino acid uptake and drug sensitivity; VBA5 has a paralog, VBA3, that arose from a segmental duplication. | Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm. | 0.758 |
VBA5 | YER134C | YKR105C | YER134C | Vacuolar basic amino acid transporter 5; Plasma membrane protein of the Major Facilitator Superfamily (MFS); involved in amino acid uptake and drug sensitivity; VBA5 has a paralog, VBA3, that arose from a segmental duplication. | Magnesium-dependent acid phosphatase; member of the haloacid dehalogenase superfamily; non-essential gene; Belongs to the HAD-like hydrolase superfamily. | 0.832 |