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DOS2 protein (Saccharomyces cerevisiae) - STRING interaction network
"DOS2" - Protein of unknown function, green fluorescent protein in Saccharomyces cerevisiae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
DOS2Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; Acts in ubiquitin metabolism and is necessary for the control of single-copy DNA replication (310 aa)    
Predicted Functional Partners:
AUR1
Phosphatidylinositol-ceramide phosphoinositol transferase (IPC synthase), required for sphingolipid synthesis; can mutate to confer aureobasidin A resistance; Catalytic component of the inositol phosphorylceramide synthase which catalyzes the addition of a phosphorylinositol group onto ceramide to form inositol phosphorylceramide, an essential step in sphingolipid biosynthesis (401 aa)
       
      0.868
YER134C
Magnesium-dependent acid phosphatase, member of the haloacid dehalogenase superfamily; non-essential gene; Magnesium-dependent phosphatase which may act as a tyrosine phosphatase (178 aa)
           
  0.760
YNR063W
Putative zinc-cluster protein of unknown function (607 aa)
           
  0.739
KRE2
Alpha1,2-mannosyltransferase of the Golgi involved in protein mannosylation; Required for the attachment of the third mannose residue of O-linked saccharides (442 aa)
       
      0.707
YGR259C
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps almost completely with the verified ORF TNA1/YGR260W (146 aa)
           
  0.698
EMC10
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YDR056C is not an essential protein (205 aa)
     
        0.599
SLU7
RNA splicing factor, required for ATP-independent portion of 2nd catalytic step of spliceosomal RNA splicing; interacts with Prp18p; contains zinc knuckle domain; Essential protein involved in the second catalytic step of pre-mRNA splicing. Involved in the selection of 3’-type splice sites; this selection could be done via a 3’-splice site-binding factor, PRP16 (382 aa)
     
   
  0.550
VMS1
Component of a Cdc48p-complex involved in protein quality control; exhibits cytosolic and ER-membrane localization, with Cdc48p, during normal growth, and contributes to ER-associated degradation (ERAD) of specific substrates at a step after their u /.../ination; forms a mitochondrially-associated complex with Cdc48p and Npl4p under oxidative stress that is required for ubiquitin-mediated mitochondria-associated protein degradation (MAD); conserved in C. elegans and humans; Involved in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway. Component of an evolutionarily [...] (632 aa)
     
        0.534
RTR2
Protein of unknown function with high similarity to Rtr1p; exhibits genetic interactions with Rtr1p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YDR066C is not an essential gene; Probable RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase that regulates RNA polymerase II transcription. May have functional redundancy with RTR1 (196 aa)
     
   
  0.503
YPL062W
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YPL062W is not an essential gene; homozygous diploid mutant shows a decrease in glycogen accumulation (134 aa)
           
  0.487
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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