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YDR089W protein (Saccharomyces cerevisiae) - STRING interaction network
"YDR089W" - Protein of unknown function in Saccharomyces cerevisiae
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
YDR089WProtein of unknown function; deletion confers resistance to Nickel (869 aa)    
Predicted Functional Partners:
YJR030C
Putative protein of unknown function; expression repressed in carbon limited vs carbon replete chemostat cultures; YJR030C is a non-essential gene (745 aa)
           
  0.540
YDR124W
Putative protein of unknown function; non-essential gene; expression is strongly induced by alpha factor (324 aa)
           
  0.540
MHF2
Putative protein of unknown function; mutant in a srs2 mutant background displays MMS hypersensitivity; ortholog of human MHF2, a component of the Fanconi anemia (FA) complex that is involved in maintaining genome stability; DNA-binding component of a FANCM-MHF complex involved in DNA damage repair and genome maintenance (PubMed-20347428). FANCM- MHF promotes gene conversion at blocked replication forks (By similarity) (80 aa)
           
  0.516
YCL049C
Protein of unknown function; localizes to membrane fraction; YCL049C is not an essential gene (312 aa)
           
  0.513
CAF120
Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex involved in controlling mRNA initiation, elongation, and degradation; Acts as component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes. Preferentially affects TC- type TATA element-dependent transcription. Could directly or indirectly inhibit component(s) of the general transcription machinery (1060 aa)
           
  0.485
SPO71
Meiosis-specific protein of unknown function, required for spore wall formation during sporulation; dispensable for both nuclear divisions during meiosis; Required for spore wall formation during sporulation (1245 aa)
           
  0.482
SKG3
Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck; potential Cdc28p substrate; similar to Caf120p and Skg4p; May play a role in cell wall integrity (1026 aa)
           
  0.481
YJL181W
Putative protein of unknown function; expression is cell-cycle regulated as shown by microarray analysis; potential regulatory target of Mbp1p, which binds to the YJL181W promoter region (611 aa)
           
  0.481
TFB5
Component of the RNA polymerase II general transcription and DNA repair factor TFIIH; involved in transcription initiation and in nucleotide-excision repair; homolog of Chlamydomonas reinhardtii REX1-S protein involved in DNA repair; Acts as component of the general transcription and DNA repair factor IIH (TFIIH) core, which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA. TFIIH has CTD kinase and DNA-dependent ATPase activity, and is essential for polymerase II transcription in vitro. TFB5 is required for stab [...] (72 aa)
           
  0.468
LDB17
Protein involved in the regulation of endocytosis; transiently recruited to actin cortical patches in a SLA1-dependent manner after late coat component assembly; GFP-fusion protein localizes to the periphery, cytoplasm, bud, and bud neck; May be involved in protein-linked oligosaccharide phosphorylation since the deletion reduces the negative charge of the cell surface (491 aa)
           
  0.448
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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