node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATG13 | ATG31 | YPR185W | YDR022C | Autophagy-related protein 13; Regulatory subunit of the Atg1p signaling complex; stimulates Atg1p kinase activity; required for vesicle formation during autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; contains a HORMA domain required for autophagy and for recruitment of the phosphatidylinositol 3-kinase complex subunit Atg14p to the pre-autophagosomal structure; Belongs to the ATG13 family. Fungi subfamily. | Autophagy-related protein 31; Autophagy-specific protein required for autophagosome formation; forms a complex with Atg17p and Atg29p that localizes other proteins to the pre-autophagosomal structure; constitutively phosphorylated, and phosphorylation of residue S174 is required for function; high-copy suppressor of CIK1 deletion. | 0.999 |
ATG13 | TVP15 | YPR185W | YDR100W | Autophagy-related protein 13; Regulatory subunit of the Atg1p signaling complex; stimulates Atg1p kinase activity; required for vesicle formation during autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; contains a HORMA domain required for autophagy and for recruitment of the phosphatidylinositol 3-kinase complex subunit Atg14p to the pre-autophagosomal structure; Belongs to the ATG13 family. Fungi subfamily. | Integral membrane protein; localized to late Golgi vesicles along with the v-SNARE Tlg2p. | 0.639 |
ATG13 | TVP23 | YPR185W | YDR084C | Autophagy-related protein 13; Regulatory subunit of the Atg1p signaling complex; stimulates Atg1p kinase activity; required for vesicle formation during autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; contains a HORMA domain required for autophagy and for recruitment of the phosphatidylinositol 3-kinase complex subunit Atg14p to the pre-autophagosomal structure; Belongs to the ATG13 family. Fungi subfamily. | Integral membrane protein; localized to late Golgi vesicles along with the v-SNARE Tlg2p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; Belongs to the TVP23 family. | 0.474 |
ATG31 | ATG13 | YDR022C | YPR185W | Autophagy-related protein 31; Autophagy-specific protein required for autophagosome formation; forms a complex with Atg17p and Atg29p that localizes other proteins to the pre-autophagosomal structure; constitutively phosphorylated, and phosphorylation of residue S174 is required for function; high-copy suppressor of CIK1 deletion. | Autophagy-related protein 13; Regulatory subunit of the Atg1p signaling complex; stimulates Atg1p kinase activity; required for vesicle formation during autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; contains a HORMA domain required for autophagy and for recruitment of the phosphatidylinositol 3-kinase complex subunit Atg14p to the pre-autophagosomal structure; Belongs to the ATG13 family. Fungi subfamily. | 0.999 |
ATG31 | TVP15 | YDR022C | YDR100W | Autophagy-related protein 31; Autophagy-specific protein required for autophagosome formation; forms a complex with Atg17p and Atg29p that localizes other proteins to the pre-autophagosomal structure; constitutively phosphorylated, and phosphorylation of residue S174 is required for function; high-copy suppressor of CIK1 deletion. | Integral membrane protein; localized to late Golgi vesicles along with the v-SNARE Tlg2p. | 0.671 |
GVP36 | TVP15 | YIL041W | YDR100W | BAR domain protein that localizes to early and late Golgi vesicles; required for adaptation to varying nutrient concentrations, fluid-phase endocytosis, polarization of the actin cytoskeleton, and vacuole biogenesis. | Integral membrane protein; localized to late Golgi vesicles along with the v-SNARE Tlg2p. | 0.706 |
GVP36 | TVP18 | YIL041W | YMR071C | BAR domain protein that localizes to early and late Golgi vesicles; required for adaptation to varying nutrient concentrations, fluid-phase endocytosis, polarization of the actin cytoskeleton, and vacuole biogenesis. | Integral membrane protein; localized to late Golgi vesicles along with the v-SNARE Tlg2p; may interact with ribosomes, based on co-purification experiments; may have a role in intracellular sterol transport. | 0.604 |
GVP36 | TVP23 | YIL041W | YDR084C | BAR domain protein that localizes to early and late Golgi vesicles; required for adaptation to varying nutrient concentrations, fluid-phase endocytosis, polarization of the actin cytoskeleton, and vacuole biogenesis. | Integral membrane protein; localized to late Golgi vesicles along with the v-SNARE Tlg2p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; Belongs to the TVP23 family. | 0.597 |
GVP36 | TVP38 | YIL041W | YKR088C | BAR domain protein that localizes to early and late Golgi vesicles; required for adaptation to varying nutrient concentrations, fluid-phase endocytosis, polarization of the actin cytoskeleton, and vacuole biogenesis. | Integral membrane protein; localized to late Golgi vesicles along with the v-SNARE Tlg2p; required for asymmetric localization of Kar9p during mitosis; GFP-fusion protein localizes to the cytoplasm in a punctate pattern. | 0.703 |
SVP26 | SYS1 | YHR181W | YJL004C | Integral membrane protein of the early Golgi apparatus and ER; involved in COP II vesicle transport; may also function to promote retention of proteins in the early Golgi compartment. | Protein SYS1; Integral membrane protein of the Golgi; required for targeting of the Arf-like GTPase Arl3p to the Golgi; multicopy suppressor of ypt6 null mutation. | 0.464 |
SVP26 | TVP15 | YHR181W | YDR100W | Integral membrane protein of the early Golgi apparatus and ER; involved in COP II vesicle transport; may also function to promote retention of proteins in the early Golgi compartment. | Integral membrane protein; localized to late Golgi vesicles along with the v-SNARE Tlg2p. | 0.646 |
SVP26 | TVP18 | YHR181W | YMR071C | Integral membrane protein of the early Golgi apparatus and ER; involved in COP II vesicle transport; may also function to promote retention of proteins in the early Golgi compartment. | Integral membrane protein; localized to late Golgi vesicles along with the v-SNARE Tlg2p; may interact with ribosomes, based on co-purification experiments; may have a role in intracellular sterol transport. | 0.583 |
SVP26 | TVP23 | YHR181W | YDR084C | Integral membrane protein of the early Golgi apparatus and ER; involved in COP II vesicle transport; may also function to promote retention of proteins in the early Golgi compartment. | Integral membrane protein; localized to late Golgi vesicles along with the v-SNARE Tlg2p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; Belongs to the TVP23 family. | 0.801 |
SVP26 | TVP38 | YHR181W | YKR088C | Integral membrane protein of the early Golgi apparatus and ER; involved in COP II vesicle transport; may also function to promote retention of proteins in the early Golgi compartment. | Integral membrane protein; localized to late Golgi vesicles along with the v-SNARE Tlg2p; required for asymmetric localization of Kar9p during mitosis; GFP-fusion protein localizes to the cytoplasm in a punctate pattern. | 0.457 |
SYS1 | SVP26 | YJL004C | YHR181W | Protein SYS1; Integral membrane protein of the Golgi; required for targeting of the Arf-like GTPase Arl3p to the Golgi; multicopy suppressor of ypt6 null mutation. | Integral membrane protein of the early Golgi apparatus and ER; involved in COP II vesicle transport; may also function to promote retention of proteins in the early Golgi compartment. | 0.464 |
SYS1 | TVP15 | YJL004C | YDR100W | Protein SYS1; Integral membrane protein of the Golgi; required for targeting of the Arf-like GTPase Arl3p to the Golgi; multicopy suppressor of ypt6 null mutation. | Integral membrane protein; localized to late Golgi vesicles along with the v-SNARE Tlg2p. | 0.636 |
TVP15 | ATG13 | YDR100W | YPR185W | Integral membrane protein; localized to late Golgi vesicles along with the v-SNARE Tlg2p. | Autophagy-related protein 13; Regulatory subunit of the Atg1p signaling complex; stimulates Atg1p kinase activity; required for vesicle formation during autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; contains a HORMA domain required for autophagy and for recruitment of the phosphatidylinositol 3-kinase complex subunit Atg14p to the pre-autophagosomal structure; Belongs to the ATG13 family. Fungi subfamily. | 0.639 |
TVP15 | ATG31 | YDR100W | YDR022C | Integral membrane protein; localized to late Golgi vesicles along with the v-SNARE Tlg2p. | Autophagy-related protein 31; Autophagy-specific protein required for autophagosome formation; forms a complex with Atg17p and Atg29p that localizes other proteins to the pre-autophagosomal structure; constitutively phosphorylated, and phosphorylation of residue S174 is required for function; high-copy suppressor of CIK1 deletion. | 0.671 |
TVP15 | GVP36 | YDR100W | YIL041W | Integral membrane protein; localized to late Golgi vesicles along with the v-SNARE Tlg2p. | BAR domain protein that localizes to early and late Golgi vesicles; required for adaptation to varying nutrient concentrations, fluid-phase endocytosis, polarization of the actin cytoskeleton, and vacuole biogenesis. | 0.706 |
TVP15 | SVP26 | YDR100W | YHR181W | Integral membrane protein; localized to late Golgi vesicles along with the v-SNARE Tlg2p. | Integral membrane protein of the early Golgi apparatus and ER; involved in COP II vesicle transport; may also function to promote retention of proteins in the early Golgi compartment. | 0.646 |