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ARP10 protein (Saccharomyces cerevisiae) - STRING interaction network
"ARP10" - Component of the dynactin complex, localized to the pointed end of the Arp1p filament in Saccharomyces cerevisiae
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Known Interactions
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Predicted Interactions
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protein homology
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ARP10Component of the dynactin complex, localized to the pointed end of the Arp1p filament; may regulate membrane association of the complex; Pointed-end-associated component of the dynactin complex which assists cytoplasmic dynein by increasing its processivity and by regulation of its cargo binding (By similarity). The dynactin complex is required for the spindle translocation late in anaphase and is involved in a cell wall synthesis checkpoint. May regulate the association of the dynactin complex with the plasma membrane (284 aa)    
Predicted Functional Partners:
NIP100
Large subunit of the dynactin complex, which is involved in partitioning the mitotic spindle between mother and daughter cells; putative ortholog of mammalian p150(glued); Motor-binding component of the dynactin complex which assists cytoplasmic dynein by increasing its processivity and by regulation of its cargo binding (By similarity). The dynactin complex is required for the spindle translocation late in anaphase and is involved in a cell wall synthesis checkpoint (868 aa)
       
  0.962
ARP1
Actin-related protein of the dynactin complex; required for spindle orientation and nuclear migration; putative ortholog of mammalian centractin; Core component of the dynactin complex which assists cytoplasmic dynein by increasing its processivity and by regulation of its cargo binding (By similarity). The dynactin complex is required for the spindle translocation late in anaphase and is involved in a cell wall synthesis checkpoint. ARP1 forms the backbone filament of the dynactin rod structure and serves as the scaffold for the remaining subunits. Required for proper orientation of t [...] (384 aa)
       
  0.950
JNM1
Component of the yeast dynactin complex, consisting of Nip100p, Jnm1p, and Arp1p; required for proper nuclear migration and spindle partitioning during mitotic anaphase B; Component of the dynactin complex which assists cytoplasmic dynein by increasing its processivity and by regulation of its cargo binding (By similarity). The dynactin complex is required for the spindle translocation late in anaphase and is involved in a cell wall synthesis checkpoint. JNM1 is associated with the rod and links it to the projecting sidearm. Required for proper nuclear migration during the mitotic cell [...] (373 aa)
       
  0.941
LDB18
Component of the dynactin complex, which is required for dynein activity; null mutant exhibits defects in nuclear migration and spindle orientation and has reduced affinity for alcian blue dye; has homology to mammalian dynactin subunit p24; May be involved in protein-linked oligosaccharide phosphorylation since the deletion reduces the negative charge of the cell surface (179 aa)
       
  0.871
DYN1
Cytoplasmic heavy chain dynein, microtubule motor protein, required for anaphase spindle elongation; involved in spindle assembly, chromosome movement, and spindle orientation during cell division, targeted to microtubule tips by Pac1p; Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required to maintain uniform nuclear distribution in hyphae. May play an important role in the proper orientation of the mitotic sp [...] (4092 aa)
         
  0.658
YBR226C
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YBR225W (136 aa)
           
  0.642
BSC2
Protein of unknown function, ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression (235 aa)
           
  0.578
YBL081W
Non-essential protein of unknown function; null mutation results in a decrease in plasma membrane electron transport (368 aa)
           
  0.544
NRP1
Putative RNA binding protein of unknown function; localizes to stress granules induced by glucose deprivation; predicted to be involved in ribosome biogenesis (719 aa)
           
  0.487
IRC20
Putative helicase; localizes to the mitochondrion and the nucleus; YLR247C is not an essential gene; null mutant displays increased levels of spontaneous Rad52p foci; Is probably involved in a pathway contributing to genomic integrity (1556 aa)
           
  0.469
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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