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MHR1 protein (Saccharomyces cerevisiae) - STRING interaction network
"MHR1" - Protein involved in homologous recombination in mitochondria in Saccharomyces cerevisiae
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
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MHR1Protein involved in homologous recombination in mitochondria; required for recombination-dependent mtDNA partitioning; involved in stimulation of mitochondrial DNA replication in response to oxidative stress; Transcription factor involved in regulation of RNA polymerase II-dependent transcription. Also involved in regulation of mitochondrial DNA recombination, maintenance and repair, and generation of homoplasmic cells (226 aa)    
Predicted Functional Partners:
CCE1
Mitochondrial cruciform cutting endonuclease, cleaves Holliday junctions formed during recombination of mitochondrial DNA; Capable of resolving Holliday junctions. Specific for 4- way junctions. Seems to be important for the maintenance of mitochondrial DNA. Cleaves fixed junctions at the point of strand exchange. Cleaves after 5’-CT-3’ sequence (353 aa)
       
 
  0.927
MRPL8
Mitochondrial ribosomal protein of the large subunit (238 aa)
     
      0.926
MRPL16
Mitochondrial ribosomal protein of the large subunit (232 aa)
     
      0.923
MRPL9
Mitochondrial ribosomal protein of the large subunit (269 aa)
     
 
  0.921
MRPL35
Mitochondrial ribosomal protein of the large subunit (367 aa)
     
      0.914
MRPL24
Mitochondrial ribosomal protein of the large subunit; two mitochondrial ribosomal proteins, YmL14 and YmL24, have been assigned to the same gene (258 aa)
     
      0.907
IMG1
Mitochondrial ribosomal protein of the large subunit, required for respiration and for maintenance of the mitochondrial genome; Essential for respiration (169 aa)
     
      0.906
MRPL28
Mitochondrial ribosomal protein of the large subunit (147 aa)
     
      0.905
MRP20
Mitochondrial ribosomal protein of the large subunit (263 aa)
     
      0.904
MRPL4
Mitochondrial ribosomal protein of the large subunit, homolog of prokaryotic L29 ribosomal protein; located at the ribosomal tunnel exit (319 aa)
     
      0.902
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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