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MRX8 protein (Saccharomyces cerevisiae) - STRING interaction network
"MRX8" - Putative protein of unknown function in Saccharomyces cerevisiae
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
MRX8Putative protein of unknown function; sumoylated under stress conditions in a genome wide study; YDR336W is not an essential gene; Component of MIOREX complexes, large expressome-like assemblies of ribosomes with factors involved in all the steps of post-transcriptional gene expression (314 aa)    
Predicted Functional Partners:
YGR021W
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies (290 aa)
   
   
  0.718
MRPS28
Mitochondrial ribosomal protein of the small subunit (286 aa)
   
   
  0.716
YOR111W
Putative protein of unknown function (232 aa)
       
 
  0.712
RMD8
Cytosolic protein required for sporulation; Required for sporulation (662 aa)
           
  0.697
RMD1
Cytoplasmic protein required for sporulation; Required for sporulation where it is believed to have a role in meiotic nuclear division (430 aa)
           
  0.697
YIH1
Protein that inhibits activation of Gcn2p, an eIF2 alpha subunit protein kinase, by competing for Gcn1p binding, thus impacting gene expression in response to starvation; has sequence and functional similarity to the mouse IMPACT gene; Translational regulator that ensures constant high levels of translation under amino acid starvation. Plays a role as a negative regulator of the GCN2 kinase activity; impairs GCN1- mediated GCN2 activation, and hence GCN2-mediated eIF-2-alpha phosphorylation in amino acid-starved cells and subsequent down- regulation of protein synthesis (PubMed-1512650 [...] (258 aa)
           
  0.697
CAB5
Probable dephospho-CoA kinase (DPCK) that catalyzes the last step in coenzyme A biosynthesis; null mutant lethality is complemented by E. coli coaE (encoding DPCK); detected in purified mitochondria in high-throughput studies; Catalyzes the phosphorylation of the 3’-hydroxyl group of dephosphocoenzyme A to form coenzyme A (241 aa)
         
  0.680
YFR006W
Putative X-Pro aminopeptidase; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YFR006W is not an essential gene (535 aa)
         
  0.642
YIR042C
Putative protein of unknown function; YIR042C is a non-essential gene (236 aa)
         
  0.641
YNR029C
Putative protein of unknown function, deletion confers reduced fitness in saline (429 aa)
   
   
  0.639
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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