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YPS7 protein (Saccharomyces cerevisiae) - STRING interaction network
"YPS7" - Putative GPI-anchored aspartic protease, member of the yapsin family of proteases involved in cell wall growth and maintenance in Saccharomyces cerevisiae
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Known Interactions
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Predicted Interactions
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gene co-occurrence
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textmining
co-expression
protein homology
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YPS7Putative GPI-anchored aspartic protease, member of the yapsin family of proteases involved in cell wall growth and maintenance; located in the cytoplasm and endoplasmic reticulum (596 aa)    
Predicted Functional Partners:
SSE2
Member of the heat shock protein 70 (HSP70) family; may be involved in protein folding; localized to the cytoplasm; highly homologous to the heat shock protein Sse1p; Has a calcium-dependent calmodulin-binding activity (693 aa)
       
 
  0.851
KEX2
Subtilisin-like protease (proprotein convertase), a calcium-dependent serine protease involved in the activation of proproteins of the secretory pathway; Processing of precursors of alpha-factors and killer toxin (814 aa)
     
 
  0.832
SEN1
Presumed helicase required for RNA polymerase II transcription termination and processing of RNAs; homolog of Senataxin which causes Ataxia-Oculomotor Apraxia 2 and a dominant form of amyotrophic lateral sclerosis; ATP-dependent 5’->3’ DNA/RNA helicase required for the expression and maturation of diverse classes of non-protein-coding RNAs like precursor tRNAs, rRNAs and small nuclear (snRNA) and nucleolar (snoRNA) RNAs. Directs RNA polymerase II transcription termination on snoRNAs as well as on several short protein-coding genes. May also play a role in transcription-coupled nucleoti [...] (2231 aa)
     
      0.803
YPS1
Aspartic protease, member of the yapsin family of proteases involved in cell wall growth and maintenance; attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor; Cleaves proteins C-terminally to mono- and paired-basic residues. Involved in the shedding of a subset of GPI-anchored plasma membrane proteins from the cell surface, including itself, GAS1 and MSB2. May also play a role in the maturation of GPI- mannoproteins associated with the cell wall. Can process the alpha-mating factor precursor. Required for cell wall integrity (569 aa)
       
 
0.742
MKC7
GPI-anchored aspartyl protease, member of the yapsin family of proteases involved in cell wall growth and maintenance; shares functions with Yap3p and Kex2p; Cleaves proteins C-terminally to the most C-terminal basic residue. Can process the alpha-mating factor precursor. Required for cell wall integrity (596 aa)
       
 
0.741
YPS6
Putative GPI-anchored aspartic protease, member of the yapsin family of proteases involved in cell wall growth and maintenance; Cleaves proteins C-terminally to mono- and paired-basic residues (By similarity). Required for cell wall integrity (537 aa)
       
 
0.730
RBL2
Protein involved in microtubule morphogenesis, required for protection from excess free beta-tubulin; proposed to be involved the folding of beta-tubulin; similar to mouse beta-tubulin cofactor A; Tubulin-folding protein; involved in the early step of the tubulin folding pathway (106 aa)
       
      0.687
PMT6
Protein O-mannosyltransferase, transfers mannose from dolichyl phosphate-D-mannose to protein serine/threonine residues of secretory proteins; reaction is essential for cell wall rigidity; member of a family of mannosyltransferases; Protein O-mannosyltransferase involved in O- glycosylation which is essential for cell wall rigidity. Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins (759 aa)
       
      0.673
PMT7
Putative protein of unknown function; Probable protein O-mannosyltransferase involved in O- glycosylation which is essential for cell wall rigidity. Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins (662 aa)
       
      0.673
LSC2
Beta subunit of succinyl-CoA ligase, which is a mitochondrial enzyme of the TCA cycle that catalyzes the nucleotide-dependent conversion of succinyl-CoA to succinate (427 aa)
       
      0.592
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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