STRINGSTRING
YDR396W protein (Saccharomyces cerevisiae) - STRING interaction network
"YDR396W" - Dubious open reading frame unlikely to encode a functional protein in Saccharomyces cerevisiae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YDR396WDubious open reading frame unlikely to encode a functional protein; extensively overlaps essential NCB2 gene encoding the beta subunit of the NC2 dimeric histone-fold complex (166 aa)    
Predicted Functional Partners:
YOL099C
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified gene PKH2/YOL100W; may interact with ribosomes (163 aa)
           
  0.738
YGR011W
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data (108 aa)
           
  0.738
YDL114W-A
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; identified based on homology to hemiascomycetous yeasts (37 aa)
           
  0.738
YDL240C-A
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; identified by sequence comparison with hemiascomycetous yeast species (45 aa)
           
  0.721
AIM26
Protein of unknown function; null mutant is viable and displays elevated frequency of mitochondrial genome loss; null mutation confers sensitivity to tunicamycin and DTT; Involved in selective mitochondria autophagy (mitophagy) (118 aa)
       
      0.677
YNR005C
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data (134 aa)
           
  0.626
NCB2
Subunit of a heterodimeric NC2 transcription regulator complex with Bur6p; complex binds to TBP and can repress transcription by preventing preinitiation complex assembly or stimulate activated transcription; homologous to human NC2beta; Component of the NC2 complex which represses RNA polymerase II transcription through binding to SPT15/TBP and thereby inhibiting the assembly of the preinitiation complex. The NC2 complex may also mediate transcriptional activation from TATA- driven promoters through association with SPT15/TBP (146 aa)
     
   
  0.604
YJL032W
Dubious open reading frame unlikely to encode a functional protein; overlaps 3’ end of essential BET4 gene encoding the alpha subunit of Type II geranylgeranyltransferase (104 aa)
     
   
  0.579
YLR198C
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene SIK1/YLR197W (119 aa)
     
   
  0.572
YOR105W
Protein of unknown function; expressed at both mRNA and protein levels (108 aa)
           
  0.542
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
Server load: low (6%) [HD]