STRINGSTRING
YDR445C protein (Saccharomyces cerevisiae) - STRING interaction network
"YDR445C" - Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data in Saccharomyces cerevisiae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YDR445CDubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data (135 aa)    
Predicted Functional Partners:
YDR444W
Putative protein of unknown function (687 aa)
           
  0.828
YJL007C
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data (104 aa)
           
  0.697
YPL216W
Putative protein of unknown function; YPL216W is not an essential gene; May be required for the activity of an ISWI chromatin- remodeling complex (1102 aa)
           
  0.624
RRT8
Putative protein of unknown function; identified in a screen for mutants with increased levels of rDNA transcription; green fluorescent protein (GFP)-fusion protein localizes to lipid particles; Involved in spore wall assembly (PubMed-23966878). May be involved in the modulation of rDNA transcription (PubMed-19270272) (342 aa)
           
  0.579
LDS2
Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; Involved in spore wall assembly (356 aa)
           
  0.579
HVG1
Protein of unknown function, has homology to Vrg4p; Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen (249 aa)
           
  0.575
CBP3
Mitochondrial protein required for assembly of cytochrome bc1 complex; forms a complex with Cbp6p that binds to mt ribosomes near the polypeptide tunnel exit and promotes efficient translation of the COB mRNA; Cbp3p-Cbp6p complex also interacts with /.../ synthesized cytochrome b (Cobp) and Cbp4p to promote assembly of Cobp into the cytochrome bc1 complex; Chaperone required for the assembly of ubiquinol- cytochrome c reductase of the mitochondrial respiratory chain (335 aa)
           
  0.489
ESF2
Essential nucleolar protein involved in pre-18S rRNA processing; binds to RNA and stimulates ATPase activity of Dbp8; involved in assembly of the small subunit (SSU) processome; Involved in the small subunit (SSU) processome assembly and function, and in the 18S rRNA synthesis. Required for the early cleavages at sites A0, A1 and A2. Stimulates DBP8 RNA helicase ATPase activity (316 aa)
           
  0.446
RRN11
Component of the core factor (CF) rDNA transcription factor complex; CF is required for transcription of 35S rRNA genes by RNA polymerase I and is composed of Rrn6p, Rrn7p, and Rrn11p; Acts as component of the core factor (CF) complex which is essential for the initiation of rDNA transcription by RNA polymerase I. After binding of UAF (upstream activation factor) to an upstream element of the promoter, CF is recruited in a SPT15/TBP-dependent manner to form a preinitiation complex (507 aa)
           
  0.440
LEA1
Component of U2 snRNP; disruption causes reduced U2 snRNP levels; physically interacts with Msl1p; putative homolog of human U2A’ snRNP protein; Involved in pre-mRNA splicing. Associates to U2 snRNA in a MSL1 dependent manner and is required for normal accumulation of U2 snRNA. Required for the spliceosome assembly and the efficient addition of U2 snRNP onto the pre-mRNA (238 aa)
           
  0.418
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
Server load: low (13%) [HD]