node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GLC7 | JIP4 | YER133W | YDR475C | Serine/threonine-protein phosphatase PP1-2; Type 1 S/T protein phosphatase (PP1) catalytic subunit; involved in glycogen metabolism, sporulation and mitotic progression; interacts with multiple regulatory subunits; regulates actomyosin ring formation; subunit of CPF; recruited to mating projections by Afr1p interaction; regulates nucleocytoplasmic shuttling of Hxk2p; import into the nucleus is inhibited during spindle assembly checkpoint arrest; involved in dephosphorylating Rps6a/b and Bnr1p. | Uncharacterized protein JIP4; Protein of unknown function; previously annotated as two separate ORFs, YDR474C and YDR475C, which were merged as a result of corrections to the systematic reference sequence; JIP4 has a paralog, YOR019W, that arose from the whole genome duplication. | 0.794 |
JIP3 | JIP4 | YLR331C | YDR475C | Uncharacterized protein JIP3; Putative protein of unknown function; conserved among S. cerevisiae strains; not conserved in closely related Saccharomyces species; 98% of ORF overlaps the verified gene MID2. | Uncharacterized protein JIP4; Protein of unknown function; previously annotated as two separate ORFs, YDR474C and YDR475C, which were merged as a result of corrections to the systematic reference sequence; JIP4 has a paralog, YOR019W, that arose from the whole genome duplication. | 0.760 |
JIP4 | GLC7 | YDR475C | YER133W | Uncharacterized protein JIP4; Protein of unknown function; previously annotated as two separate ORFs, YDR474C and YDR475C, which were merged as a result of corrections to the systematic reference sequence; JIP4 has a paralog, YOR019W, that arose from the whole genome duplication. | Serine/threonine-protein phosphatase PP1-2; Type 1 S/T protein phosphatase (PP1) catalytic subunit; involved in glycogen metabolism, sporulation and mitotic progression; interacts with multiple regulatory subunits; regulates actomyosin ring formation; subunit of CPF; recruited to mating projections by Afr1p interaction; regulates nucleocytoplasmic shuttling of Hxk2p; import into the nucleus is inhibited during spindle assembly checkpoint arrest; involved in dephosphorylating Rps6a/b and Bnr1p. | 0.794 |
JIP4 | JIP3 | YDR475C | YLR331C | Uncharacterized protein JIP4; Protein of unknown function; previously annotated as two separate ORFs, YDR474C and YDR475C, which were merged as a result of corrections to the systematic reference sequence; JIP4 has a paralog, YOR019W, that arose from the whole genome duplication. | Uncharacterized protein JIP3; Putative protein of unknown function; conserved among S. cerevisiae strains; not conserved in closely related Saccharomyces species; 98% of ORF overlaps the verified gene MID2. | 0.760 |
JIP4 | SNM1 | YDR475C | YDR478W | Uncharacterized protein JIP4; Protein of unknown function; previously annotated as two separate ORFs, YDR474C and YDR475C, which were merged as a result of corrections to the systematic reference sequence; JIP4 has a paralog, YOR019W, that arose from the whole genome duplication. | Ribonuclease MRP complex subunit; ribonuclease (RNase) MRP cleaves pre-rRNA and has a role in cell cycle-regulated degradation of daughter cell-specific mRNAs; binds to the NME1 RNA subunit of RNase MRP. | 0.758 |
JIP4 | TPH3 | YDR475C | YJL016W | Uncharacterized protein JIP4; Protein of unknown function; previously annotated as two separate ORFs, YDR474C and YDR475C, which were merged as a result of corrections to the systematic reference sequence; JIP4 has a paralog, YOR019W, that arose from the whole genome duplication. | Uncharacterized protein YJL016W; Putative protein of unknown function; GFP-fusion protein localizes to the cytoplasm; contains two adjacent PH-like domains; conserved in closely related Saccharomyces species. | 0.803 |
JIP4 | YDR476C | YDR475C | YDR476C | Uncharacterized protein JIP4; Protein of unknown function; previously annotated as two separate ORFs, YDR474C and YDR475C, which were merged as a result of corrections to the systematic reference sequence; JIP4 has a paralog, YOR019W, that arose from the whole genome duplication. | Uncharacterized protein YDR476C; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YDR476C is not an essential gene. | 0.697 |
JIP4 | YER084W | YDR475C | YER084W | Uncharacterized protein JIP4; Protein of unknown function; previously annotated as two separate ORFs, YDR474C and YDR475C, which were merged as a result of corrections to the systematic reference sequence; JIP4 has a paralog, YOR019W, that arose from the whole genome duplication. | Uncharacterized protein YER084W; Protein of unknown function; expressed at both mRNA and protein levels. | 0.693 |
JIP4 | YHR173C | YDR475C | YHR173C | Uncharacterized protein JIP4; Protein of unknown function; previously annotated as two separate ORFs, YDR474C and YDR475C, which were merged as a result of corrections to the systematic reference sequence; JIP4 has a paralog, YOR019W, that arose from the whole genome duplication. | Uncharacterized protein YHR173C; Protein of unknown function; expressed at both mRNA and protein levels; SWAT-GFP and mCherry fusion proteins localize to the vacuole. | 0.699 |
JIP4 | YNL140C | YDR475C | YNL140C | Uncharacterized protein JIP4; Protein of unknown function; previously annotated as two separate ORFs, YDR474C and YDR475C, which were merged as a result of corrections to the systematic reference sequence; JIP4 has a paralog, YOR019W, that arose from the whole genome duplication. | Uncharacterized protein YNL140C; Protein of unknown function; expressed at both mRNA and protein levels; partially overlaps THO2/YNL139C. | 0.697 |
JIP4 | YOR105W | YDR475C | YOR105W | Uncharacterized protein JIP4; Protein of unknown function; previously annotated as two separate ORFs, YDR474C and YDR475C, which were merged as a result of corrections to the systematic reference sequence; JIP4 has a paralog, YOR019W, that arose from the whole genome duplication. | Uncharacterized protein YOR105W; Protein of unknown function; expressed at both mRNA and protein levels. | 0.695 |
JIP4 | YPR089W | YDR475C | YPR089W | Uncharacterized protein JIP4; Protein of unknown function; previously annotated as two separate ORFs, YDR474C and YDR475C, which were merged as a result of corrections to the systematic reference sequence; JIP4 has a paralog, YOR019W, that arose from the whole genome duplication. | Dilute domain-containing protein YPR089W; Protein of unknown function; exhibits genetic interaction with ERG11 and protein-protein interaction with Hsp82p. | 0.816 |
SNM1 | JIP4 | YDR478W | YDR475C | Ribonuclease MRP complex subunit; ribonuclease (RNase) MRP cleaves pre-rRNA and has a role in cell cycle-regulated degradation of daughter cell-specific mRNAs; binds to the NME1 RNA subunit of RNase MRP. | Uncharacterized protein JIP4; Protein of unknown function; previously annotated as two separate ORFs, YDR474C and YDR475C, which were merged as a result of corrections to the systematic reference sequence; JIP4 has a paralog, YOR019W, that arose from the whole genome duplication. | 0.758 |
SNM1 | YDR476C | YDR478W | YDR476C | Ribonuclease MRP complex subunit; ribonuclease (RNase) MRP cleaves pre-rRNA and has a role in cell cycle-regulated degradation of daughter cell-specific mRNAs; binds to the NME1 RNA subunit of RNase MRP. | Uncharacterized protein YDR476C; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YDR476C is not an essential gene. | 0.830 |
TPH3 | JIP4 | YJL016W | YDR475C | Uncharacterized protein YJL016W; Putative protein of unknown function; GFP-fusion protein localizes to the cytoplasm; contains two adjacent PH-like domains; conserved in closely related Saccharomyces species. | Uncharacterized protein JIP4; Protein of unknown function; previously annotated as two separate ORFs, YDR474C and YDR475C, which were merged as a result of corrections to the systematic reference sequence; JIP4 has a paralog, YOR019W, that arose from the whole genome duplication. | 0.803 |
TPH3 | YER084W | YJL016W | YER084W | Uncharacterized protein YJL016W; Putative protein of unknown function; GFP-fusion protein localizes to the cytoplasm; contains two adjacent PH-like domains; conserved in closely related Saccharomyces species. | Uncharacterized protein YER084W; Protein of unknown function; expressed at both mRNA and protein levels. | 0.640 |
TPH3 | YHR173C | YJL016W | YHR173C | Uncharacterized protein YJL016W; Putative protein of unknown function; GFP-fusion protein localizes to the cytoplasm; contains two adjacent PH-like domains; conserved in closely related Saccharomyces species. | Uncharacterized protein YHR173C; Protein of unknown function; expressed at both mRNA and protein levels; SWAT-GFP and mCherry fusion proteins localize to the vacuole. | 0.698 |
TPH3 | YNL140C | YJL016W | YNL140C | Uncharacterized protein YJL016W; Putative protein of unknown function; GFP-fusion protein localizes to the cytoplasm; contains two adjacent PH-like domains; conserved in closely related Saccharomyces species. | Uncharacterized protein YNL140C; Protein of unknown function; expressed at both mRNA and protein levels; partially overlaps THO2/YNL139C. | 0.694 |
TPH3 | YOR105W | YJL016W | YOR105W | Uncharacterized protein YJL016W; Putative protein of unknown function; GFP-fusion protein localizes to the cytoplasm; contains two adjacent PH-like domains; conserved in closely related Saccharomyces species. | Uncharacterized protein YOR105W; Protein of unknown function; expressed at both mRNA and protein levels. | 0.692 |
TPH3 | YPR089W | YJL016W | YPR089W | Uncharacterized protein YJL016W; Putative protein of unknown function; GFP-fusion protein localizes to the cytoplasm; contains two adjacent PH-like domains; conserved in closely related Saccharomyces species. | Dilute domain-containing protein YPR089W; Protein of unknown function; exhibits genetic interaction with ERG11 and protein-protein interaction with Hsp82p. | 0.896 |