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SPG3 protein (Saccharomyces cerevisiae) - STRING interaction network
"SPG3" - Protein required for survival at high temperature during stationary phase in Saccharomyces cerevisiae
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
SPG3Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources; Required for survival during stationary phase (127 aa)    
Predicted Functional Partners:
YPR096C
Protein of unknown function; may interact with ribosomes, based on co-purification experiments (100 aa)
           
  0.848
YDR344C
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data (147 aa)
           
  0.848
MBB1
Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; protein detected in large-scale protein-protein interaction studies; May be involved in metabolic processes (108 aa)
           
  0.729
YNR014W
Putative protein of unknown function; expression is cell-cycle regulated, Azf1p-dependent, and heat-inducible (212 aa)
           
  0.697
FMP45
Integral membrane protein localized to mitochondria (untagged protein); required for sporulation and maintaining sphingolipid content; has sequence similarity to SUR7 and YNL194C; Involved in sporulation and affects the sphingolipid composition of the plasma membrane (309 aa)
           
  0.626
SPG5
Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources; Required for survival at high temperature during stationary phase (373 aa)
           
  0.491
YLR108C
Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; YLR108C is not an esssential gene (485 aa)
           
  0.489
HBT1
Substrate of the Hub1p ubiquitin-like protein that localizes to the shmoo tip (mating projection); mutants are defective for mating projection formation, thereby implicating Hbt1p in polarized cell morphogenesis; Polarity-determining protein which forms a conjugate with the ubiquitin-like modifier HUB1. Involved in bud site selection and cellular morphogenesis during conjugation. Required for survival during stationary phase (1046 aa)
           
  0.487
ABM1
Protein of unknown function, required for normal microtubule organization; Required for normal microtubule organization (123 aa)
           
  0.485
ETR1
2-enoyl thioester reductase, member of the medium chain dehydrogenase/reductase family; localized to in mitochondria, where it has a probable role in fatty acid synthesis; Required for respiration and the maintenance of the mitochondrial compartment. Oxidoreductase with a preference for short and medium chain substrates, including trans-2-hexenoyl-CoA (C6), trans-2-decenoyl-CoA (C10), and trans-2-hexadecenoyl-CoA (C16). May play a role in mitochondrial fatty acid synthesis (380 aa)
           
  0.469
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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