node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BI4 | YDR544C | Q0120 | YDR544C | Truncated, nonfunctional cytochrome b; Mitochondrial mRNA maturase; forms a complex with Nam2p to mediate splicing of the bI4 intron of the COB gene; encoded by both exon and intron sequences of partially processed COB mRNA. | Putative uncharacterized protein YDR544C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | 0.448 |
BI4 | YNL013C | Q0120 | YNL013C | Truncated, nonfunctional cytochrome b; Mitochondrial mRNA maturase; forms a complex with Nam2p to mediate splicing of the bI4 intron of the COB gene; encoded by both exon and intron sequences of partially processed COB mRNA. | Putative uncharacterized protein YNL013C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF HEF3/YNL014W. | 0.485 |
SUB1 | YDR544C | YMR039C | YDR544C | Transcriptional regulator; facilitates elongation through factors that modify RNAP II; role in peroxide resistance involving Rad2p; role in nonhomologous end-joining (NHEJ) of ds breaks in plasmid DNA, but not chromosomal DNA; role in the hyperosmotic stress response through polymerase recruitment at RNAP II and RNAP III genes; negatively regulates sporulation; protein abundance increases in response to DNA replication stress; functionally complemented by human SUB1 (PC4). | Putative uncharacterized protein YDR544C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | 0.554 |
TBF1 | YDR544C | YPL128C | YDR544C | Protein TBF1; Telobox-containing general regulatory factor; binds TTAGGG repeats within subtelomeric anti-silencing regions (STARs), blocking silent chromatin propagation; binds majority of snoRNA gene promoters, required for full snoRNA expression; caps DSB flanked by long T2AG3 repeats and blocks checkpoint activation. | Putative uncharacterized protein YDR544C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | 0.757 |
YDL162C | YDR544C | YDL162C | YDR544C | Putative uncharacterized protein YDL162C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps ENT1/YDL161W, a verified gene involved in endocytosis and actin cortical patch assembly. | Putative uncharacterized protein YDR544C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | 0.418 |
YDR543C | YDR544C | YDR543C | YDR544C | Putative UPF0320 protein YDR543C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | Putative uncharacterized protein YDR544C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | 0.907 |
YDR543C | YDR545C-A | YDR543C | YDR545C-A | Putative UPF0320 protein YDR543C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | Putative UPF0479 protein YDR545C-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; completely overlaps the verified ORF YRF1-1/YDR545W; Belongs to the UPF0479 family. | 0.893 |
YDR543C | YHR217C | YDR543C | YHR217C | Putative UPF0320 protein YDR543C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | Putative uncharacterized protein YHR217C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; located in the telomeric region TEL08R. | 0.866 |
YDR543C | YRF1-1 | YDR543C | YDR545W | Putative UPF0320 protein YDR543C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | Y' element ATP-dependent helicase protein 1 copy 1; Helicase encoded by the Y' element of subtelomeric regions; highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p. | 0.846 |
YDR544C | BI4 | YDR544C | Q0120 | Putative uncharacterized protein YDR544C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | Truncated, nonfunctional cytochrome b; Mitochondrial mRNA maturase; forms a complex with Nam2p to mediate splicing of the bI4 intron of the COB gene; encoded by both exon and intron sequences of partially processed COB mRNA. | 0.448 |
YDR544C | SUB1 | YDR544C | YMR039C | Putative uncharacterized protein YDR544C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | Transcriptional regulator; facilitates elongation through factors that modify RNAP II; role in peroxide resistance involving Rad2p; role in nonhomologous end-joining (NHEJ) of ds breaks in plasmid DNA, but not chromosomal DNA; role in the hyperosmotic stress response through polymerase recruitment at RNAP II and RNAP III genes; negatively regulates sporulation; protein abundance increases in response to DNA replication stress; functionally complemented by human SUB1 (PC4). | 0.554 |
YDR544C | TBF1 | YDR544C | YPL128C | Putative uncharacterized protein YDR544C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | Protein TBF1; Telobox-containing general regulatory factor; binds TTAGGG repeats within subtelomeric anti-silencing regions (STARs), blocking silent chromatin propagation; binds majority of snoRNA gene promoters, required for full snoRNA expression; caps DSB flanked by long T2AG3 repeats and blocks checkpoint activation. | 0.757 |
YDR544C | YDL162C | YDR544C | YDL162C | Putative uncharacterized protein YDR544C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | Putative uncharacterized protein YDL162C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps ENT1/YDL161W, a verified gene involved in endocytosis and actin cortical patch assembly. | 0.418 |
YDR544C | YDR543C | YDR544C | YDR543C | Putative uncharacterized protein YDR544C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | Putative UPF0320 protein YDR543C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | 0.907 |
YDR544C | YDR545C-A | YDR544C | YDR545C-A | Putative uncharacterized protein YDR544C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | Putative UPF0479 protein YDR545C-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; completely overlaps the verified ORF YRF1-1/YDR545W; Belongs to the UPF0479 family. | 0.893 |
YDR544C | YHR217C | YDR544C | YHR217C | Putative uncharacterized protein YDR544C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | Putative uncharacterized protein YHR217C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; located in the telomeric region TEL08R. | 0.470 |
YDR544C | YLR282C | YDR544C | YLR282C | Putative uncharacterized protein YDR544C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | Putative uncharacterized protein YLR282C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; deletion mutation confers an increase in Ty1 transposition. | 0.465 |
YDR544C | YNL013C | YDR544C | YNL013C | Putative uncharacterized protein YDR544C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | Putative uncharacterized protein YNL013C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF HEF3/YNL014W. | 0.447 |
YDR544C | YRF1-1 | YDR544C | YDR545W | Putative uncharacterized protein YDR544C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | Y' element ATP-dependent helicase protein 1 copy 1; Helicase encoded by the Y' element of subtelomeric regions; highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p. | 0.846 |
YDR545C-A | YDR543C | YDR545C-A | YDR543C | Putative UPF0479 protein YDR545C-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; completely overlaps the verified ORF YRF1-1/YDR545W; Belongs to the UPF0479 family. | Putative UPF0320 protein YDR543C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | 0.893 |