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YEA4 protein (Saccharomyces cerevisiae) - STRING interaction network
"YEA4" - Uridine diphosphate-N-acetylglucosamine in Saccharomyces cerevisiae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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YEA4Uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) transporter required for cell wall chitin synthesis; localized to the ER; Sugar transporter that specifically mediates the transport of UDP-N-acetylglucosamine (UDP-GlcNAc) and is required for cell wall chitin synthesis (342 aa)    
Predicted Functional Partners:
HUT1
Protein with a role in UDP-galactose transport to the Golgi lumen, has similarity to human UDP-galactose transporter UGTrel1, exhibits a genetic interaction with S. cerevisiae ERO1; May be involved in specific transport of UDP-Gal from the cytosol to the Golgi lumen. Involved in the maintenance of optimal conditions for the folding of secretory pathway proteins in the endoplasmic reticulum. Overexpression confers resistance to the immunosuppressive drug, leflunomide (339 aa)
           
  0.811
YMD8
Putative nucleotide sugar transporter, has similarity to Vrg4p (442 aa)
           
  0.796
MRPL24
Mitochondrial ribosomal protein of the large subunit; two mitochondrial ribosomal proteins, YmL14 and YmL24, have been assigned to the same gene (258 aa)
           
  0.680
VRG4
Golgi GDP-mannose transporter; regulates Golgi function and glycosylation in Golgi; Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen. Defective copy causes severe glycosylation defect and abnormal retention of soluble endoplasmic reticulum proteins. Involved in vanadate sensitivity (337 aa)
           
  0.616
APA1
Diadenosine 5’,5’’-P1,P4-tetraphosphate phosphorylase I (AP4A phosphorylase), involved in catabolism of bis(5’-nucleosidyl) tetraphosphates; has similarity to Apa2p; Ap4A phosphorylase catalyzes the phosphorolytic degradation of bis(5’-adenosyl) tetraphosphate (Ap4A) into ADP and ATP. Can also use other Np4N’ nucleotides (where N and N’ stand for A,C,G or U) as substrates with equal efficiency. Cannot catalyze the reverse reaction. Additionally, this enzyme can also catalyze the phosphorolytic degradation of adenosine 5’- phosphosulfate (AMPS) into ADP and sulfate, the reversible excha [...] (321 aa)
           
  0.578
PAL1
Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and bud neck; potential Cdc28p substrate; Involved in the early step of endocytosis (499 aa)
           
  0.572
MRPL11
Mitochondrial ribosomal protein of the large subunit (249 aa)
           
  0.483
YPR098C
Protein of unknown function, localized to the mitochondrial outer membrane (161 aa)
           
  0.441
YMR253C
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; YMR253C is not an essential gene (414 aa)
           
  0.431
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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