Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RML2Mitochondrial ribosomal protein of the large subunit (L2); has similarity to E. coli L2 ribosomal protein; mutant allele (fat21) causes inability to utilize oleate, and induce oleic acid oxidation; may interfere with activity of the Adr1p transcription factor. (393 aa)    
Predicted Functional Partners:
IMG1
Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome.
   
 
 0.999
MRPL9
Mitochondrial ribosomal protein of the large subunit.
 
 0.998
MRPL16
Mitochondrial ribosomal protein of the large subunit; homologous to bacterial L16 ribosomal protein; synthetic lethality with hac1 mutation suggests a possible role in synthesis of precursors for protein glycosylation.
  
 
 0.997
MRPL8
Mitochondrial ribosomal protein of the large subunit.
  
 
 0.997
MRPL22
Mitochondrial ribosomal protein of the large subunit.
  
 
 0.997
MRPS18
Mitochondrial ribosomal protein of the small subunit; essential for viability, unlike most other mitoribosomal proteins.
  
 
 0.997
RTC6
54S ribosomal protein RTC6, mitochondrial; Protein involved in translation; mutants have defects in biogenesis of nuclear ribosomes; sequence similar to prokaryotic ribosomal protein L36, may be a mitochondrial ribosomal protein; protein abundance increases in response to DNA replication stress; Belongs to the bacterial ribosomal protein bL36 family.
  
 
 0.997
RSM18
Mitochondrial ribosomal protein of the small subunit; has similarity to E. coli S18 ribosomal protein.
   
 
 0.996
MRP4
Mitochondrial ribosomal protein of the small subunit.
  
 
 0.996
MRPL6
Mitochondrial ribosomal protein of the large subunit.
  
 
 0.996
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: ATCC 18824, Candida robusta, Mycoderma cerevisiae, NRRL Y-12632, S. cerevisiae, Saccharomyces capensis, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, yeast
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