node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADE8 | HOM3 | YDR408C | YER052C | Phosphoribosylglycinamide formyltransferase; Phosphoribosyl-glycinamide transformylase; catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway | Aspartokinase; Aspartate kinase (L-aspartate 4-P-transferase); cytoplasmic enzyme that catalyzes the first step in the common pathway for methionine and threonine biosynthesis; expression regulated by Gcn4p and the general control of amino acid synthesis; Belongs to the aspartokinase family | 0.901 |
ADE8 | HXT13 | YDR408C | YEL069C | Phosphoribosylglycinamide formyltransferase; Phosphoribosyl-glycinamide transformylase; catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway | Mfs transporter, sp family, sugar:h+ symporter; Hexose transporter HXT13; Putative transmembrane polyol transporter; supports growth on and uptake of mannitol and sorbitol with moderate affinity when overexpressed in a strain deleted for hexose family members; minor hexose transport activity when overexpressed in a similar strain; induced by non-fermentable carbon sources; induced in low glucose, repressed in high glucose; HXT13 has a paralog, HXT17, that arose from a segmental duplication | 0.896 |
ADE8 | RMD6 | YDR408C | YEL072W | Phosphoribosylglycinamide formyltransferase; Phosphoribosyl-glycinamide transformylase; catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway | Sporulation protein rmd6; Required for sporulation. Required for meiotic nuclear division | 0.750 |
ADE8 | YEL068C | YDR408C | YEL068C | Phosphoribosylglycinamide formyltransferase; Phosphoribosyl-glycinamide transformylase; catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway | Uncharacterized protein YEL068C; Protein of unknown function; expressed at both mRNA and protein levels; SWAT-GFP and seamless-GFP fusion proteins localize to the endoplasmic reticulum and mCherry fusion protein localizes to the vacuole | 0.760 |
DSF1 | HXT13 | YEL070W | YEL069C | Mannitol dehydrogenase; deletion suppresses mutation of mpt5; DSF1 has a paralog, MAN2, that arose from a segmental duplication | Mfs transporter, sp family, sugar:h+ symporter; Hexose transporter HXT13; Putative transmembrane polyol transporter; supports growth on and uptake of mannitol and sorbitol with moderate affinity when overexpressed in a strain deleted for hexose family members; minor hexose transport activity when overexpressed in a similar strain; induced by non-fermentable carbon sources; induced in low glucose, repressed in high glucose; HXT13 has a paralog, HXT17, that arose from a segmental duplication | 0.837 |
DSF1 | MAN2 | YEL070W | YNR073C | Mannitol dehydrogenase; deletion suppresses mutation of mpt5; DSF1 has a paralog, MAN2, that arose from a segmental duplication | Mannitol dehydrogenase; MAN2 has a paralog, DSF1, that arose from a segmental duplication | 0.872 |
DSF1 | RMD6 | YEL070W | YEL072W | Mannitol dehydrogenase; deletion suppresses mutation of mpt5; DSF1 has a paralog, MAN2, that arose from a segmental duplication | Sporulation protein rmd6; Required for sporulation. Required for meiotic nuclear division | 0.813 |
DSF1 | YEL068C | YEL070W | YEL068C | Mannitol dehydrogenase; deletion suppresses mutation of mpt5; DSF1 has a paralog, MAN2, that arose from a segmental duplication | Uncharacterized protein YEL068C; Protein of unknown function; expressed at both mRNA and protein levels; SWAT-GFP and seamless-GFP fusion proteins localize to the endoplasmic reticulum and mCherry fusion protein localizes to the vacuole | 0.813 |
HOM3 | ADE8 | YER052C | YDR408C | Aspartokinase; Aspartate kinase (L-aspartate 4-P-transferase); cytoplasmic enzyme that catalyzes the first step in the common pathway for methionine and threonine biosynthesis; expression regulated by Gcn4p and the general control of amino acid synthesis; Belongs to the aspartokinase family | Phosphoribosylglycinamide formyltransferase; Phosphoribosyl-glycinamide transformylase; catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway | 0.901 |
HOM3 | HXT13 | YER052C | YEL069C | Aspartokinase; Aspartate kinase (L-aspartate 4-P-transferase); cytoplasmic enzyme that catalyzes the first step in the common pathway for methionine and threonine biosynthesis; expression regulated by Gcn4p and the general control of amino acid synthesis; Belongs to the aspartokinase family | Mfs transporter, sp family, sugar:h+ symporter; Hexose transporter HXT13; Putative transmembrane polyol transporter; supports growth on and uptake of mannitol and sorbitol with moderate affinity when overexpressed in a strain deleted for hexose family members; minor hexose transport activity when overexpressed in a similar strain; induced by non-fermentable carbon sources; induced in low glucose, repressed in high glucose; HXT13 has a paralog, HXT17, that arose from a segmental duplication | 0.890 |
HOM3 | RMD6 | YER052C | YEL072W | Aspartokinase; Aspartate kinase (L-aspartate 4-P-transferase); cytoplasmic enzyme that catalyzes the first step in the common pathway for methionine and threonine biosynthesis; expression regulated by Gcn4p and the general control of amino acid synthesis; Belongs to the aspartokinase family | Sporulation protein rmd6; Required for sporulation. Required for meiotic nuclear division | 0.750 |
HOM3 | YEL068C | YER052C | YEL068C | Aspartokinase; Aspartate kinase (L-aspartate 4-P-transferase); cytoplasmic enzyme that catalyzes the first step in the common pathway for methionine and threonine biosynthesis; expression regulated by Gcn4p and the general control of amino acid synthesis; Belongs to the aspartokinase family | Uncharacterized protein YEL068C; Protein of unknown function; expressed at both mRNA and protein levels; SWAT-GFP and seamless-GFP fusion proteins localize to the endoplasmic reticulum and mCherry fusion protein localizes to the vacuole | 0.748 |
HXT13 | ADE8 | YEL069C | YDR408C | Mfs transporter, sp family, sugar:h+ symporter; Hexose transporter HXT13; Putative transmembrane polyol transporter; supports growth on and uptake of mannitol and sorbitol with moderate affinity when overexpressed in a strain deleted for hexose family members; minor hexose transport activity when overexpressed in a similar strain; induced by non-fermentable carbon sources; induced in low glucose, repressed in high glucose; HXT13 has a paralog, HXT17, that arose from a segmental duplication | Phosphoribosylglycinamide formyltransferase; Phosphoribosyl-glycinamide transformylase; catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway | 0.896 |
HXT13 | DSF1 | YEL069C | YEL070W | Mfs transporter, sp family, sugar:h+ symporter; Hexose transporter HXT13; Putative transmembrane polyol transporter; supports growth on and uptake of mannitol and sorbitol with moderate affinity when overexpressed in a strain deleted for hexose family members; minor hexose transport activity when overexpressed in a similar strain; induced by non-fermentable carbon sources; induced in low glucose, repressed in high glucose; HXT13 has a paralog, HXT17, that arose from a segmental duplication | Mannitol dehydrogenase; deletion suppresses mutation of mpt5; DSF1 has a paralog, MAN2, that arose from a segmental duplication | 0.837 |
HXT13 | HOM3 | YEL069C | YER052C | Mfs transporter, sp family, sugar:h+ symporter; Hexose transporter HXT13; Putative transmembrane polyol transporter; supports growth on and uptake of mannitol and sorbitol with moderate affinity when overexpressed in a strain deleted for hexose family members; minor hexose transport activity when overexpressed in a similar strain; induced by non-fermentable carbon sources; induced in low glucose, repressed in high glucose; HXT13 has a paralog, HXT17, that arose from a segmental duplication | Aspartokinase; Aspartate kinase (L-aspartate 4-P-transferase); cytoplasmic enzyme that catalyzes the first step in the common pathway for methionine and threonine biosynthesis; expression regulated by Gcn4p and the general control of amino acid synthesis; Belongs to the aspartokinase family | 0.890 |
HXT13 | MAN2 | YEL069C | YNR073C | Mfs transporter, sp family, sugar:h+ symporter; Hexose transporter HXT13; Putative transmembrane polyol transporter; supports growth on and uptake of mannitol and sorbitol with moderate affinity when overexpressed in a strain deleted for hexose family members; minor hexose transport activity when overexpressed in a similar strain; induced by non-fermentable carbon sources; induced in low glucose, repressed in high glucose; HXT13 has a paralog, HXT17, that arose from a segmental duplication | Mannitol dehydrogenase; MAN2 has a paralog, DSF1, that arose from a segmental duplication | 0.857 |
HXT13 | RMD6 | YEL069C | YEL072W | Mfs transporter, sp family, sugar:h+ symporter; Hexose transporter HXT13; Putative transmembrane polyol transporter; supports growth on and uptake of mannitol and sorbitol with moderate affinity when overexpressed in a strain deleted for hexose family members; minor hexose transport activity when overexpressed in a similar strain; induced by non-fermentable carbon sources; induced in low glucose, repressed in high glucose; HXT13 has a paralog, HXT17, that arose from a segmental duplication | Sporulation protein rmd6; Required for sporulation. Required for meiotic nuclear division | 0.765 |
HXT13 | YEL068C | YEL069C | YEL068C | Mfs transporter, sp family, sugar:h+ symporter; Hexose transporter HXT13; Putative transmembrane polyol transporter; supports growth on and uptake of mannitol and sorbitol with moderate affinity when overexpressed in a strain deleted for hexose family members; minor hexose transport activity when overexpressed in a similar strain; induced by non-fermentable carbon sources; induced in low glucose, repressed in high glucose; HXT13 has a paralog, HXT17, that arose from a segmental duplication | Uncharacterized protein YEL068C; Protein of unknown function; expressed at both mRNA and protein levels; SWAT-GFP and seamless-GFP fusion proteins localize to the endoplasmic reticulum and mCherry fusion protein localizes to the vacuole | 0.779 |
MAN2 | DSF1 | YNR073C | YEL070W | Mannitol dehydrogenase; MAN2 has a paralog, DSF1, that arose from a segmental duplication | Mannitol dehydrogenase; deletion suppresses mutation of mpt5; DSF1 has a paralog, MAN2, that arose from a segmental duplication | 0.872 |
MAN2 | HXT13 | YNR073C | YEL069C | Mannitol dehydrogenase; MAN2 has a paralog, DSF1, that arose from a segmental duplication | Mfs transporter, sp family, sugar:h+ symporter; Hexose transporter HXT13; Putative transmembrane polyol transporter; supports growth on and uptake of mannitol and sorbitol with moderate affinity when overexpressed in a strain deleted for hexose family members; minor hexose transport activity when overexpressed in a similar strain; induced by non-fermentable carbon sources; induced in low glucose, repressed in high glucose; HXT13 has a paralog, HXT17, that arose from a segmental duplication | 0.857 |