STRINGSTRING
YER010C protein (Saccharomyces cerevisiae) - STRING interaction network
"YER010C" - Protein of unknown function, forms a ring-shaped homotrimer in Saccharomyces cerevisiae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YER010CProtein of unknown function, forms a ring-shaped homotrimer; has similarity to members of the prokaryotic rraA family; possibly involved in a phosphotransfer reaction; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (234 aa)    
Predicted Functional Partners:
YPR204W
Helicase-like protein encoded within the telomeric Y’ element; Catalyzes DNA unwinding and is involved in telomerase- independent telomere maintenance (1032 aa)
       
 
  0.766
YRF1-7
Helicase encoded by the Y’ element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p; Catalyzes DNA unwinding and is involved in telomerase- independent telomere maintenance (1859 aa)
       
 
  0.766
YRF1-8
One of several telomeric Y’ element-encoded DNA helicases, known as Y’-Help1 (Y’-HELicase Protein 1); Catalyzes DNA unwinding and is involved in telomerase- independent telomere maintenance (1796 aa)
       
 
  0.766
YRF1-6
Helicase encoded by the Y’ element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p (1859 aa)
       
 
  0.766
DBP2
Essential ATP-dependent RNA helicase of the DEAD-box protein family, involved in nonsense-mediated mRNA decay and rRNA processing; ATP-dependent RNA helicase involved nonsense-mediated mRNA decay and ribosome biogenesis through rRNA processing (546 aa)
       
 
  0.766
HAS1
ATP-dependent RNA helicase; localizes to both the nuclear periphery and nucleolus; highly enriched in nuclear pore complex fractions; constituent of 66S pre-ribosomal particles; ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA (505 aa)
       
 
  0.766
YML133C
Putative Y’ element ATP-dependent helicase; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YML133C contains an intron; Catalyzes DNA unwinding and is involved in telomerase- independent telomere maintenance (1374 aa)
       
 
  0.766
YRF1-5
Helicase encoded by the Y’ element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p; Catalyzes DNA unwinding and is involved in telomerase- independent telomere maintenance (1796 aa)
       
 
  0.766
YRF1-4
Helicase encoded by the Y’ element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p; Catalyzes DNA unwinding and is involved in telomerase- independent telomere maintenance (1382 aa)
       
 
  0.766
YLL067C
Putative Y’ element ATP-dependent helicase (1205 aa)
       
 
  0.766
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
Server load: low (13%) [HD]