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YER034W protein (Saccharomyces cerevisiae) - STRING interaction network
"YER034W" - Putative protein of unknown function in Saccharomyces cerevisiae
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
YER034WPutative protein of unknown function; non-essential gene; expression induced upon calcium shortage (185 aa)    
Predicted Functional Partners:
YIL108W
Putative metalloprotease (696 aa)
           
  0.897
SDH8
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Binds to the flavoprotein subunit SDH1 in its FAD-bound form, blocking the generati [...] (138 aa)
           
  0.892
KCH1
Vacuolar protein of unknown function; potential Cdc28p substrate (497 aa)
           
  0.700
ZRG8
Protein of unknown function; authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; GFP-fusion protein is localized to the cytoplasm; transcription induced under conditions of zinc deficiency; Involved in the integrity functions of RAM, a conserved signaling network that regulates maintenance of polarized growth and daughter-cell-specific transcription (1076 aa)
           
  0.698
BOP3
Protein of unknown function, potential Cdc28p substrate; overproduction confers resistance to methylmercury; Involved in resistance to methylmercury. Overexpression suppresses a PAM1-SLV3 double null mutation (396 aa)
           
  0.640
CMS1
Putative subunit of the 90S preribosome processome complex; overexpression rescues supressor mutant of mcm10; null mutant is viable; relocalizes from nucleus to cytoplasm upon DNA replication stress; May play a role in the regulation of DNA replication and cell cycle control (291 aa)
           
  0.580
ULI1
Putative protein of unknown function involved in and induced by the endoplasmic reticulum unfolded protein response; Involved in the unfolded protein response (UPR), a transcriptional response which up-regulates genes that enable cells to cope with misfolded, endoplasmic reticulum-retained proteins. UPR is part of the endoplasmic reticulum quality control (ERQC) which prevents the exit of misfolded secretory and membrane proteins from the endoplasmic reticulum (169 aa)
           
  0.578
SBE22
Protein involved in the transport of cell wall components from the Golgi to the cell surface; similar in structure and functionally redundant with Sbe2p; involved in bud growth; With SBE2, is involved in cell wall integrity and polarity processes like bud growth, through the transport of CHS3 and UTR2 to sites of growth (852 aa)
           
  0.508
BRN1
Subunit of the condensin complex; required for chromosome condensation and for clustering of tRNA genes at the nucleolus; may influence multiple aspects of chromosome transmission; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. The condensin complex probably also plays a role duri [...] (754 aa)
           
  0.489
PAC2
Microtubule effector required for tubulin heterodimer formation, binds alpha-tubulin, required for normal microtubule function, null mutant exhibits cold-sensitive microtubules and sensitivity to benomyl; Required for viability in the absence of the kinesin- related CIN8 mitotic motor. Seems to be involved in the assembly of alpha-tubulin (518 aa)
           
  0.485
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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