| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BOP3 | YER034W | YNL042W | YER034W | Protein of unknown function; potential Cdc28p substrate; overproduction confers resistance to methylmercury. | Uncharacterized protein YER034W; Protein of unknown function; non-essential gene; expression induced upon calcium shortage; protein abundance increases in response to DNA replication stress. | 0.816 |
| BOP3 | YIL108W | YNL042W | YIL108W | Protein of unknown function; potential Cdc28p substrate; overproduction confers resistance to methylmercury. | Putative zinc metalloproteinase YIL108W; Putative metalloendopeptidase; forms cytoplasmic foci upon DNA replication stress; Belongs to the peptidase M10B family. | 0.666 |
| ECM33 | YER034W | YBR078W | YER034W | Cell wall protein ECM33; GPI-anchored protein of unknown function; possible role in apical bud growth; GPI-anchoring on the plasma membrane crucial to function; phosphorylated in mitochondria; similar to Sps2p; ECM33 has a paralog, PST1, that arose from the whole genome duplication. | Uncharacterized protein YER034W; Protein of unknown function; non-essential gene; expression induced upon calcium shortage; protein abundance increases in response to DNA replication stress. | 0.430 |
| PRM5 | SDH8 | YIL117C | YBR269C | Pheromone-regulated protein, predicted to have 1 transmembrane segment; induced during cell integrity signaling; PRM5 has a paralog, YNL058C, that arose from the whole genome duplication. | Protein required for assembly of succinate dehydrogenase; interacts with flavinylated Sdh1p and may function as a chaperone for free Sdh1p, protecting its FAD cofactor from redox reactions before assembly of the complex; soluble protein of the mitochondrial matrix; respiratory defect of null mutant is functionally complemented by Drosophila and human orthologs. | 0.409 |
| PRM5 | YER034W | YIL117C | YER034W | Pheromone-regulated protein, predicted to have 1 transmembrane segment; induced during cell integrity signaling; PRM5 has a paralog, YNL058C, that arose from the whole genome duplication. | Uncharacterized protein YER034W; Protein of unknown function; non-essential gene; expression induced upon calcium shortage; protein abundance increases in response to DNA replication stress. | 0.647 |
| RTT101 | YER034W | YJL047C | YER034W | Cullin-8; Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex; role in anaphase progression; required for recovery after DSB repair; implicated in Mms22-dependent DNA repair; involved with Mms1p in nonfunctional rRNA decay; modified by the ubiquitin-like protein, Rub1p. | Uncharacterized protein YER034W; Protein of unknown function; non-essential gene; expression induced upon calcium shortage; protein abundance increases in response to DNA replication stress. | 0.462 |
| SAM1 | YER034W | YLR180W | YER034W | S-adenosylmethionine synthase 1; S-adenosylmethionine synthetase; catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine; SAM1 has a paralog, SAM2, that arose from the whole genome duplication. | Uncharacterized protein YER034W; Protein of unknown function; non-essential gene; expression induced upon calcium shortage; protein abundance increases in response to DNA replication stress. | 0.418 |
| SDH8 | PRM5 | YBR269C | YIL117C | Protein required for assembly of succinate dehydrogenase; interacts with flavinylated Sdh1p and may function as a chaperone for free Sdh1p, protecting its FAD cofactor from redox reactions before assembly of the complex; soluble protein of the mitochondrial matrix; respiratory defect of null mutant is functionally complemented by Drosophila and human orthologs. | Pheromone-regulated protein, predicted to have 1 transmembrane segment; induced during cell integrity signaling; PRM5 has a paralog, YNL058C, that arose from the whole genome duplication. | 0.409 |
| SDH8 | YER034W | YBR269C | YER034W | Protein required for assembly of succinate dehydrogenase; interacts with flavinylated Sdh1p and may function as a chaperone for free Sdh1p, protecting its FAD cofactor from redox reactions before assembly of the complex; soluble protein of the mitochondrial matrix; respiratory defect of null mutant is functionally complemented by Drosophila and human orthologs. | Uncharacterized protein YER034W; Protein of unknown function; non-essential gene; expression induced upon calcium shortage; protein abundance increases in response to DNA replication stress. | 0.835 |
| YER034W | BOP3 | YER034W | YNL042W | Uncharacterized protein YER034W; Protein of unknown function; non-essential gene; expression induced upon calcium shortage; protein abundance increases in response to DNA replication stress. | Protein of unknown function; potential Cdc28p substrate; overproduction confers resistance to methylmercury. | 0.816 |
| YER034W | ECM33 | YER034W | YBR078W | Uncharacterized protein YER034W; Protein of unknown function; non-essential gene; expression induced upon calcium shortage; protein abundance increases in response to DNA replication stress. | Cell wall protein ECM33; GPI-anchored protein of unknown function; possible role in apical bud growth; GPI-anchoring on the plasma membrane crucial to function; phosphorylated in mitochondria; similar to Sps2p; ECM33 has a paralog, PST1, that arose from the whole genome duplication. | 0.430 |
| YER034W | PRM5 | YER034W | YIL117C | Uncharacterized protein YER034W; Protein of unknown function; non-essential gene; expression induced upon calcium shortage; protein abundance increases in response to DNA replication stress. | Pheromone-regulated protein, predicted to have 1 transmembrane segment; induced during cell integrity signaling; PRM5 has a paralog, YNL058C, that arose from the whole genome duplication. | 0.647 |
| YER034W | RTT101 | YER034W | YJL047C | Uncharacterized protein YER034W; Protein of unknown function; non-essential gene; expression induced upon calcium shortage; protein abundance increases in response to DNA replication stress. | Cullin-8; Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex; role in anaphase progression; required for recovery after DSB repair; implicated in Mms22-dependent DNA repair; involved with Mms1p in nonfunctional rRNA decay; modified by the ubiquitin-like protein, Rub1p. | 0.462 |
| YER034W | SAM1 | YER034W | YLR180W | Uncharacterized protein YER034W; Protein of unknown function; non-essential gene; expression induced upon calcium shortage; protein abundance increases in response to DNA replication stress. | S-adenosylmethionine synthase 1; S-adenosylmethionine synthetase; catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine; SAM1 has a paralog, SAM2, that arose from the whole genome duplication. | 0.418 |
| YER034W | SDH8 | YER034W | YBR269C | Uncharacterized protein YER034W; Protein of unknown function; non-essential gene; expression induced upon calcium shortage; protein abundance increases in response to DNA replication stress. | Protein required for assembly of succinate dehydrogenase; interacts with flavinylated Sdh1p and may function as a chaperone for free Sdh1p, protecting its FAD cofactor from redox reactions before assembly of the complex; soluble protein of the mitochondrial matrix; respiratory defect of null mutant is functionally complemented by Drosophila and human orthologs. | 0.835 |
| YER034W | YIL108W | YER034W | YIL108W | Uncharacterized protein YER034W; Protein of unknown function; non-essential gene; expression induced upon calcium shortage; protein abundance increases in response to DNA replication stress. | Putative zinc metalloproteinase YIL108W; Putative metalloendopeptidase; forms cytoplasmic foci upon DNA replication stress; Belongs to the peptidase M10B family. | 0.893 |
| YIL108W | BOP3 | YIL108W | YNL042W | Putative zinc metalloproteinase YIL108W; Putative metalloendopeptidase; forms cytoplasmic foci upon DNA replication stress; Belongs to the peptidase M10B family. | Protein of unknown function; potential Cdc28p substrate; overproduction confers resistance to methylmercury. | 0.666 |
| YIL108W | YER034W | YIL108W | YER034W | Putative zinc metalloproteinase YIL108W; Putative metalloendopeptidase; forms cytoplasmic foci upon DNA replication stress; Belongs to the peptidase M10B family. | Uncharacterized protein YER034W; Protein of unknown function; non-essential gene; expression induced upon calcium shortage; protein abundance increases in response to DNA replication stress. | 0.893 |
