| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACT1 | HVG1 | YFL039C | YER039C | Actin; structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions. | Probable GDP-mannose transporter 2; Protein of unknown function; HVG1 has a paralog, VRG4, that arose from the whole genome duplication; Belongs to the TPT transporter family. SLC35D subfamily. | 0.561 |
| ACT1 | VRG4 | YFL039C | YGL225W | Actin; structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions. | Golgi GDP-mannose transporter; regulates Golgi function and glycosylation in Golgi; VRG4 has a paralog, HVG1, that arose from the whole genome duplication; Belongs to the TPT transporter family. SLC35D subfamily. | 0.577 |
| ACT1 | YER039C-A | YFL039C | YER039C-A | Actin; structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions. | Putative protein of unknown function; YER039C-A is not an essential gene; Belongs to the TPT transporter family. SLC35D subfamily. | 0.423 |
| FMP49 | HVG1 | YER038W-A | YER039C | Mitochondrial protein of unknown function; almost completely overlaps ORF HVG1/YER039C. | Probable GDP-mannose transporter 2; Protein of unknown function; HVG1 has a paralog, VRG4, that arose from the whole genome duplication; Belongs to the TPT transporter family. SLC35D subfamily. | 0.806 |
| HUT1 | HVG1 | YPL244C | YER039C | UDP-galactose transporter homolog 1; Protein with a role in UDP-galactose transport to the Golgi lumen; has similarity to human UDP-galactose transporter UGTrel1, exhibits a genetic interaction with S. cerevisiae ERO1; Belongs to the nucleotide-sugar transporter family. SLC35B subfamily. | Probable GDP-mannose transporter 2; Protein of unknown function; HVG1 has a paralog, VRG4, that arose from the whole genome duplication; Belongs to the TPT transporter family. SLC35D subfamily. | 0.653 |
| HUT1 | THI74 | YPL244C | YDR438W | UDP-galactose transporter homolog 1; Protein with a role in UDP-galactose transport to the Golgi lumen; has similarity to human UDP-galactose transporter UGTrel1, exhibits a genetic interaction with S. cerevisiae ERO1; Belongs to the nucleotide-sugar transporter family. SLC35B subfamily. | Mitochondrial transporter repressible by thiamine; THI74 has a paralog, YML018C, that arose from the whole genome duplication; shows sequence homology to human gene SLC35F3, a thiamine transporter implicated in hypertension. | 0.778 |
| HUT1 | VRG4 | YPL244C | YGL225W | UDP-galactose transporter homolog 1; Protein with a role in UDP-galactose transport to the Golgi lumen; has similarity to human UDP-galactose transporter UGTrel1, exhibits a genetic interaction with S. cerevisiae ERO1; Belongs to the nucleotide-sugar transporter family. SLC35B subfamily. | Golgi GDP-mannose transporter; regulates Golgi function and glycosylation in Golgi; VRG4 has a paralog, HVG1, that arose from the whole genome duplication; Belongs to the TPT transporter family. SLC35D subfamily. | 0.598 |
| HUT1 | YEA4 | YPL244C | YEL004W | UDP-galactose transporter homolog 1; Protein with a role in UDP-galactose transport to the Golgi lumen; has similarity to human UDP-galactose transporter UGTrel1, exhibits a genetic interaction with S. cerevisiae ERO1; Belongs to the nucleotide-sugar transporter family. SLC35B subfamily. | UDP-N-acetylglucosamine transporter YEA4; Uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) transporter; required for cell wall chitin synthesis; localized to the ER; Belongs to the nucleotide-sugar transporter family. SLC35B subfamily. | 0.840 |
| HUT1 | YMD8 | YPL244C | YML038C | UDP-galactose transporter homolog 1; Protein with a role in UDP-galactose transport to the Golgi lumen; has similarity to human UDP-galactose transporter UGTrel1, exhibits a genetic interaction with S. cerevisiae ERO1; Belongs to the nucleotide-sugar transporter family. SLC35B subfamily. | Putative nucleotide sugar transporter; has similarity to Vrg4p. | 0.913 |
| HVG1 | ACT1 | YER039C | YFL039C | Probable GDP-mannose transporter 2; Protein of unknown function; HVG1 has a paralog, VRG4, that arose from the whole genome duplication; Belongs to the TPT transporter family. SLC35D subfamily. | Actin; structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions. | 0.561 |
| HVG1 | FMP49 | YER039C | YER038W-A | Probable GDP-mannose transporter 2; Protein of unknown function; HVG1 has a paralog, VRG4, that arose from the whole genome duplication; Belongs to the TPT transporter family. SLC35D subfamily. | Mitochondrial protein of unknown function; almost completely overlaps ORF HVG1/YER039C. | 0.806 |
| HVG1 | HUT1 | YER039C | YPL244C | Probable GDP-mannose transporter 2; Protein of unknown function; HVG1 has a paralog, VRG4, that arose from the whole genome duplication; Belongs to the TPT transporter family. SLC35D subfamily. | UDP-galactose transporter homolog 1; Protein with a role in UDP-galactose transport to the Golgi lumen; has similarity to human UDP-galactose transporter UGTrel1, exhibits a genetic interaction with S. cerevisiae ERO1; Belongs to the nucleotide-sugar transporter family. SLC35B subfamily. | 0.653 |
| HVG1 | PSA1 | YER039C | YDL055C | Probable GDP-mannose transporter 2; Protein of unknown function; HVG1 has a paralog, VRG4, that arose from the whole genome duplication; Belongs to the TPT transporter family. SLC35D subfamily. | GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase); synthesizes GDP-mannose from GTP and mannose-1-phosphate in cell wall biosynthesis; required for normal cell wall structure. | 0.611 |
| HVG1 | THI74 | YER039C | YDR438W | Probable GDP-mannose transporter 2; Protein of unknown function; HVG1 has a paralog, VRG4, that arose from the whole genome duplication; Belongs to the TPT transporter family. SLC35D subfamily. | Mitochondrial transporter repressible by thiamine; THI74 has a paralog, YML018C, that arose from the whole genome duplication; shows sequence homology to human gene SLC35F3, a thiamine transporter implicated in hypertension. | 0.595 |
| HVG1 | VRG4 | YER039C | YGL225W | Probable GDP-mannose transporter 2; Protein of unknown function; HVG1 has a paralog, VRG4, that arose from the whole genome duplication; Belongs to the TPT transporter family. SLC35D subfamily. | Golgi GDP-mannose transporter; regulates Golgi function and glycosylation in Golgi; VRG4 has a paralog, HVG1, that arose from the whole genome duplication; Belongs to the TPT transporter family. SLC35D subfamily. | 0.545 |
| HVG1 | YEA4 | YER039C | YEL004W | Probable GDP-mannose transporter 2; Protein of unknown function; HVG1 has a paralog, VRG4, that arose from the whole genome duplication; Belongs to the TPT transporter family. SLC35D subfamily. | UDP-N-acetylglucosamine transporter YEA4; Uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) transporter; required for cell wall chitin synthesis; localized to the ER; Belongs to the nucleotide-sugar transporter family. SLC35B subfamily. | 0.551 |
| HVG1 | YER039C-A | YER039C | YER039C-A | Probable GDP-mannose transporter 2; Protein of unknown function; HVG1 has a paralog, VRG4, that arose from the whole genome duplication; Belongs to the TPT transporter family. SLC35D subfamily. | Putative protein of unknown function; YER039C-A is not an essential gene; Belongs to the TPT transporter family. SLC35D subfamily. | 0.834 |
| HVG1 | YMD8 | YER039C | YML038C | Probable GDP-mannose transporter 2; Protein of unknown function; HVG1 has a paralog, VRG4, that arose from the whole genome duplication; Belongs to the TPT transporter family. SLC35D subfamily. | Putative nucleotide sugar transporter; has similarity to Vrg4p. | 0.710 |
| HVG1 | YOL162W | YER039C | YOL162W | Probable GDP-mannose transporter 2; Protein of unknown function; HVG1 has a paralog, VRG4, that arose from the whole genome duplication; Belongs to the TPT transporter family. SLC35D subfamily. | Putative uncharacterized transporter YOL162W; Putative protein of unknown function; member of the Dal5p subfamily of the major facilitator family. | 0.548 |
| PSA1 | HVG1 | YDL055C | YER039C | GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase); synthesizes GDP-mannose from GTP and mannose-1-phosphate in cell wall biosynthesis; required for normal cell wall structure. | Probable GDP-mannose transporter 2; Protein of unknown function; HVG1 has a paralog, VRG4, that arose from the whole genome duplication; Belongs to the TPT transporter family. SLC35D subfamily. | 0.611 |
