YER137C protein (Saccharomyces cerevisiae) - STRING interaction network

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YER137C

Uncharacterized protein YEL137C; Putative protein of unknown function. (148 aa)

Predicted Functional Partners:

YDL034W

0.832

GAL3

0.783

YBR062C

0.637

YER134C

0.597

YKR041W

0.492

LAM5

0.466

RPM2

0.464

TFC6

0.463

PDS5

0.457

ARI1

0.400

Your Current Organism:

Saccharomyces cerevisiae

NCBI taxonomy Id: 4932
Other names: ATCC 18824, Candida robusta, Mycoderma cerevisiae, NRRL Y-12632, S. cerevisiae, Saccharomyces capensis, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, yeast

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARI1	YER137C	YGL157W	YER137C	NADPH-dependent aldehyde reductase; utilizes aromatic and alophatic aldehyde substrates; member of the short-chain dehydrogenase/reductase superfamily.	Uncharacterized protein YEL137C; Putative protein of unknown function.	0.400
GAL3	YER137C	YDR009W	YER137C	Protein GAL3; Transcriptional regulator; involved in activation of the GAL genes in response to galactose; forms a complex with Gal80p to relieve Gal80p inhibition of Gal4p; binds galactose and ATP but does not have galactokinase activity; GAL3 has a paralog, GAL1, that arose from the whole genome duplication; Belongs to the GHMP kinase family. GalK subfamily.	Uncharacterized protein YEL137C; Putative protein of unknown function.	0.783
LAM5	YDL034W	YFL042C	YDL034W	Membrane-anchored lipid-binding protein LAM5; Putative sterol transfer protein; one of six StART-like domain-containing proteins in yeast that may be involved in sterol transfer between intracellular membranes; conserved across eukaryotes; has both GRAM and StART-like (VASt) domains; localizes to membrane contact sites throughout the cell, including nucleus-vacuole junctions and ER-mitochondrial contact sites.	Putative uncharacterized protein YDL034W; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps with verified gene GPR1/YDL035C; YDL034W is not an essential gene.	0.745
LAM5	YER137C	YFL042C	YER137C	Membrane-anchored lipid-binding protein LAM5; Putative sterol transfer protein; one of six StART-like domain-containing proteins in yeast that may be involved in sterol transfer between intracellular membranes; conserved across eukaryotes; has both GRAM and StART-like (VASt) domains; localizes to membrane contact sites throughout the cell, including nucleus-vacuole junctions and ER-mitochondrial contact sites.	Uncharacterized protein YEL137C; Putative protein of unknown function.	0.466
PDS5	YBR062C	YMR076C	YBR062C	Cohesion maintenance factor; involved in sister chromatid condensation and cohesion; colocalizes with cohesin on chromosomes; performs its cohesin maintenance function in pre-anaphase cells by protecting the integrity of the cohesion complex; also required during meiosis; relocalizes to the cytosol in response to hypoxia.	Uncharacterized RING finger protein YBR062C; Protein of unknown function that interacts with Msb2p; may play a role in activation of the filamentous growth pathway.	0.492
PDS5	YER137C	YMR076C	YER137C	Cohesion maintenance factor; involved in sister chromatid condensation and cohesion; colocalizes with cohesin on chromosomes; performs its cohesin maintenance function in pre-anaphase cells by protecting the integrity of the cohesion complex; also required during meiosis; relocalizes to the cytosol in response to hypoxia.	Uncharacterized protein YEL137C; Putative protein of unknown function.	0.457
RPM2	YER137C	YML091C	YER137C	Protein subunit of mitochondrial RNase P; has roles in nuclear transcription, cytoplasmic and mitochondrial RNA processing, and mitochondrial translation; distributed to mitochondria, cytoplasmic processing bodies, and the nucleus.	Uncharacterized protein YEL137C; Putative protein of unknown function.	0.464
TFC6	YER137C	YDR362C	YER137C	Subunit of RNA polymerase III transcription initiation factor complex; one of six subunits of RNA polymerase III transcription initiation factor complex (TFIIIC); part of TFIIIC TauB domain that binds BoxB promoter sites of tRNA and other genes; cooperates with Tfc3p in DNA binding; human homolog is TFIIIC-110.	Uncharacterized protein YEL137C; Putative protein of unknown function.	0.463
YBR062C	PDS5	YBR062C	YMR076C	Uncharacterized RING finger protein YBR062C; Protein of unknown function that interacts with Msb2p; may play a role in activation of the filamentous growth pathway.	Cohesion maintenance factor; involved in sister chromatid condensation and cohesion; colocalizes with cohesin on chromosomes; performs its cohesin maintenance function in pre-anaphase cells by protecting the integrity of the cohesion complex; also required during meiosis; relocalizes to the cytosol in response to hypoxia.	0.492
YBR062C	YER137C	YBR062C	YER137C	Uncharacterized RING finger protein YBR062C; Protein of unknown function that interacts with Msb2p; may play a role in activation of the filamentous growth pathway.	Uncharacterized protein YEL137C; Putative protein of unknown function.	0.637
YDL034W	LAM5	YDL034W	YFL042C	Putative uncharacterized protein YDL034W; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps with verified gene GPR1/YDL035C; YDL034W is not an essential gene.	Membrane-anchored lipid-binding protein LAM5; Putative sterol transfer protein; one of six StART-like domain-containing proteins in yeast that may be involved in sterol transfer between intracellular membranes; conserved across eukaryotes; has both GRAM and StART-like (VASt) domains; localizes to membrane contact sites throughout the cell, including nucleus-vacuole junctions and ER-mitochondrial contact sites.	0.745
YDL034W	YER137C	YDL034W	YER137C	Putative uncharacterized protein YDL034W; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps with verified gene GPR1/YDL035C; YDL034W is not an essential gene.	Uncharacterized protein YEL137C; Putative protein of unknown function.	0.832
YER134C	YER137C	YER134C	YER137C	Magnesium-dependent acid phosphatase; member of the haloacid dehalogenase superfamily; non-essential gene; Belongs to the HAD-like hydrolase superfamily.	Uncharacterized protein YEL137C; Putative protein of unknown function.	0.597
YER134C	YKR041W	YER134C	YKR041W	Magnesium-dependent acid phosphatase; member of the haloacid dehalogenase superfamily; non-essential gene; Belongs to the HAD-like hydrolase superfamily.	Uncharacterized protein YKR041W; Protein of unknown function; localizes to the mitotic spindle; overexpression of YKR041W affects endocytic protein trafficking.	0.449
YER137C	ARI1	YER137C	YGL157W	Uncharacterized protein YEL137C; Putative protein of unknown function.	NADPH-dependent aldehyde reductase; utilizes aromatic and alophatic aldehyde substrates; member of the short-chain dehydrogenase/reductase superfamily.	0.400
YER137C	GAL3	YER137C	YDR009W	Uncharacterized protein YEL137C; Putative protein of unknown function.	Protein GAL3; Transcriptional regulator; involved in activation of the GAL genes in response to galactose; forms a complex with Gal80p to relieve Gal80p inhibition of Gal4p; binds galactose and ATP but does not have galactokinase activity; GAL3 has a paralog, GAL1, that arose from the whole genome duplication; Belongs to the GHMP kinase family. GalK subfamily.	0.783
YER137C	LAM5	YER137C	YFL042C	Uncharacterized protein YEL137C; Putative protein of unknown function.	Membrane-anchored lipid-binding protein LAM5; Putative sterol transfer protein; one of six StART-like domain-containing proteins in yeast that may be involved in sterol transfer between intracellular membranes; conserved across eukaryotes; has both GRAM and StART-like (VASt) domains; localizes to membrane contact sites throughout the cell, including nucleus-vacuole junctions and ER-mitochondrial contact sites.	0.466
YER137C	PDS5	YER137C	YMR076C	Uncharacterized protein YEL137C; Putative protein of unknown function.	Cohesion maintenance factor; involved in sister chromatid condensation and cohesion; colocalizes with cohesin on chromosomes; performs its cohesin maintenance function in pre-anaphase cells by protecting the integrity of the cohesion complex; also required during meiosis; relocalizes to the cytosol in response to hypoxia.	0.457
YER137C	RPM2	YER137C	YML091C	Uncharacterized protein YEL137C; Putative protein of unknown function.	Protein subunit of mitochondrial RNase P; has roles in nuclear transcription, cytoplasmic and mitochondrial RNA processing, and mitochondrial translation; distributed to mitochondria, cytoplasmic processing bodies, and the nucleus.	0.464
YER137C	TFC6	YER137C	YDR362C	Uncharacterized protein YEL137C; Putative protein of unknown function.	Subunit of RNA polymerase III transcription initiation factor complex; one of six subunits of RNA polymerase III transcription initiation factor complex (TFIIIC); part of TFIIIC TauB domain that binds BoxB promoter sites of tRNA and other genes; cooperates with Tfc3p in DNA binding; human homolog is TFIIIC-110.	0.463

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