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YER158C protein (Saccharomyces cerevisiae) - STRING interaction network
"YER158C" - Protein of unknown function, has similarity to Afr1p in Saccharomyces cerevisiae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
YER158CProtein of unknown function, has similarity to Afr1p; potentially phosphorylated by Cdc28p (573 aa)    
Predicted Functional Partners:
YER156C
Putative protein of unknown function; interacts with Hsp82p and copurifies with Ipl1p; expression is copper responsive and downregulated in strains deleted for MAC1, a copper-responsive transcription factor; similarity to mammalian MYG1 (338 aa)
           
  0.731
YAL065C
Putative protein of unknown function; has homology to FLO1; possible pseudogene (128 aa)
           
  0.726
YBR062C
Protein of unknown function that interacts with Msb2p; may play a role in activation of the filamentous growth pathway (180 aa)
           
  0.626
SRL4
Protein of unknown function; involved in regulation of dNTP production; null mutant suppresses the lethality of lcd1 and rad53 mutations; expression is induced by Kar4p; May be involved in the regulation of dNTP production. Induces the SOS system when expressed in E.coli, therefore, it may play a role in DNA metabolism and/or in genome stability (281 aa)
           
  0.578
GEP5
Protein of unknown function, required for mitochondrial genome maintenance; detected in highly purified mitochondria in high-throughput studies; null mutant has decreased levels of cardiolipin and phosphatidylethanolamine; Essential for respiratory growth and required for maintenance of mtDNA. Required for cell survival in the absence of prohibitins (293 aa)
           
  0.578
APA1
Diadenosine 5’,5’’-P1,P4-tetraphosphate phosphorylase I (AP4A phosphorylase), involved in catabolism of bis(5’-nucleosidyl) tetraphosphates; has similarity to Apa2p; Ap4A phosphorylase catalyzes the phosphorolytic degradation of bis(5’-adenosyl) tetraphosphate (Ap4A) into ADP and ATP. Can also use other Np4N’ nucleotides (where N and N’ stand for A,C,G or U) as substrates with equal efficiency. Cannot catalyze the reverse reaction. Additionally, this enzyme can also catalyze the phosphorolytic degradation of adenosine 5’- phosphosulfate (AMPS) into ADP and sulfate, the reversible excha [...] (321 aa)
           
  0.509
PSF1
Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which is localized to DNA replication origins and implicated in assembly of the DNA replication machinery; Required for DNA replication. Functions as part of the GINS complex which plays an essential role in the initiation of DNA replication by binding to DNA replication origins and facilitating the assembly of the DNA replication machinery. Required for the chromatin binding of CDC45 (208 aa)
           
  0.482
MTC4
Protein of unknown function, required for normal growth rate at 15 degrees C; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; mtc4 is synthetically sick with cdc13-1 (694 aa)
           
  0.457
GLC7
Type 1 serine/threonine protein phosphatase catalytic subunit, involved in many processes (eg- glycogen metabolism, sporulation, mitosis); accumulates at mating projections by interaction with Afr1p; interacts with many regulatory subunits; Involved in control of glycogen metabolism, meiosis, translation, chromosome segregation, cell polarity and G2/M cell cycle progression. PP1 may act in opposition to the IPL1 protein kinase in regulating chromosome segregation by dephosphorylating H3S10ph. The BUD14-GLC7 complex is necessary to regulate microtubule dynamics at the cortex and may fun [...] (312 aa)
       
 
  0.442
PAA1
Polyamine acetyltransferase; acetylates polyamines (e.g. putrescine, spermidine, spermine) and also aralkylamines (e.g. tryptamine, phenylethylamine); may be involved in transcription and/or DNA replication; Acetylates spermine and probably also other polyamines such as putrescine or spermidine. May regulate the levels of polyamines on chromosomal DNA, which would modify chromatin structure and affect transcription or replication. Also able to acetylate arylalkylamines such as tryptamine and serotonin in vitro (191 aa)
           
  0.418
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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