| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CDC13 | YER186C | YDL220C | YER186C | Cell division control protein 13; Single stranded DNA-binding protein found at TG1-3 telomere G-tails; key roles in regulation of telomerase, telomere end protection, conventional telomere replication; regulates telomere replication through recruitment of specific sub-complexes, essential function is telomere capping; forms homodimer via N-terminus; disruption of dimerization leads to short telomeres; autophagy and proteasome are involved in Cdc13p degradation; differentially phosphorylated through cell cycle. | Uncharacterized protein YER186C; Putative protein of unknown function. | 0.450 |
| GMC2 | YER186C | YLR445W | YER186C | Grand meiotic recombination cluster protein 2; Protein involved in meiotic crossing over; component of the Synaptonemal Complex (SC) along with Ecm11p; required for the efficient loading of the SC transverse filament protein, Zip1p; promotes SUMOylation of Ecm11p; mutants are delayed in meiotic nuclear division and are defective in synaptonemal complex assembly; transcription is regulated by Ume6p and induced in response to alpha factor. | Uncharacterized protein YER186C; Putative protein of unknown function. | 0.414 |
| GRX8 | JLP1 | YLR364W | YLL057C | Glutaredoxin-8; Glutaredoxin that employs a dithiol mechanism of catalysis; monomeric; activity is low and null mutation does not affect sensitivity to oxidative stress; GFP-fusion protein localizes to the cytoplasm; expression strongly induced by arsenic. | Fe(II)-dependent sulfonate/alpha-ketoglutarate dioxygenase; involved in sulfonate catabolism for use as a sulfur source; contains sequence that resembles a J domain (typified by the E. coli DnaJ protein); induced by sulphur starvation. | 0.712 |
| GRX8 | YBR191W-A | YLR364W | YBR191W-A | Glutaredoxin-8; Glutaredoxin that employs a dithiol mechanism of catalysis; monomeric; activity is low and null mutation does not affect sensitivity to oxidative stress; GFP-fusion protein localizes to the cytoplasm; expression strongly induced by arsenic. | Putative uncharacterized protein YBR191W-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | 0.478 |
| GRX8 | YER186C | YLR364W | YER186C | Glutaredoxin-8; Glutaredoxin that employs a dithiol mechanism of catalysis; monomeric; activity is low and null mutation does not affect sensitivity to oxidative stress; GFP-fusion protein localizes to the cytoplasm; expression strongly induced by arsenic. | Uncharacterized protein YER186C; Putative protein of unknown function. | 0.471 |
| GRX8 | YIL166C | YLR364W | YIL166C | Glutaredoxin-8; Glutaredoxin that employs a dithiol mechanism of catalysis; monomeric; activity is low and null mutation does not affect sensitivity to oxidative stress; GFP-fusion protein localizes to the cytoplasm; expression strongly induced by arsenic. | Uncharacterized transporter YIL166C; Putative protein with similarity to allantoate permease; similar to the allantoate permease (Dal5p) subfamily of the major facilitator superfamily; mRNA expression is elevated by sulfur limitation; YIL166C is a non-essential gene. | 0.705 |
| JLP1 | GRX8 | YLL057C | YLR364W | Fe(II)-dependent sulfonate/alpha-ketoglutarate dioxygenase; involved in sulfonate catabolism for use as a sulfur source; contains sequence that resembles a J domain (typified by the E. coli DnaJ protein); induced by sulphur starvation. | Glutaredoxin-8; Glutaredoxin that employs a dithiol mechanism of catalysis; monomeric; activity is low and null mutation does not affect sensitivity to oxidative stress; GFP-fusion protein localizes to the cytoplasm; expression strongly induced by arsenic. | 0.712 |
| JLP1 | YBR191W-A | YLL057C | YBR191W-A | Fe(II)-dependent sulfonate/alpha-ketoglutarate dioxygenase; involved in sulfonate catabolism for use as a sulfur source; contains sequence that resembles a J domain (typified by the E. coli DnaJ protein); induced by sulphur starvation. | Putative uncharacterized protein YBR191W-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | 0.539 |
| JLP1 | YER186C | YLL057C | YER186C | Fe(II)-dependent sulfonate/alpha-ketoglutarate dioxygenase; involved in sulfonate catabolism for use as a sulfur source; contains sequence that resembles a J domain (typified by the E. coli DnaJ protein); induced by sulphur starvation. | Uncharacterized protein YER186C; Putative protein of unknown function. | 0.447 |
| JLP1 | YIL166C | YLL057C | YIL166C | Fe(II)-dependent sulfonate/alpha-ketoglutarate dioxygenase; involved in sulfonate catabolism for use as a sulfur source; contains sequence that resembles a J domain (typified by the E. coli DnaJ protein); induced by sulphur starvation. | Uncharacterized transporter YIL166C; Putative protein with similarity to allantoate permease; similar to the allantoate permease (Dal5p) subfamily of the major facilitator superfamily; mRNA expression is elevated by sulfur limitation; YIL166C is a non-essential gene. | 0.882 |
| PUG1 | YER186C | YER185W | YER186C | Protoporphyrin uptake protein 1; Plasma membrane protein involved in protoprophyrin and heme transport; roles in the uptake of protoprophyrin IX and the efflux of heme; expression is induced under both low-heme and low-oxygen conditions; member of the fungal lipid-translocating exporter (LTE) family of proteins. | Uncharacterized protein YER186C; Putative protein of unknown function. | 0.564 |
| YBR191W-A | GRX8 | YBR191W-A | YLR364W | Putative uncharacterized protein YBR191W-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | Glutaredoxin-8; Glutaredoxin that employs a dithiol mechanism of catalysis; monomeric; activity is low and null mutation does not affect sensitivity to oxidative stress; GFP-fusion protein localizes to the cytoplasm; expression strongly induced by arsenic. | 0.478 |
| YBR191W-A | JLP1 | YBR191W-A | YLL057C | Putative uncharacterized protein YBR191W-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | Fe(II)-dependent sulfonate/alpha-ketoglutarate dioxygenase; involved in sulfonate catabolism for use as a sulfur source; contains sequence that resembles a J domain (typified by the E. coli DnaJ protein); induced by sulphur starvation. | 0.539 |
| YBR191W-A | YER186C | YBR191W-A | YER186C | Putative uncharacterized protein YBR191W-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | Uncharacterized protein YER186C; Putative protein of unknown function. | 0.640 |
| YBR191W-A | YIL166C | YBR191W-A | YIL166C | Putative uncharacterized protein YBR191W-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | Uncharacterized transporter YIL166C; Putative protein with similarity to allantoate permease; similar to the allantoate permease (Dal5p) subfamily of the major facilitator superfamily; mRNA expression is elevated by sulfur limitation; YIL166C is a non-essential gene. | 0.510 |
| YER186C | CDC13 | YER186C | YDL220C | Uncharacterized protein YER186C; Putative protein of unknown function. | Cell division control protein 13; Single stranded DNA-binding protein found at TG1-3 telomere G-tails; key roles in regulation of telomerase, telomere end protection, conventional telomere replication; regulates telomere replication through recruitment of specific sub-complexes, essential function is telomere capping; forms homodimer via N-terminus; disruption of dimerization leads to short telomeres; autophagy and proteasome are involved in Cdc13p degradation; differentially phosphorylated through cell cycle. | 0.450 |
| YER186C | GMC2 | YER186C | YLR445W | Uncharacterized protein YER186C; Putative protein of unknown function. | Grand meiotic recombination cluster protein 2; Protein involved in meiotic crossing over; component of the Synaptonemal Complex (SC) along with Ecm11p; required for the efficient loading of the SC transverse filament protein, Zip1p; promotes SUMOylation of Ecm11p; mutants are delayed in meiotic nuclear division and are defective in synaptonemal complex assembly; transcription is regulated by Ume6p and induced in response to alpha factor. | 0.414 |
| YER186C | GRX8 | YER186C | YLR364W | Uncharacterized protein YER186C; Putative protein of unknown function. | Glutaredoxin-8; Glutaredoxin that employs a dithiol mechanism of catalysis; monomeric; activity is low and null mutation does not affect sensitivity to oxidative stress; GFP-fusion protein localizes to the cytoplasm; expression strongly induced by arsenic. | 0.471 |
| YER186C | JLP1 | YER186C | YLL057C | Uncharacterized protein YER186C; Putative protein of unknown function. | Fe(II)-dependent sulfonate/alpha-ketoglutarate dioxygenase; involved in sulfonate catabolism for use as a sulfur source; contains sequence that resembles a J domain (typified by the E. coli DnaJ protein); induced by sulphur starvation. | 0.447 |
| YER186C | PUG1 | YER186C | YER185W | Uncharacterized protein YER186C; Putative protein of unknown function. | Protoporphyrin uptake protein 1; Plasma membrane protein involved in protoprophyrin and heme transport; roles in the uptake of protoprophyrin IX and the efflux of heme; expression is induced under both low-heme and low-oxygen conditions; member of the fungal lipid-translocating exporter (LTE) family of proteins. | 0.564 |