node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ECM8 | GIP1 | YBR076W | YBR045C | Non-essential protein of unknown function. | GLC7-interacting protein 1; Meiosis-specific regulatory subunit of the Glc7p protein phosphatase; regulates spore wall formation and septin organization, required for expression of some late meiotic genes and for normal localization of Glc7p. | 0.435 |
ECM8 | SPO20 | YBR076W | YMR017W | Non-essential protein of unknown function. | Sporulation-specific protein 20; Meiosis-specific subunit of the t-SNARE complex; required for prospore membrane formation during sporulation; similar to but not functionally redundant with Sec9p; binds to phosphatidic acid; SNAP-25 homolog. | 0.473 |
ECM8 | SPS1 | YBR076W | YDR523C | Non-essential protein of unknown function. | Sporulation-specific protein 1; Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis. | 0.499 |
ECM8 | YFL012W | YBR076W | YFL012W | Non-essential protein of unknown function. | Uncharacterized protein YFL012W; Putative protein of unknown function; transcribed during sporulation; null mutant exhibits increased resistance to rapamycin. | 0.727 |
GIP1 | ECM8 | YBR045C | YBR076W | GLC7-interacting protein 1; Meiosis-specific regulatory subunit of the Glc7p protein phosphatase; regulates spore wall formation and septin organization, required for expression of some late meiotic genes and for normal localization of Glc7p. | Non-essential protein of unknown function. | 0.435 |
GIP1 | SPO20 | YBR045C | YMR017W | GLC7-interacting protein 1; Meiosis-specific regulatory subunit of the Glc7p protein phosphatase; regulates spore wall formation and septin organization, required for expression of some late meiotic genes and for normal localization of Glc7p. | Sporulation-specific protein 20; Meiosis-specific subunit of the t-SNARE complex; required for prospore membrane formation during sporulation; similar to but not functionally redundant with Sec9p; binds to phosphatidic acid; SNAP-25 homolog. | 0.733 |
GIP1 | SPS1 | YBR045C | YDR523C | GLC7-interacting protein 1; Meiosis-specific regulatory subunit of the Glc7p protein phosphatase; regulates spore wall formation and septin organization, required for expression of some late meiotic genes and for normal localization of Glc7p. | Sporulation-specific protein 1; Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis. | 0.548 |
GIP1 | YFL012W | YBR045C | YFL012W | GLC7-interacting protein 1; Meiosis-specific regulatory subunit of the Glc7p protein phosphatase; regulates spore wall formation and septin organization, required for expression of some late meiotic genes and for normal localization of Glc7p. | Uncharacterized protein YFL012W; Putative protein of unknown function; transcribed during sporulation; null mutant exhibits increased resistance to rapamycin. | 0.605 |
HXT14 | SPS1 | YNL318C | YDR523C | Protein with similarity to hexose transporter family members; expression is induced in low glucose and repressed in high glucose; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. | Sporulation-specific protein 1; Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis. | 0.464 |
HXT14 | YFL012W | YNL318C | YFL012W | Protein with similarity to hexose transporter family members; expression is induced in low glucose and repressed in high glucose; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. | Uncharacterized protein YFL012W; Putative protein of unknown function; transcribed during sporulation; null mutant exhibits increased resistance to rapamycin. | 0.528 |
RRT5 | SNZ3 | YFR032C | YFL059W | Regulator of rDNA transcription protein 5; Putative protein of unknown function; non-essential gene identified in a screen for mutants with increased levels of rDNA transcription; expressed at high levels during sporulation. | Probable pyridoxal 5'-phosphate synthase subunit SNZ3; Member of a stationary phase-induced gene family; expressed in the presence of galactose; transcription of SNZ3 is induced prior to diauxic shift, and also in the absence of thiamin in a Thi2p-dependent manner; forms a coregulated gene pair with SNO3. | 0.517 |
RRT5 | WWM1 | YFR032C | YFL010C | Regulator of rDNA transcription protein 5; Putative protein of unknown function; non-essential gene identified in a screen for mutants with increased levels of rDNA transcription; expressed at high levels during sporulation. | WW domain containing protein of unknown function; binds to Mca1p, a caspase-related protease that regulates H2O2-induced apoptosis; overexpression causes G1 phase growth arrest and clonal death that is suppressed by overexpression of MCA1. | 0.567 |
RRT5 | YFL012W | YFR032C | YFL012W | Regulator of rDNA transcription protein 5; Putative protein of unknown function; non-essential gene identified in a screen for mutants with increased levels of rDNA transcription; expressed at high levels during sporulation. | Uncharacterized protein YFL012W; Putative protein of unknown function; transcribed during sporulation; null mutant exhibits increased resistance to rapamycin. | 0.835 |
RRT5 | YFR006W | YFR032C | YFR006W | Regulator of rDNA transcription protein 5; Putative protein of unknown function; non-essential gene identified in a screen for mutants with increased levels of rDNA transcription; expressed at high levels during sporulation. | Uncharacterized peptidase YFR006W; Putative X-Pro aminopeptidase; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YFR006W is not an essential gene. | 0.697 |
SNZ3 | RRT5 | YFL059W | YFR032C | Probable pyridoxal 5'-phosphate synthase subunit SNZ3; Member of a stationary phase-induced gene family; expressed in the presence of galactose; transcription of SNZ3 is induced prior to diauxic shift, and also in the absence of thiamin in a Thi2p-dependent manner; forms a coregulated gene pair with SNO3. | Regulator of rDNA transcription protein 5; Putative protein of unknown function; non-essential gene identified in a screen for mutants with increased levels of rDNA transcription; expressed at high levels during sporulation. | 0.517 |
SNZ3 | YFL012W | YFL059W | YFL012W | Probable pyridoxal 5'-phosphate synthase subunit SNZ3; Member of a stationary phase-induced gene family; expressed in the presence of galactose; transcription of SNZ3 is induced prior to diauxic shift, and also in the absence of thiamin in a Thi2p-dependent manner; forms a coregulated gene pair with SNO3. | Uncharacterized protein YFL012W; Putative protein of unknown function; transcribed during sporulation; null mutant exhibits increased resistance to rapamycin. | 0.545 |
SNZ3 | YFR006W | YFL059W | YFR006W | Probable pyridoxal 5'-phosphate synthase subunit SNZ3; Member of a stationary phase-induced gene family; expressed in the presence of galactose; transcription of SNZ3 is induced prior to diauxic shift, and also in the absence of thiamin in a Thi2p-dependent manner; forms a coregulated gene pair with SNO3. | Uncharacterized peptidase YFR006W; Putative X-Pro aminopeptidase; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YFR006W is not an essential gene. | 0.446 |
SPO20 | ECM8 | YMR017W | YBR076W | Sporulation-specific protein 20; Meiosis-specific subunit of the t-SNARE complex; required for prospore membrane formation during sporulation; similar to but not functionally redundant with Sec9p; binds to phosphatidic acid; SNAP-25 homolog. | Non-essential protein of unknown function. | 0.473 |
SPO20 | GIP1 | YMR017W | YBR045C | Sporulation-specific protein 20; Meiosis-specific subunit of the t-SNARE complex; required for prospore membrane formation during sporulation; similar to but not functionally redundant with Sec9p; binds to phosphatidic acid; SNAP-25 homolog. | GLC7-interacting protein 1; Meiosis-specific regulatory subunit of the Glc7p protein phosphatase; regulates spore wall formation and septin organization, required for expression of some late meiotic genes and for normal localization of Glc7p. | 0.733 |
SPO20 | SPS1 | YMR017W | YDR523C | Sporulation-specific protein 20; Meiosis-specific subunit of the t-SNARE complex; required for prospore membrane formation during sporulation; similar to but not functionally redundant with Sec9p; binds to phosphatidic acid; SNAP-25 homolog. | Sporulation-specific protein 1; Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis. | 0.591 |