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ALR2 protein (Saccharomyces cerevisiae) - STRING interaction network
"ALR2" - Probable Mg(2+) transporter in Saccharomyces cerevisiae
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
ALR2Probable Mg(2+) transporter; overexpression confers increased tolerance to Al(3+) and Ga(3+) ions; plays a role in regulating Ty1 transposition; Plasma membrane magnesium transporter (858 aa)    
Predicted Functional Partners:
RRT5
Putative protein of unknown function; non-essential gene identified in a screen for mutants with increased levels of rDNA transcription; expressed at high levels during sporulation; May be involved in the modulation of rDNA transcription (289 aa)
           
  0.697
MNR2
Vacuolar membrane protein required for magnesium homeostasis; putative magnesium transporter; has similarity to Alr1p and Alr2p, which mediate influx of Mg2+ and other divalent cations (969 aa)
       
 
0.643
YGR073C
Dubious open reading frame unlikely to encode a functional protein, extensively overlaps essential SMD1 gene encoding a U6 snRNP protein (123 aa)
           
  0.639
AIM19
Protein of unknown function; mitochondrial protein that physically interacts with Tim23p; null mutant displays reduced respiratory growth (157 aa)
           
  0.627
YNL046W
Putative protein of unknown function; expression depends on Swi5p; GFP-fusion protein localizes to the endoplasmic reticulum; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO) (172 aa)
           
  0.572
TRM13
2’-O-methyltransferase responsible for modification of tRNA at position 4; C-terminal domain has similarity to Rossmann-fold (RFM) superfamily of RNA methyltransferases; tRNA methylase which 2’-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His) (476 aa)
           
  0.540
YFL065C
Putative protein of unknown function; induced by treatment with 8-methoxypsoralen and UVA irradiation (102 aa)
           
  0.540
ALR1
Plasma membrane Mg(2+) transporter, expression and turnover are regulated by Mg(2+) concentration; overexpression confers increased tolerance to Al(3+) and Ga(3+) ions; Plasma membrane magnesium transporter (859 aa)
       
 
0.534
MRS2
Mitochondrial inner membrane Mg(2+) channel, required for maintenance of intramitochondrial Mg(2+) concentrations at the correct level to support splicing of group II introns; High-conductance magnesium-selective channel that mediates the influx of magnesium into the mitochondrial matrix (PubMed-12628916, PubMed-17827224, PubMed-20653776, PubMed-23999289). Essential for the splicing of mRNA group II introns in mitochondria by affecting mitochondrial magnesium concentrations, which are critical for group II intron splicing. It also suppresses a variety of mitochondrial intron mutations [...] (470 aa)
           
  0.525
YFL066C
Helicase-like protein encoded within the telomeric Y’ element; induced by treatment with 8-methoxypsoralen and UVA irradiation; Catalyzes DNA unwinding and is involved in telomerase- independent telomere maintenance (392 aa)
         
  0.519
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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