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BRP1 protein (Saccharomyces cerevisiae) - STRING interaction network
"BRP1" - Dubious ORF located in the upstream region of PMA1, deletion leads to polyamine resistance due to downregulation of PMA1 in Saccharomyces cerevisiae
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second shell of interactors
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proteins of unknown 3D structure
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co-expression
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BRP1Dubious ORF located in the upstream region of PMA1, deletion leads to polyamine resistance due to downregulation of PMA1 (125 aa)    
Predicted Functional Partners:
YNL198C
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data (100 aa)
           
  0.677
YPL062W
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YPL062W is not an essential gene; homozygous diploid mutant shows a decrease in glycogen accumulation (134 aa)
     
   
  0.600
SKY1
SR protein kinase (SRPK) involved in regulating proteins involved in mRNA metabolism and cation homeostasis; similar to human SRPK1; Constitutively active kinase, specifically and sequentially phosphorylates serine/arginine (SR)-type shuttling mRNA binding proteins in their RS dipeptide repeats (742 aa)
           
  0.483
YIL089W
Protein of unknown function found in the ER and vacuole lumen; overexpression of YIL089W affects endocytic protein trafficking (205 aa)
           
  0.481
YOL050C
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps verified gene GAL11; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO) (106 aa)
           
  0.480
PMA1
Plasma membrane H+-ATPase, pumps protons out of the cell; major regulator of cytoplasmic pH and plasma membrane potential; P2-type ATPase; Hsp30p plays a role in Pma1p regulation; interactions with Std1p appear to propagate [GAR+]; The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses (918 aa)
           
  0.450
YOR022C
Protein with similarity to bovine phospholipase A1; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Probable phospholipase that hydrolyzes phosphatidic acid (715 aa)
           
  0.449
PTK2
Putative serine/threonine protein kinase involved in regulation of ion transport across plasma membrane; enhances spermine uptake; Essential determinant for high-affinity spermidine transport. Required for the activation of the plasma membrane proton pump PMA1 via phosphorylation of ’Ser-899’ (818 aa)
           
  0.448
RRG9
Protein of unknown function; null mutant lacks mitochondrial DNA and cannot grow on glycerol; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Required for respiratory activity and maintenance and expression of the mitochondrial genome (214 aa)
           
  0.445
FYV5
Protein involved in regulation of the mating pathway; binds with Matalpha2p to promoters of haploid-specific genes; required for survival upon exposure to K1 killer toxin; involved in ion homeostasis; Involved in maintaining an adequate ionic strength homeostasis of the cellular aqueous environment, necessary for normal growth rate. Required for survival upon exposure to K1 killer toxin and hence plays a role in cell wall glucan synthesis. Required for dithiothreitol (DTT) resistance. Involved in cell cycle progression (152 aa)
           
  0.440
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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