node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CDC27 | YGL034C | YBL084C | YGL034C | Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C); APC/C is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition. | Uncharacterized protein YGL034C; Putative protein of unknown function; conserved among S. cerevisiae strains; YGL034C is not an essential gene. | 0.544 |
JSN1 | PUF2 | YJR091C | YPR042C | Protein JSN1; Member of the Puf family of RNA-binding proteins; interacts with mRNAs encoding membrane-associated proteins; involved in localizing the Arp2/3 complex to mitochondria; overexpression causes increased sensitivity to benomyl; JSN1 has a paralog, PUF2, that arose from the whole genome duplication. | PUF family mRNA-binding protein; Pumilio homology domain confers RNA binding activity; preferentially binds mRNAs encoding membrane-associated proteins; binding site composed of two UAAU tetranucleotides, separated by a 3-nt linker; PUF2 has a paralog, JSN1, that arose from the whole genome duplication. | 0.572 |
JSN1 | YGL034C | YJR091C | YGL034C | Protein JSN1; Member of the Puf family of RNA-binding proteins; interacts with mRNAs encoding membrane-associated proteins; involved in localizing the Arp2/3 complex to mitochondria; overexpression causes increased sensitivity to benomyl; JSN1 has a paralog, PUF2, that arose from the whole genome duplication. | Uncharacterized protein YGL034C; Putative protein of unknown function; conserved among S. cerevisiae strains; YGL034C is not an essential gene. | 0.607 |
NOP1 | YGL034C | YDL014W | YGL034C | rRNA 2'-O-methyltransferase fibrillarin; Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus; component of the small subunit processome complex, which is required for processing of pre-18S rRNA; ortholog of mammalian fibrillarin; inviability of the null mutant is functionally complemented by human FBL. | Uncharacterized protein YGL034C; Putative protein of unknown function; conserved among S. cerevisiae strains; YGL034C is not an essential gene. | 0.442 |
PUF2 | JSN1 | YPR042C | YJR091C | PUF family mRNA-binding protein; Pumilio homology domain confers RNA binding activity; preferentially binds mRNAs encoding membrane-associated proteins; binding site composed of two UAAU tetranucleotides, separated by a 3-nt linker; PUF2 has a paralog, JSN1, that arose from the whole genome duplication. | Protein JSN1; Member of the Puf family of RNA-binding proteins; interacts with mRNAs encoding membrane-associated proteins; involved in localizing the Arp2/3 complex to mitochondria; overexpression causes increased sensitivity to benomyl; JSN1 has a paralog, PUF2, that arose from the whole genome duplication. | 0.572 |
PUF2 | YGL034C | YPR042C | YGL034C | PUF family mRNA-binding protein; Pumilio homology domain confers RNA binding activity; preferentially binds mRNAs encoding membrane-associated proteins; binding site composed of two UAAU tetranucleotides, separated by a 3-nt linker; PUF2 has a paralog, JSN1, that arose from the whole genome duplication. | Uncharacterized protein YGL034C; Putative protein of unknown function; conserved among S. cerevisiae strains; YGL034C is not an essential gene. | 0.610 |
SSN2 | YGL034C | YDR443C | YGL034C | Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; required for stable association of Srb10p-Srb11p kinase; essential for transcriptional regulation. | Uncharacterized protein YGL034C; Putative protein of unknown function; conserved among S. cerevisiae strains; YGL034C is not an essential gene. | 0.598 |
YCR085W | YGL034C | YCR085W | YGL034C | Uncharacterized protein YCR085W; Putative protein of unknown function; conserved among S. cerevisiae strains; YCR085W is not an essential gene. | Uncharacterized protein YGL034C; Putative protein of unknown function; conserved among S. cerevisiae strains; YGL034C is not an essential gene. | 0.412 |
YGL034C | CDC27 | YGL034C | YBL084C | Uncharacterized protein YGL034C; Putative protein of unknown function; conserved among S. cerevisiae strains; YGL034C is not an essential gene. | Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C); APC/C is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition. | 0.544 |
YGL034C | JSN1 | YGL034C | YJR091C | Uncharacterized protein YGL034C; Putative protein of unknown function; conserved among S. cerevisiae strains; YGL034C is not an essential gene. | Protein JSN1; Member of the Puf family of RNA-binding proteins; interacts with mRNAs encoding membrane-associated proteins; involved in localizing the Arp2/3 complex to mitochondria; overexpression causes increased sensitivity to benomyl; JSN1 has a paralog, PUF2, that arose from the whole genome duplication. | 0.607 |
YGL034C | NOP1 | YGL034C | YDL014W | Uncharacterized protein YGL034C; Putative protein of unknown function; conserved among S. cerevisiae strains; YGL034C is not an essential gene. | rRNA 2'-O-methyltransferase fibrillarin; Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus; component of the small subunit processome complex, which is required for processing of pre-18S rRNA; ortholog of mammalian fibrillarin; inviability of the null mutant is functionally complemented by human FBL. | 0.442 |
YGL034C | PUF2 | YGL034C | YPR042C | Uncharacterized protein YGL034C; Putative protein of unknown function; conserved among S. cerevisiae strains; YGL034C is not an essential gene. | PUF family mRNA-binding protein; Pumilio homology domain confers RNA binding activity; preferentially binds mRNAs encoding membrane-associated proteins; binding site composed of two UAAU tetranucleotides, separated by a 3-nt linker; PUF2 has a paralog, JSN1, that arose from the whole genome duplication. | 0.610 |
YGL034C | SSN2 | YGL034C | YDR443C | Uncharacterized protein YGL034C; Putative protein of unknown function; conserved among S. cerevisiae strains; YGL034C is not an essential gene. | Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; required for stable association of Srb10p-Srb11p kinase; essential for transcriptional regulation. | 0.598 |
YGL034C | YCR085W | YGL034C | YCR085W | Uncharacterized protein YGL034C; Putative protein of unknown function; conserved among S. cerevisiae strains; YGL034C is not an essential gene. | Uncharacterized protein YCR085W; Putative protein of unknown function; conserved among S. cerevisiae strains; YCR085W is not an essential gene. | 0.412 |