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CUE3 protein (Saccharomyces cerevisiae) - STRING interaction network
"CUE3" - Protein of unknown function in Saccharomyces cerevisiae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CUE3Protein of unknown function; has a CUE domain that binds ubiquitin, which may facilitate intramolecular monoubiquitination (624 aa)    
Predicted Functional Partners:
UBI4
Ubiquitin, becomes conjugated to proteins, marking them for selective degradation via the ubiquitin-26S proteasome system; essential for the cellular stress response; encoded as a polyubiquitin precursor comprised of 5 head-to-tail repeats; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiqui [...] (381 aa)
       
 
  0.606
YNL011C
Putative protein of unknown function; YNL011C is not an essential gene (444 aa)
           
  0.518
YMR187C
Putative protein of unknown function; YMR187C is not an essential gene (431 aa)
           
  0.518
YGR149W
Putative protein of unknown function; predicted to be an integal membrane protein (432 aa)
           
  0.518
YGL101W
Putative protein of unknown function; non-essential gene with similarity to YBR242W; interacts with the DNA helicase Hpr5p (215 aa)
           
  0.485
CUE4
Protein of unknown function; has a CUE domain that binds ubiquitin, which may facilitate intramolecular monoubiquitination (117 aa)
           
  0.481
YJL007C
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data (104 aa)
           
  0.446
YMR052C-A
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data (121 aa)
           
  0.416
TMA7
Protein of unknown that associates with ribosomes; null mutant exhibits translation defects, altered polyribosome profiles, and resistance to the translation inhibitor anisomcyin; Involved in protein synthesis (64 aa)
           
  0.410
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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