| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AQY1 | BOR1 | YPR192W | YNL275W | Aquaporin-1; Spore-specific water channel; mediates the transport of water across cell membranes, developmentally controlled; may play a role in spore maturation, probably by allowing water outflow, may be involved in freeze tolerance. | Boron efflux transporter of the plasma membrane; binds HCO3-, I-, Br-, NO3- and Cl-; has similarity to the characterized boron efflux transporter A. thaliana BOR1. | 0.473 |
| AQY1 | OPT2 | YPR192W | YPR194C | Aquaporin-1; Spore-specific water channel; mediates the transport of water across cell membranes, developmentally controlled; may play a role in spore maturation, probably by allowing water outflow, may be involved in freeze tolerance. | Oligopeptide transporter; localized to peroxisomes and affects glutathione redox homeostasis; also localizes to the plasma membrane (PM) and to the late Golgi, and has a role in maintenance of lipid asymmetry between the inner and outer leaflets of the PM; member of the OPT family, with potential orthologs in S. pombe and C. albicans; also plays a role in formation of mature vacuoles and in polarized cell growth. | 0.487 |
| AQY1 | YGL114W | YPR192W | YGL114W | Aquaporin-1; Spore-specific water channel; mediates the transport of water across cell membranes, developmentally controlled; may play a role in spore maturation, probably by allowing water outflow, may be involved in freeze tolerance. | Putative protein of unknown function; predicted member of the oligopeptide transporter (OPT) family of membrane transporters. | 0.527 |
| AQY2 | BOR1 | YLL052C | YNL275W | Aquaporin-like protein 2; Water channel that mediates water transport across cell membranes; only expressed in proliferating cells; controlled by osmotic signals; may be involved in freeze tolerance; disrupted by a stop codon in many S. cerevisiae strains; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Boron efflux transporter of the plasma membrane; binds HCO3-, I-, Br-, NO3- and Cl-; has similarity to the characterized boron efflux transporter A. thaliana BOR1. | 0.471 |
| AQY2 | YGL114W | YLL052C | YGL114W | Aquaporin-like protein 2; Water channel that mediates water transport across cell membranes; only expressed in proliferating cells; controlled by osmotic signals; may be involved in freeze tolerance; disrupted by a stop codon in many S. cerevisiae strains; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Putative protein of unknown function; predicted member of the oligopeptide transporter (OPT) family of membrane transporters. | 0.529 |
| ATR1 | YGL114W | YML116W | YGL114W | Aminotriazole resistance protein; Multidrug efflux pump of the major facilitator superfamily; required for resistance to aminotriazole and 4-nitroquinoline-N-oxide; ATR1 has a paralog, YMR279C, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress. | Putative protein of unknown function; predicted member of the oligopeptide transporter (OPT) family of membrane transporters. | 0.492 |
| BOR1 | AQY1 | YNL275W | YPR192W | Boron efflux transporter of the plasma membrane; binds HCO3-, I-, Br-, NO3- and Cl-; has similarity to the characterized boron efflux transporter A. thaliana BOR1. | Aquaporin-1; Spore-specific water channel; mediates the transport of water across cell membranes, developmentally controlled; may play a role in spore maturation, probably by allowing water outflow, may be involved in freeze tolerance. | 0.473 |
| BOR1 | AQY2 | YNL275W | YLL052C | Boron efflux transporter of the plasma membrane; binds HCO3-, I-, Br-, NO3- and Cl-; has similarity to the characterized boron efflux transporter A. thaliana BOR1. | Aquaporin-like protein 2; Water channel that mediates water transport across cell membranes; only expressed in proliferating cells; controlled by osmotic signals; may be involved in freeze tolerance; disrupted by a stop codon in many S. cerevisiae strains; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.471 |
| BOR1 | PCA1 | YNL275W | YBR295W | Boron efflux transporter of the plasma membrane; binds HCO3-, I-, Br-, NO3- and Cl-; has similarity to the characterized boron efflux transporter A. thaliana BOR1. | Cadmium transporting P-type ATPase; may also have a role in copper and iron homeostasis; stabilized by Cd binding, which prevents ubiquitination; S288C and other lab strains contain a G970R mutation which eliminates Cd transport function; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily. | 0.472 |
| BOR1 | YGL114W | YNL275W | YGL114W | Boron efflux transporter of the plasma membrane; binds HCO3-, I-, Br-, NO3- and Cl-; has similarity to the characterized boron efflux transporter A. thaliana BOR1. | Putative protein of unknown function; predicted member of the oligopeptide transporter (OPT) family of membrane transporters. | 0.593 |
| OPT1 | YGL114W | YJL212C | YGL114W | Proton-coupled oligopeptide transporter of the plasma membrane; also transports glutathione and phytochelatin; member of the OPT family. | Putative protein of unknown function; predicted member of the oligopeptide transporter (OPT) family of membrane transporters. | 0.625 |
| OPT2 | AQY1 | YPR194C | YPR192W | Oligopeptide transporter; localized to peroxisomes and affects glutathione redox homeostasis; also localizes to the plasma membrane (PM) and to the late Golgi, and has a role in maintenance of lipid asymmetry between the inner and outer leaflets of the PM; member of the OPT family, with potential orthologs in S. pombe and C. albicans; also plays a role in formation of mature vacuoles and in polarized cell growth. | Aquaporin-1; Spore-specific water channel; mediates the transport of water across cell membranes, developmentally controlled; may play a role in spore maturation, probably by allowing water outflow, may be involved in freeze tolerance. | 0.487 |
| OPT2 | YGL114W | YPR194C | YGL114W | Oligopeptide transporter; localized to peroxisomes and affects glutathione redox homeostasis; also localizes to the plasma membrane (PM) and to the late Golgi, and has a role in maintenance of lipid asymmetry between the inner and outer leaflets of the PM; member of the OPT family, with potential orthologs in S. pombe and C. albicans; also plays a role in formation of mature vacuoles and in polarized cell growth. | Putative protein of unknown function; predicted member of the oligopeptide transporter (OPT) family of membrane transporters. | 0.470 |
| PCA1 | BOR1 | YBR295W | YNL275W | Cadmium transporting P-type ATPase; may also have a role in copper and iron homeostasis; stabilized by Cd binding, which prevents ubiquitination; S288C and other lab strains contain a G970R mutation which eliminates Cd transport function; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily. | Boron efflux transporter of the plasma membrane; binds HCO3-, I-, Br-, NO3- and Cl-; has similarity to the characterized boron efflux transporter A. thaliana BOR1. | 0.472 |
| PCA1 | YGL114W | YBR295W | YGL114W | Cadmium transporting P-type ATPase; may also have a role in copper and iron homeostasis; stabilized by Cd binding, which prevents ubiquitination; S288C and other lab strains contain a G970R mutation which eliminates Cd transport function; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily. | Putative protein of unknown function; predicted member of the oligopeptide transporter (OPT) family of membrane transporters. | 0.475 |
| RAV1 | YGL114W | YJR033C | YGL114W | Regulator of V-ATPase in vacuolar membrane protein 1; Subunit of RAVE complex (Rav1p, Rav2p, Skp1p); the RAVE complex promotes assembly of the V-ATPase holoenzyme; required for transport between the early and late endosome/PVC and for localization of TGN membrane proteins; potential Cdc28p substrate. | Putative protein of unknown function; predicted member of the oligopeptide transporter (OPT) family of membrane transporters. | 0.842 |
| RSN1 | YGL114W | YMR266W | YGL114W | Uncharacterized protein RSN1; Membrane protein of unknown function; overexpression suppresses NaCl sensitivity of sro7 mutant cells by restoring sodium pump (Ena1p) localization to the plasma membrane; Belongs to the CSC1 (TC 1.A.17) family. | Putative protein of unknown function; predicted member of the oligopeptide transporter (OPT) family of membrane transporters. | 0.494 |
| YDL086W | YGL114W | YDL086W | YGL114W | Putative carboxymethylenebutenolidase; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YDL086W is not an essential gene; Belongs to the dienelactone hydrolase family. | Putative protein of unknown function; predicted member of the oligopeptide transporter (OPT) family of membrane transporters. | 0.480 |
| YGL114W | AQY1 | YGL114W | YPR192W | Putative protein of unknown function; predicted member of the oligopeptide transporter (OPT) family of membrane transporters. | Aquaporin-1; Spore-specific water channel; mediates the transport of water across cell membranes, developmentally controlled; may play a role in spore maturation, probably by allowing water outflow, may be involved in freeze tolerance. | 0.527 |
| YGL114W | AQY2 | YGL114W | YLL052C | Putative protein of unknown function; predicted member of the oligopeptide transporter (OPT) family of membrane transporters. | Aquaporin-like protein 2; Water channel that mediates water transport across cell membranes; only expressed in proliferating cells; controlled by osmotic signals; may be involved in freeze tolerance; disrupted by a stop codon in many S. cerevisiae strains; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.529 |